Acquisition of Fluoride in Vivo by Enamel from Repeated Topical Sodium Fluoride Applications in a Fluoridated Area: A Preliminary Report

Mellberg, J.R.; Nicholson, C.R.; Miller, Barry G.; Englander, Harold R.

doi:10.1177/00220345680470051201

Cited by 17 publications

(3 citation statements)

References 4 publications

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“…To increase the amount of permanently bonded F ' in enamel, multiple treatments [Mellberg et al, 1970;D avies, 1973] as well as etching with acids [De P aolo, 1971;G edalia, 1971] have been studied in detail. The use of a single treatment, however, seems to be essential for use and ac ceptance in dental clinics and in the dental health programs.…”

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confidence: 99%

Fluoride Content in Human Enamel after Fluoride Application and Washing – An in vitro Study

Arends¹,

Schuthof²

1975

Caries Res

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The purpose of this study was to compare the F^–– acquisition of enamel of APF solutions, NH₄F containing solutions, organic fluoride solutions and a urethane lacquer-containing silane fluoride. The F^–– content as a function of the distance from the anatomical surface was studied after one application, after 24 h of washing in tap water and after 1 week of washing. The results indicate that one treatment with the F^–– containing lacquer introduces an amount of permanently deposited fluoride comparable to that of a great number of applications by the other solutions mentioned. The silane fluoride-containing lacquer introduces about 2,000 ppm of permanently bonded F^–– in an average surface of 8 μm thickness.

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confidence: 99%

Fluoride Content in Human Enamel after Fluoride Application and Washing – An in vitro Study

Arends¹,

Schuthof²

1975

Caries Res

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“…Deciduous teeth were collected from all children in the study and submitted to analysis for fluoride by previously described techniques [Mellberg et al, 1968;H eifetz et al, 1970], The procedure essentially consists of etching four thin layers with 0.5 n HC104 from blocks of sound enamel cut from buccal or lingual teeth surfaces (approximately 20 mm2) and analyzing the layers for fluoride and calcium. Etch times were 30, 30, 60 and 120 sec and resulted in layers approximately 10, 12, 20, and 40 «m thick, respectively.…”

Section: Methodsmentioning

confidence: 99%

Fluoride Uptake and Caries Inhibition from Self-Application of an Acidulated-Phosphate-Fluoride Prophylaxis Paste

Mellberg¹,

Peterson²,

Nicholson³

1974

Caries Res

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The anti-caries effect of semi-annual self-applications of an acidulated-phosphate-fluoride prophylaxis paste to the teeth of children living in non-fluoridated areas was studied. Analysis of exfoliated deciduous teeth revealed an increase in enamel fluoride concentration of 120 ppm at 5 μm in anterior teeth and 15–35 ppm in posterior teeth after each application. The acquired fluoride did not increase with further applications but instead was lost within six months. Clinical examinations revealed 21% fewer DFS in APF paste treated children than in placebo-treated children. The greatest caries inhibition was found on buccal-lingual surfaces where the difference was 35%.

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“…Enamel is not of homogeneous composition. Numerous studies have demonstrated the inverse relationship between fluoride content and depth from the surface (BRUDEVOLD, STEADMAN and SMITH, 1960;ISAAC et al, 1958;MELLBERG et al, 1968). Other enamel constituents also demonstrate variable concentrations that appear to be depth dependent (BATTISTONE, FELDMAN and REBA, 1967;SOREMARK and GRIN, 1966).…”

Section: Summary-techniquesmentioning

confidence: 99%

Infrared internal reflection spectroscopy of human enamel surfaces

Krutchkoff

Rowe

1971

Archives of Oral Biology

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Techniques previously utilized for chemical analysis of enamel surfaces are generally unsuitable for in-vivo testing. This study explored the utility of internal reflection spectroscopy (IRS) as a non-destructive method for enamel-surface analysis.Powders (enamel plus reference inorganic materials) and solids (flattened and unaltered enamel slabs) were analysed by IRS. Most samples were mounted in a Wilks Model 45 Micro-ATR Accessory and scanned from 2 to 25 pm to obtain i.r. spectra. Comparability of IRS data with that of transmission methods was established. Typical apatitic ~a phosphorous-oxygen absorption was observed at 1090 cm-' and 1040 cm-' in spectra of natural fluorapatites and enamel powders. Spectral differences were demonstrated between powdered and intact enamel. The presence of carbonate was conhrmed in both powdered and solid enamel. Intact surface enamel and fluorapatites failed to absorb at 630 cm-'. Weak absorption at 630 cm-r after disking of the enamel surface was interpreted as a relative loss of fluorapatite due to mechanical reduction to subsurface levels.Internal reflection spectroscopy enabled subtle chemical differences in enamel surface to be distinguished. This non-destructive method offers promise for in-vivu enamel surface analysis. SURFACE enamel represents the initial barrier to dental caries. Investigators have long realized that a thorough knowledge of the chemical nature of enamel is a prerequisite to the effective control of dental caries at its inception. While this rationale for enamel research is unquestioned, inability to detect subtle changes in the actual enamel surface is a shortcoming of available techniques. In addition, most methods require sample destruction to accomplish the analytical procedure. Thus available testing is limited not only by insensitivity to surface properties but also by unsuitability for in-viz90 analysis.At present, the dynamics of the incipient carious lesion are difficult to assess with precision. Magnification of tooth surfaces to several hundred times original dimensions is possible with light microscopy. Scanning electron microscopy affords even greater resolution (HOFFMAN, MCEWAN and DREW, 1968). However, the chemical nature of surface changes cannot be determined by these methods. In addition to the * Present address:

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Acquisition of Fluoride in Vivo by Enamel from Repeated Topical Sodium Fluoride Applications in a Fluoridated Area: A Preliminary Report

Cited by 17 publications

References 4 publications

Fluoride Content in Human Enamel after Fluoride Application and Washing – An in vitro Study

Fluoride Content in Human Enamel after Fluoride Application and Washing – An in vitro Study

Fluoride Uptake and Caries Inhibition from Self-Application of an Acidulated-Phosphate-Fluoride Prophylaxis Paste

Infrared internal reflection spectroscopy of human enamel surfaces

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