"l_neTritium Migration Analysis Program MOD1/CY04 (TMAP4) was written to be used .in analyzing experiments and for safety calculations that involve the injection, solution, t diffusion, trapping, release, and other related processes experienced by hydrogen isotopes in materials. Because of the desire to make it suitable for analyzing safety issues, it is important that TMAP4 be certified (verified and validated) at Quality Assurance LevelA. This report documents the work done to achieve that certification. The process includes assuring that the developed code meets the software requirements specified in the Software Quality Assurance Plan, verifying that the code functions in accordance with the written description and that it is self-consistent and internally correct, and validating
Fluoride acquisition by the deciduous and permanent teeth of schoolchildren who consumed fluoridated water was studied during repeated topical applications in plastic mouth applicators of gel drops containing acidulated phosphate sodium fluoride. The fluoride acquired by the outer enamel from the topical treatments appeared to be permanently bound and progressively increased with the number of treatments completed.
Fluoride acquisition by deciduous enamel of 11- to 14-year-old children, living in a fluoridated area, was studied during repeated topical applications of acidulated phosphate fluoride gel drops in plastic mouthpieces. Enamel fluoride progressively increased as the number of treatments increased, reaching a concentration of 1,785 ppm at a depth of 5μ after an average of 56 treatments.
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