“…In most studies with topical fluorides the teeth have been cleaned professionally with rub ber cup and pumice. This procedure has been based on the assumption that plaque and pellicle inhibit uptake of fluoride by en amel [Aasenden et al, 1968;Brudevold et al, 1957;Knutson et al, 1947], In several trials, however, considerable caries reduc tion has been reported without cleaning the teeth before application or rinses with topi cal fluorides [Englander et al, 1971;Ho rowitz et al, 1974;Koch, 1967;Torell and Ericsson, 1965]. The results of Bruun and Stoltze [1976], Tinanoff et al [1974Tinanoff et al [ , 1975 and Joyston-Bechal et al [1976] suggest that the uptake of fluoride by enamel from NaF, amine F or acidulated phosphate fluo ride solutions is not reduced by plaque and pellicle in vivo or in vitro.…”