Acral Angioosteoma Cutis

Song, Hyung Keun; Hong, Won Kyu; Han, Sung Hyub; Byun, Ji Won; Lee, Hyeon Sook; Choi, Gwang Seong; Shin, Jeong Hyun

doi:10.1097/dad.0b013e3181c11839

Cited by 6 publications

(7 citation statements)

References 11 publications

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“…Lamellar bone, cartilage, or lobular arrangements of capillaries are not features of acral angiosteoma. The exact pathogenesis of acral angioosteoma cutis is unclear2. We can postulate that the pathogenesis of acral angioosteoma cutis is similar to the process of ossification in other hemagiomas.…”

Section: Discussionmentioning

confidence: 95%

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Acral Angioosteoma Cutis

Lee

Shin

et al. 2011

Ann Dermatol

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Acral angioosteoma cutis is a rare disease first described in 2006 that is characterized by vascular proliferation with ossification at the acral area, and which bears clinical similarity to pyogenic granuloma. However, there is no lobular pattern in the capillary proliferation that is a typical histopathological feature in pyogenic granuloma. Metaplastic cutaneous ossification is associated with multiple skin diseases and inflammatory conditions such as scars, nevi, basal cell carcinomas, pilomatricomas, chondroid syringomas, and venous stasis. It is rarely associated with vascular proliferation diseases like hemangiomas and pyogenic granulomas. We report a case of capillary proliferation with ectopic bone formation in a 43-year-old female who presented with an ulcerative, dome-shaped subungual nodule on the left fourth toe, which appeared to be a pyogenic granuloma. Because the biopsy findings showed no lobular capillary proliferation, we determined that this case was consistent with acral angioosteoma cutis.

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Section: Discussionmentioning

confidence: 95%

“…The authors named these novel ossifying vascular lesions "acral angioosteomas." There is one other case report about this condition2. Because acral angioosteoma cutis is rare and looks very similar to pyogenic granuloma, it is important for clinicians to have knowledge about this condition.…”

Section: Introductionmentioning

confidence: 99%

Acral Angioosteoma Cutis

Lee

Shin

et al. 2011

Ann Dermatol

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“…The other theory is that undifferentiated mesenchymal cells undergo metaplastic differentiation in the setting of inflammation or hypoxia. In previous case reports, the investigators believed that the vascular proliferation in both AAOC and PG were induced by vascular endothelial growth factor (VEGF) 2, 3, 4. Endothelial cells produce signals such as bone morphogenic protein (BMP) to induce metaplastic differentiation and ectopic bone formation 9 .…”

Section: Discussionmentioning

confidence: 99%

“…Since then, there have been only 3 additional cases reported 2, 3, 4. This friable erythematous exophytic papule has clinical resemblance to pyogenic granuloma (PG) but has distinct histologic features.…”

Section: Introductionmentioning

confidence: 99%

Recurrent acral angioosteoma cutis in a pregnant patient

et al. 2016

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“…Since the introduction of the term in 2006 for a series of 11 cases, at least 3 additional cases have been reported under this name. [36][37][38] These lesions occur on any acral site and are often periungual. They clinically and microscopically resemble pyogenic granuloma, with many having ulceration and epidermal collarettes.…”

Section: Acral Angioosteoma Cutismentioning

confidence: 99%

Acral manifestations of soft tissue tumors

Paral

Petronic‐Rosic

2017

Clinics in Dermatology

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This group of biologically diverse entities is united by topographic localization to the hands and feet. Categorizing tumors by body site narrows the differential into a short list of possibilities that can facilitate accurate and rapid diagnosis. The goal of this review is to provide a practical approach to soft tissue tumors of acral locations for clinicians, pathologists, and researchers alike. What ensues in the following text is that tight coupling of the clinical picture and histopathologic findings should produce the correct diagnosis, or at least an abbreviated differential. The salient clinicopathologic, immunohistochemical, and molecular features are presented alongside current treatment recommendations for each entity.

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Acral Angioosteoma Cutis

Cited by 6 publications

References 11 publications

Acral Angioosteoma Cutis

Acral Angioosteoma Cutis

Recurrent acral angioosteoma cutis in a pregnant patient

Acral manifestations of soft tissue tumors

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