Acral chilblain‐like lesions following inactivated SARS‐CoV‐2 vaccination

Temiz, Selami Aykut; Abdelmaksoud, Ayman; Dursun, Recep; Vestita, Michelangelo

doi:10.1111/ijd.15619

Cited by 19 publications

(22 citation statements)

References 5 publications

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“…histopathological study. 9 Some of the cases previously reported [6][7][8][9] describe acral lesions on hands, like in our three patients. This is the first case-series of acral lesions, similar to chilblainlike lesions, related to SARS-CoV-2 mRNA vaccines with clinical images and histopathological study.…”

supporting

confidence: 68%

New‐onset acral lesions on hands after administration of mRNA‐1273 vaccine against SARS‐CoV‐2: clinical images and histopathological study of three cases

Revilla-Nebreda

Roncero-Riesco

Santos‐Briz

et al. 2021

Acad Dermatol Venereol

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supporting

confidence: 68%

New‐onset acral lesions on hands after administration of mRNA‐1273 vaccine against SARS‐CoV‐2: clinical images and histopathological study of three cases

Revilla-Nebreda

Roncero-Riesco

Santos‐Briz

et al. 2021

Acad Dermatol Venereol

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“…Sars-CoV-2 vaccine-related chilblain-like lesions are painful and have itching violaceous nodules in acral sites (toes and hands) resembling pernio and COVID toe. Chilblainlike lesions can develop in 4-12 days after the first dose of mRNA or inactivated SARS-CoV-2 vaccines (CoronaVac by Sinovac Life Sciences) [6,19,23,[39][40][41]. Topical glucocorticosteroids and antihistamines have been used with success [23].…”

Section: Vascular Lesionsmentioning

confidence: 99%

Cutaneous Adverse Reactions Associated with SARS-CoV-2 Vaccines

Bellinato

Maurelli

Gisondi

et al. 2021

JCM

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Many patients are receiving SARS-CoV-2 vaccinations, which have been associated with a variety of adverse effects. Cutaneous adverse reactions to SARS-CoV-2 vaccinations have been progressively reported, but they have not been reviewed according to their morphological clinical patterns. The objective of this review was to summarize the existing data concerning the cutaneous adverse reactions following SARS-CoV-2 vaccines and group them according to common morphological and pathogenetic patterns. We reviewed the English language literature up to 15 August 2021, using predefined keywords to identify the relevant studies evaluating cutaneous adverse reactions associated with SARS-CoV-2 vaccines. We search for recurrent morphological patterns sharing clinical signs and symptoms and physio-pathological mechanisms. Timing to onset following the first or booster dose of the vaccine, predisposing conditions, therapeutic management, and outcome were also collected. Among the dermatological manifestations associated with SARS-CoV-2 vaccinations, we distinguished: (1) new onset reactions and (2) flares of preexisting dermatoses. The most common were injection site reactions, affecting 30–70% and generally mild or moderate. Small case series or single case reports included filler reactions, exanthemas, vascular lesions, urticaria, eczematous dermatitis, autoimmune bullous reactions, and severe cutaneous adverse reactions. In addition, the exacerbation of chronic immuno-mediated dermatoses (mainly psoriasis and atopic dermatitis) and reactivations of herpes infection were reported. The cutaneous reactions were generally mild, self-limiting, and resembled common cutaneous drug eruptions and/or COVID-19 skin manifestations.

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“…According to the FDA, the Moderna COVID-19 vaccine is capable of causing reactions like facial and lip swelling in patients with a history of dermal fillers [ 77 ]. Two cases of recipients developing acral chilblain-like lesions seven days postvaccination with CoronaVac have been reported [ 78 ].…”

Section: System-based Aefimentioning

confidence: 99%

Adverse Events following Immunization with COVID-19 Vaccines: A Narrative Review

Bhandari

Rayamajhi

Lamichhane

et al. 2022

BioMed Research International

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Numerous COVID-19 vaccines are being administered to people around the world. Adverse events following immunization (AEFI) with COVID-19 vaccines have been reported by health care workers as well as surveillance bodies. A wealth of information on the efficacy and safety of vaccines exists in the literature, and the knowledge in this sector is growing exponentially. A narrative literature review was conducted on sources accessed from PubMed, Google Scholar, and Cochrane Review from March 2021 to July 2021. This review is aimed at describing AEFI associated with currently available COVID-19 vaccines, with an emphasis on narrating probable AEFI, and at assisting in a better understanding of the COVID-19 vaccines.

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Acral chilblain‐like lesions following inactivated SARS‐CoV‐2 vaccination

Cited by 19 publications

References 5 publications

New‐onset acral lesions on hands after administration of mRNA‐1273 vaccine against SARS‐CoV‐2: clinical images and histopathological study of three cases

New‐onset acral lesions on hands after administration of mRNA‐1273 vaccine against SARS‐CoV‐2: clinical images and histopathological study of three cases

Cutaneous Adverse Reactions Associated with SARS-CoV-2 Vaccines

Adverse Events following Immunization with COVID-19 Vaccines: A Narrative Review

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