Action du facteur P sur les artères de l’embryon de poulet cultivées <i>in vitro</i>

Pharmacologic Effects of Flavonoids on Blood Vessels

“…Of these, mention must first be made of the interesting studies by Capelli et al [1968], Chorioallantoic and mesenteric arteries of 9-to 19-day-old chicken embryos were cultivated on a standard Wolff and Haffen medium, where the arteries exhibited definite signs of cell damage. The addition of P factor to the culture resulted in the survival of the arteries: No sign of injury could be seen, and the musculature remained.…”

“…That this should be given in Fribourg is not mere chance, for it was here that our hosts made their important findings, such as the fact that the P factor is essential for the development and maintenance of the normal structures of vessels cultivated in vitro [Capelli et al, 1968], This account is divided into five parts, dealing in turn with the effects of flavonoids on the size of the blood vessels; studies on isolated blood vessels; the effect on capillary permeability; the effect on capillary resistance; and the mechanism of action of flavonoids.…”

Effect of O-(β-Hydroxyethyl)-Rutosides on Oedema in Chronic Venous Insufficiency of the Lower Limb

“…Its mode of action has not been completely elucidated but has been shown to affect the energy metabolism of the cell [8,9] and to have a protective effect on connective tissue [2,3,4],…”