Activated carbon-plasticised agarose composite films for the adsorption of thiol as a model of wound malodour

Illsley, Matthew; Akhmetova, Alma; Bowyer, Cressida; Nurgozhin, Talgat; Mikhalovsky, Sergey V.; Farrer, Joan; Dubruel, Peter; Allan, Iain

doi:10.1007/s10856-017-5964-x

Cited by 11 publications

(10 citation statements)

References 25 publications

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“…With the final aim to develop odor‐adsorbing hydrogels, 0.5% w/w powdered AC [ 11 ] was added to the polymer solutions prior to UV cross‐linking. Higher AC contents inhibited the radical polymerization of the hydrogel precursors.…”

Section: Resultsmentioning

confidence: 99%

“…This makes it difficult to continuously use them on patients who suffer from malodorous wounds. [ 11 ]…”

Section: Introductionmentioning

confidence: 99%

“…This makes it difficult to continuously use them on patients who suffer from malodorous wounds. [11] As malodorous wounds often display high levels of exudate, hydrogels are of particular interest to treat these wounds. Hydrogels, defined as 3D hydrophilic polymeric materials that can absorb large amounts of water without dissolving, possess a lot of the desirable properties of an ideal wound dressing.…”

Section: Introductionmentioning

confidence: 99%

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Activated Carbon Containing PEG‐Based Hydrogels as Novel Candidate Dressings for the Treatment of Malodorous Wounds

Minsart

Mignon

Arslan

et al. 2020

Macro Materials & Eng

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Malodorous wounds have a detrimental effect on the patient's well‐being. A dressing combining the properties of hydrogels and activated carbon (AC) would be beneficial for the treatment of these wounds, controlling wound exudate while adsorbing malodor‐causing compounds. The present work involves the use of acrylate‐endcapped, urethane‐based precursors (AUPs) and methacrylated alginate (AlgMOD). AUPs are synthesized with a varying poly(ethylene glycol) backbone molar mass (2–20 kg mol−1) to tune mechanical and swelling properties, whereas methacrylated alginate, known for its hemostatic properties, enables chemical cross‐linking. Blends of AUP and AlgMOD with AC are processed into hydrogel sheets and electrospun membranes. The results indicate tunable mechanical (Young's moduli 0.03–0.63 MPa) and swelling properties (2.2–34.9 gwater ) along with high gel fractions (>85%). The sheets are compared with commercial odor‐adsorbing dressings (Carbonet and Carboflex), enabling benchmarking. AUP sheets (8 and 10 kg mol−1) containing 0.5% w/w AC show strong adsorption (>90% after 24 h) of crystal violet. The obtained (core–shell AlgMOD/AUP) fibers are visualized using scanning and transmission electron microscopy. Indirect cell tests reveal the developed materials to be biocompatible. In conclusion, a hydrogel‐based odor‐adsorbing wound dressing is successfully synthesized and holds promise for malodorous wound healing.

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Section: Resultsmentioning

confidence: 99%

“…This makes it difficult to continuously use them on patients who suffer from malodorous wounds. [ 11 ]…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Activated Carbon Containing PEG‐Based Hydrogels as Novel Candidate Dressings for the Treatment of Malodorous Wounds

Minsart

Mignon

Arslan

et al. 2020

Macro Materials & Eng

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“…Figure 3 displays the chemical structures of PBE, DGEBA epoxy, and PU. On the other hand, biopolymer composites are ordinarily prepared via solution processing [37]. Figure 4 demonstrates the chemical structures of cellulose, chitin, chitosan, and agarose.…”

Section: Polymer Composite Materialsmentioning

confidence: 99%

Application of Quaternary Ammonium Compounds as Compatibilizers for Polymer Blends and Polymer Composites—A Concise Review

Shamsuri

Jamil

2021

Applied Sciences

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A wide variety of quaternary ammonium compounds (QACs) have escalated the attraction of researchers to explore the application of QACs. The compounds have frequently been synthesized through alkylation or quaternization of tertiary amines with alkyl halides. Recently, QACs have been applied to compatibilize polymer blends and polymer composites in improving their thermo-mechanical properties. This concise review concentrates on the application of two types of QACs as compatibilizers for polymer blends and polymer composites. The types of QACs that were effectively applied in the blends and composites are quaternary ammonium surfactants (QASs) and quaternary ammonium ionic liquids (QAILs). They have been chosen for the discussion because of their unique chemical structure which can interact with the polymer blend and composite components. The influence of QASs and QAILs on the thermo-mechanical properties of the polymer blends and polymer composites is also described. This review could be helpful for the polymer blend and polymer composite researchers and induce more novel ideas in this research area.

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“…PAC is also known for its odor-absorbing properties. It is used for the adsorption of wound malodor in absorbent dressing [18,19].…”

Section: Introductionmentioning

confidence: 99%

Physical Properties of Starch/Powdered Activated Carbon Composite Films

et al. 2021

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In the present study, starch/powdered activated carbon composite films were prepared by incorporating various amounts of powdered activated carbon (PAC)—1–5, 10, and 15 %—into a starch matrix, using the solvent casting method. The effect of PAC addition on the biopolymer film was investigated. The mechanical properties were examined by ultra-nanoindentation, nanoscratch, and micro-tensile tests. Since the mechanical properties of biopolymer films are correlated with their structure, the effect of PAC addition was tested using X-ray diffraction. The surface parameters morphology and wettability were analyzed by atomic force microscopy (AFM) and contact angle measurements. The barrier properties were examined by determining water vapor permeability and the water solubility index. The obtained results did not show a monotonic dependence of the mechanical parameters on PAC content, with the exception of the maximum strain, which decreased as the amount of the additive increased. The visible effect of PAC addition was manifested in changes in the adhesive force value and in water vapor permeability (WVP). The barrier properties decreased with the increase of the filler content.

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Activated carbon-plasticised agarose composite films for the adsorption of thiol as a model of wound malodour

Cited by 11 publications

References 25 publications

Activated Carbon Containing PEG‐Based Hydrogels as Novel Candidate Dressings for the Treatment of Malodorous Wounds

Activated Carbon Containing PEG‐Based Hydrogels as Novel Candidate Dressings for the Treatment of Malodorous Wounds

Application of Quaternary Ammonium Compounds as Compatibilizers for Polymer Blends and Polymer Composites—A Concise Review

Physical Properties of Starch/Powdered Activated Carbon Composite Films

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