Activity of &lt;i&gt;Bryophyllum pinnatum&lt;/i&gt; S. Kurz extracts on respiratory tract pathogenic bacteria

Mudi, SY; Ibrahim, H.

doi:10.4314/bajopas.v1i1.57512

Cited by 13 publications

(12 citation statements)

References 12 publications

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“…The ability of extracts from FOPF inhibits bacterial growth in the moderate to strong, because the diameter of the inhibition zone ranges from 6.67-12.83 mm. In accordance with the statement of Davis and Stout [29] and Mudi and Ibrahim [30] if the diameter of the inhibition zone is more than 6 mm, the extract has antimicrobial activity with a moderate to strong category. Table 5 shows the diameter of the inhibitory zone in Gram-negative bacteria (E. coli) generally greater than the Gram-positive bacteria (S. aureus).…”

Section: Antimicrobial Activity Test Of Extracts From Fopf (In Vitro)supporting

confidence: 77%

Nutritional Content and Characteristics of Antimicrobial Compounds from Fermented Oil Palm Fronds (Elaeis guineensis Jacq.)

Febriana¹,

Zam

Febriyanti³

et al. 2020

J.Trop.Life.Science

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This research was conducted to determine physical quality, the nutritional quality and characteristics of antimicrobial compounds from fermented oil palm fronds (FOPF). This research was carried out using a Complete Randomized Design with 4 treatments and 4 replications. The following treatments were performed by the addition of different additives namely: 10% poultry manure, 10% cow feces, 5% urea and 5% molasses. All treatments were extracted in stages using n-hexane, ethyl acetate and methanol. The observed parameters were physical quality (pH, aroma, color, and texture), nutritional quality (neutral detergent fiber (NDF), acid detergent fiber (ADF), hemicellulose, cellulose and lignin), yield of extract, class of bioactive compounds and the antimicrobial activity test of extracted compounds. The data were analyzed using a one-way analysis of variance and differences between treatments were tested using Duncan's multiple range test. The addition of different additives has a very significant effect (P < 0.01) on the lignin content; significant effect (P < 0.05) on pH, aroma, color and texture; and no effect on the content of NDF, ADF, hemicellulose and cellulose. The highest yield of extract was obtained from methanol extract with the addition of poultry manure. The methanol extract on the addition of poultry manure and urea were identified as compounds in the steroid, tannin and phenolic classes. The highest antimicrobial activity test against Escherichia coli (12.83 mm) was obtained from FOPF extract (1%) with addition of poultry manure, while highest antimicrobial activity test against Staphylococcus aureus (11.67 mm) was obtained from FOPF extract (4%) with addition of molasses. The conclusion of this research was FOPF with addition of poultry manure provides good physical quality, nutritional quality and can inhibit the growth of E. coli and S. aureus at a concentration of 1%.

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Section: Antimicrobial Activity Test Of Extracts From Fopf (In Vitro)supporting

confidence: 77%

Nutritional Content and Characteristics of Antimicrobial Compounds from Fermented Oil Palm Fronds (Elaeis guineensis Jacq.)

Febriana¹,

Zam

Febriyanti³

et al. 2020

J.Trop.Life.Science

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“…Tannins are also reported to have various physiological effects like anti-irritant, antisecretolytic, antiphlogistic, antimicrobial and antiparasitic effects. Phytotherapeutically, tannin containing plants are used to treat non-specific diarrhoea, inflammations of mouth and throat and slightly injured skins [7]. This study revealed moderate in vitro antibacterial activity against test bacterial isolates at higher concentrations while at lower concentrations ranging from 25.0 to 6.25mg/ml, no inhibition zone was observed.…”

Section: Discussionmentioning

confidence: 72%

“…The plant has been found to possess antibacterial activity against several bacterial pathogens including Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Different solvents such as aqueous, ethanol, methanol and n-hexane have been used for extraction and the respective extracts have shown varying degree of antibacterial actions against selected pathogens [7]. Irrespective of the researches so far, adequate information on the antibacterial activity of the plant extract is very important.…”

Section: Introductionmentioning

confidence: 99%

In vitro Antibacterial Efficacy of Bryophyllum pinnatum Leaf Extracts

Okpoho

Chukwuka

Evbuomwan

2019

SAJRM

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A study on the antibacterial activities of Bryophylum pinnatum against multidrug resistant bacterial pathogens was carried out in this research. Air-dried and powered Bryophylum pinnatum leaves was extracted using ethanol and aqueous solvents. Five bacteria strains including Staphylococcus aureus, Streptococcus pneumoniae, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa were obtained from the University of Benin Teaching Hospital and they were preliminarily identified using standard microbiological methods. Antibacterial activity was carried out using agar well diffusion method. Mean zone diameter of inhibition in aqueous extract ranged from 9.20±0.17-10.50±0.50mm and 9.30±0.33- 10.33±0.89mm against Escherichia coli and Staphylococcus aureus respectively at 25-100mg/ml. In the ethanol extract, mean zone of inhibition ranged from 9.50±0.28-13.33±0.88mm and 10.67±0.67-19.00±0.58mm at concentration range of 6.25-100mg/ml. Minimum inhibitory concentrations of ethanol extract ranged from 6.25-100 mg/ml against bacterial strains. While those of aqueous extract ranged from 25-100 mg/ml against bacterial isolates. Minimum bactericidal/fungicidal concentrations of ethanol extract ranged from 25-50 mg/ml. While in the aqueous extract, value was 50 mg/ml and against bacteria. The test bacterial pathogens were found to possess multiple drug resistance potential with multidrug resistance index ranging from 0.3 – 0.5. This study has shown that multidrug resistant clinical bacterial pathogens are sensitive to aqueous extract of Bryophyllum pinatum.

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“…The GP extract tested in our study showed a three-fold lower MIC (2.5 mg/mL) on S. aureus than the BP methanol extract (6.25 mg/mL), suggesting that methanol is a better solvent for extraction of constituents with antibacterial activity than water. In addition, the GP extract exerted a four-to six-fold stronger inhibitory potential on S. aureus than the BP ethanol extract (MIC ¼ 10 mg/mL) obtained from B. pinnatum Kurz [38]. Considering the estimated maximal dose without adverse effects (1 mg/kg bw) in rats for aqueous GP extracts [19], our result (MIC ¼ 2.5 mg/mL) suggests that systematic application of the GP extract for treatment of Grampositive bacterial infections could be problematic.…”

Section: Antibacterial Activity Of Total Gp Extractmentioning

confidence: 92%

Anti-Herpes Simplex virus and antibacterial activities of Graptopetalum paraguayense E. Walther leaf extract: a pilot study

Zaharieva

Genova-Kalоu

Dincheva

et al. 2019

Biotechnology & Biotechnological Equipment

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Graptopetalum paraguayense E. Walther (GP) belongs to the Crassulaceae family and has several health benefits. In the present study we evaluated the cytotoxic, anti-Herpes Simplex virus (HSV) and antibacterial activities of a total methanol/water GP extract. The results from the cytotoxicity investigation of the tested extract showed a high cell tolerable concentration range. The GP extract demonstrated a significant inhibitory effect on the wild-type HSV-1 strain Victoria in a concentration of 0.0001 mg/mL equal to the maximal nontoxic concentration (with 97.5% protection of the cells). Regarding the acyclovir-resistant mutant HSV-2 strain PU and wild-type HSV-2 strain Bja, the antiviral activity and selectivity of the extract were very low, with EC 50 values from 0.1 to 0.01 mg/mL, and the selectivity index ranging from 25 to 250, respectively. The GP extract exhibited selective inhibitory activity also on the growth of Gram-positive bacterial pathogens, with Staphylococcus aureus being most sensitive. It also prevented the formation of MRSA biofilm up to 50% at a concentration of 1.6 mg/mL and up to 90% at a concentration of 2.5 mg/mL. The anti-herpetic and antibacterial activities demonstrated in our investigation are probably related to the presence of phenols, and in particular gallic acid. The antimicrobial activity of the GP extract holds a promise for the future development of nutrition supplements based on G. paraguayense and therefore warrants further studies aimed at isolating biologically active compounds or mixtures thereof with subsequent in-depth investigation of their anti-HSV and antibacterial mechanisms of action.

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Activity of <i>Bryophyllum pinnatum</i> S. Kurz extracts on respiratory tract pathogenic bacteria

Cited by 13 publications

References 12 publications

Nutritional Content and Characteristics of Antimicrobial Compounds from Fermented Oil Palm Fronds (Elaeis guineensis Jacq.)

Nutritional Content and Characteristics of Antimicrobial Compounds from Fermented Oil Palm Fronds (Elaeis guineensis Jacq.)

In vitro Antibacterial Efficacy of Bryophyllum pinnatum Leaf Extracts

Anti-Herpes Simplex virus and antibacterial activities of Graptopetalum paraguayense E. Walther leaf extract: a pilot study

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