Acupuncture Improves Peri-menopausal Insomnia: A Randomized Controlled Trial

Fu, Cong; Zhao, Na; Liu, Zhen; Yuan, Lu-Hua; Xie, Chen; Yang, Wen‐Jia; Yu, Xintong; Yu, Hui; Chen, Yunfei

doi:10.1093/sleep/zsx153

Cited by 68 publications

(81 citation statements)

References 38 publications

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“…Fu et al [38] 76 peri-menopausal women with insomnia Acupuncture PSQI Acupuncture can contribute to a clinically relevant improvement in the short-term treatment of PMI, both subjectively and objectively.…”

Section: Sleep Disorders Vasomotor Symptoms Menopausal Hormone Thermentioning

confidence: 99%

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Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

et al. 2019

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Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the literature. The latter yielded results on VMS, insomnia, circadian rhythm disorders, obstructive sleep apnea (OSA) and restless leg syndrome (RLS). Overall, the studies show that menopausal hormone therapy (MHT) improves VMS, insomnia, and mood. Several antidepressants can improve insomnia, either on their own or in association with MHT; these include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and mirtazapine. Long-term benefits for postmenopausal insomnia may also be achieved with non-drug strategies such as cognitive behavioral therapy (CBT) and aerobic exercise. Continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) both reduce blood pressure and cortisol levels in postmenopausal women suffering from OSA. However, the data regarding MHT on postmenopausal restless legs syndrome are conflicting.

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Section: Sleep Disorders Vasomotor Symptoms Menopausal Hormone Thermentioning

confidence: 99%

“…Other non-pharmacological options such as acupuncture [38], mindfulness, reflexology, exercise, and yoga have shown some positive results in small groups, but these have yet to be confirmed in larger studies. A short-term randomized trial has found a positive effect of acupuncture on perimenopausal insomnia [38].…”

Section: Insomniamentioning

confidence: 99%

Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

et al. 2019

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“…Insomnia is characterized by having difficulty falling asleep, frequent nocturnal wakings with difficulty falling back asleep [4] and unexplained pain. A study conducted by the National Institutes of Health estimates the prevalence of insomnia in menopausal women at 40-50% [5][6][7][8]. Women who experience poor sleep quality during the MT are more likely to have critical problems [9] such as depression, anxiety, memory and cognitive deprivation, cardiovascular disease and reduced quality of life [3,4].…”

Section: Background Backgroundmentioning

confidence: 99%

“…Acupuncture, an important part of Traditional Chinese Medicine (TCM), has been used for thousands of years in China to treat various diseases including sleep disorders [5]. Many studies have confirmed the efficacy of acupuncture for primary insomnia and related depressive disorders [16][17][18].…”

Section: Background Backgroundmentioning

confidence: 99%

Effect of acupuncture on insomnia in menopausal women: A Study protocol for a Randomized Controlled Trial

Yin

et al. 2018

Preprint

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Background: China today has high occurrences of insomnia in perimenopausal women. Some studies have shown that acupuncture might be effective in treating primary insomnia and insomnia related to depression and stroke. Although there are some programs supporting insomnia during the menopausal transition, there are few randomized controlled trials to provide evidence regarding their effectiveness. We design a randomized controlled trial of suitable sample size to verify the effectiveness of acupuncture in patients with insomnia during the menopausal transition and to form an optimized acupuncture treatment protocol. Method/Design: In this randomized, single-site, single-blind, placebo-controlled trial, 84 eligible patients will be recruited and randomly assigned to either the acupuncture group (n = 42) or the sham control group (n = 42) in a 1:1 ratio. Participants will receive a total of 18 sessions of treatment for eight consecutive weeks. Treatments will be given three times per week in the first four weeks, twice a week for the next two weeks and finally treatment once weekly for the final two weeks. Treatment will utilize eight main acupoints (GV20, GV24, GV29, RN6, RN4, SP6, HT7, EX-HN22), and extra two acupoints based on syndrome differentiation. The primary outcome will be assessed using the Pittsburgh Sleep Quality Index (PSQI). The secondary outcomes will be measured by sleep parameters recorded in the Actigraphy (SE, TST, SA), Insomnia Severity Index (ISI), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and Menopause Quality of Life (Men-QOL). The primary outcomes will be assessed at baseline, week four, week eight, and first and the third month following the end of treatment. Discussion: If the results confirm that acupuncture is effective and safe for the treatment on insomnia in menopausal women, this positive outcome could provide evidence for clinical application.

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“…In China, patients have multiple choices for treatment of insomnia, including acupuncture [4][5][6][7], traditional medicine (Chinese, Mongolian, Tibetan traditional medicine) [8,9] and concerns about western medicine [10], but psychotherapy is not very accessible, and even CBT-I isn't available in most hospitals. In Inner Mongolia, there is conventional Mongolian mind-body interactive psychotherapy (MMIP), doctors mainly use MMIP and traditional Mongolian medicine, and achieve better outcomes in multiple psychosomatic diseases than just using medication.…”

Section: Introductionmentioning

confidence: 99%

New Method for Insomnia Mongolian Mind–Body Interactive Psychotherapy in the Assessment of Chronic Insomnia: A Retrospective Study

Lan

Jiang

et al. 2018

Adv Ther

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Acupuncture Improves Peri-menopausal Insomnia: A Randomized Controlled Trial

Abstract: Acupuncture for peri-menopause insomnia: a randomized controlled trial, http://www.chictr.org.cn/showproj.aspx?proj=12118 ChiCTR-IPR-15007199, China.

Cited by 68 publications

References 38 publications

Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

Effect of acupuncture on insomnia in menopausal women: A Study protocol for a Randomized Controlled Trial

New Method for Insomnia Mongolian Mind–Body Interactive Psychotherapy in the Assessment of Chronic Insomnia: A Retrospective Study

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