Acute Abdomen in Henoch-Schönlein Purpura

Lawes, Daniel; Wood, Jaime

doi:10.1177/014107680209501009

Cited by 8 publications

(9 citation statements)

References 6 publications

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“…In our case report, steroid therapy was commenced a week before the patient developed abdominal symptoms. Similar findings have been described previously (5,6,9). It is impossible to be certain about the role of oral steroids in the small bowel perforation in this case, but it would appear unlikely that glucocorticoid therapy would be responsible for patchy small bowel ischaemia.…”

Section: Discussionsupporting

confidence: 92%

Small bowel ischaemia and perforation as a complication of Henoch-Schonlein Purpura in a previously healthy adult

Locke

Stewart

Patel

et al. 2012

Journal of Surgical Case Reports

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Section: Discussionsupporting

confidence: 92%

Small bowel ischaemia and perforation as a complication of Henoch-Schonlein Purpura in a previously healthy adult

Locke

Stewart

Patel

et al. 2012

Journal of Surgical Case Reports

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“…The most common complaint of GI involvement was abdominal pain, often associated with vomiting. 7,8 Joint involvement was noted in 31/124 (25%) of patients and characterized by warmth, tenderness and swelling of the joints, particularly the large joints (specifically the ankles and knees). Joint involvement left no permanent deformities.…”

Section: Patient Characteristicsmentioning

confidence: 99%

Kawasaki disease and Henoch–Schönlein purpura – 10 years’ experience of childhood vasculitis at a university hospital in Taiwan

Teng

Wang

et al. 2012

Journal of Microbiology, Immunology and Infection

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“…In these cases, the CT scan shows a layered appearance of wall enhancement and prominent mesenteric vessels supplying the abnormal bowel loops. Patients may rarely develop steatorrhea [85], appendicitis [86], enteroenteric fistulas [87], infarction [72,88], and intramural hemorrhage [89].…”

Section: Gi Features Of Hspmentioning

confidence: 99%

Gastrointestinal Manifestations of Henoch-Schonlein Purpura

2008

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Henoch-Schonlein Purpura (HSP) is the most common systemic vasculitis in childhood. The diagnostic criteria include palpable purpura with at least one other manifestation -- abdominal pain, IgA deposition, arthritis or arthralgia, or renal involvement. Immune complex deposits result in necrosis of the wall of small- and medium-sized arteries with infiltration of tissue by neutrophils and deposition of nuclear fragments, a process called leukocytoclastic vasculitis (LCV). It is often associated with infections, medications, or tumors. It may coexist with or mimic Crohn's disease. Periumbilical and epigastric pain worsens with meals, from bowel angina. Bleeding is usually occult or, less commonly, associated with melena. Intussusception, the most common surgical complication, is usually ileo-ileo or ileo-colic. Perforations, usually ileal, may occur spontaneously or be associated with intussusception. Ultrasound, recommended as the first diagnostic test, and CT scans may show intussusception and asymmetric bowel wall thickening mainly involving the jejunum and ileum. There are a range of endoscopic findings including gastritis, duodenitis, ulceration, and purpura, with the second portion of the duodenum characteristically being involved more than the bulb. Intestinal biopsies show IgA deposition and LCV in the submucosal vessels. Superficial biopsies may show inflammation, ulceration, edema, hemorrhage, and vascular congestion, presumably due to vasculitis-induced mucosal ischemia. The efficacy of corticosteroids in preventing severe complications or relapses is controversial. The majority of patients, however, improve spontaneously.

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Acute Abdomen in Henoch-Schönlein Purpura

Cited by 8 publications

References 6 publications

Small bowel ischaemia and perforation as a complication of Henoch-Schonlein Purpura in a previously healthy adult

Small bowel ischaemia and perforation as a complication of Henoch-Schonlein Purpura in a previously healthy adult

Kawasaki disease and Henoch–Schönlein purpura – 10 years’ experience of childhood vasculitis at a university hospital in Taiwan

Gastrointestinal Manifestations of Henoch-Schonlein Purpura

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