Acute annular outer retinopathy with systemic symptoms

Simunovic, Matthew P.; Hughes, Edward; Townend, Bradley S.; Ho, I-Van

doi:10.1038/eye.2009.252

Cited by 9 publications

(16 citation statements)

References 4 publications

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“…In the acute phase of the disease, the border of the affected and unaffected retina typically had a more discretely white appearance. The area of the involved retina varied from only a few disc diameters, 14 to almost half the retina extending from the optic nerve to the ora, as shown in Case 2. In 9 cases (45.0%), including the 2 in this report, beyond the leading edge of the affected retina were either small white satellite intraretinal spots 5,6,13,15 or larger rings.…”

Section: Clinical Characteristicsmentioning

confidence: 83%

“…In 18 cases (90.0%), including the 2 from our work, FA was reported. 1,2,[5][6][7][8][9][10][11][12]14,15 In 7 (38.9%) of these, the whitish-gray annular retinal change seen clinically appeared unremarkable on FA. 1,2,5,6,11,12 In 3 (16.7%) of these cases, the overall angiogram was normal early in the disease, 11,12,15 while in another 2 cases (11.1%), delayed dye transit in the involved quadrant was observed.…”

Section: Clinical Characteristicsmentioning

confidence: 98%

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Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

Gupta

Iaboni

Seamone

et al. 2019

Journal of VitreoRetinal Diseases

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Acute annular outer retinopathy (AAOR) is an uncommon disease. We present 2 illustrative cases and demonstrate disease evolution using multimodal imaging. The 18 previously reported cases in the peer-reviewed English literature are also reviewed. Methods: We conducted a case series and literature review. Results: We observed complete structural resolution by spectral-domain optical coherence tomography (SD-OCT) and ultra-widefield fundus autofluorescence in 1 case. In the literature review, 20 cases of AAOR were identified, including the 2 we have presented. Fifteen cases were unilateral and 5 bilateral, resulting in a total of 25 eyes with AAOR. Presenting symptoms included visual field defects (72%), decreased vision (48%), and photopsia (36%). Sixty-eight percent had a final visual acuity better than or equal to 20/40, while a minority (14%) were 20/200 or worse. Clinically, all eyes had a peripapillary annular band of gray-white opacification of the deep retina. Conclusions: We have reviewed and summarized the 18 previously reported cases of AAOR in the English literature and have shown for the first time that AAOR may undergo complete recovery of the external limiting membrane and ellipsoid zone on SD-OCT with resolution of disease. There is still much to be understood regarding the pathogenesis of and optimal management of AAOR.

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Section: Clinical Characteristicsmentioning

confidence: 83%

Section: Clinical Characteristicsmentioning

confidence: 98%

Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

Gupta

Iaboni

Seamone

et al. 2019

Journal of VitreoRetinal Diseases

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“…Visusabfall bei Beteiligung des hinteren Pols beschrieben [9]. Photopsien wurden bei der AAOR allerdings nur in 8 der 16 bisher in der englischsprachigen Literatur berichteten Fäl-le angegeben [3,5,[10][11][12][13][14]. Die Symptome treten initial meist unilateral auf, wobei die beschriebenen Netzhautverände-rungen bei ca.…”

Section: Diskussionunclassified

“…Der fluoreszenzangiographische Befund ist initial häufig regelrecht. Manchmal sind früh-zeitig im Krankheitsverlauf kleine peripapilläre Leckagen oder eine verlangsamte retinale Perfusion aufgrund der verengten Arterien im betroffenen Areal sichtbar [3,4,6,11,12]. Als Folge der RPE (retinales Pigmentepithel)-Atrophie ist der Farbstoff in der Choriokapillaris besser zu sehen, was als flächige Aufhellung erscheint [3][4][5]10].…”

Section: Diskussionunclassified

“…Diese Veränderungen können im mfERG nur einen Teil der Ableitungen betreffen [12] -wie in unserem Fall am rechten Auge. Im Gegensatz dazu deuten die verminderten Amplituden aller Ringe im mfERG sowie die reduzierten Zapfenantworten im Ganzfeld-ERG auf eine Mitbeteiligung des Netzhautzentrums des linken Auges hin, obwohl die Läsion nur im oberen Netzhautbereich funduskopisch sichtbar war.…”

Section: Introductionunclassified

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Progredientes Skotom mit Photopsiewahrnehmung

et al. 2015

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Acute annular outer retinopathy (AAOR) is a very rare variant of acute zonal occult outer retinopathy (AZOOR). Both variants are characterized by the perception of a progressive visual field defect and can be accompanied by photopsia. In contrast to AZOOR, a progressive whitish and annular demarcation of the involved retina is observed in AAOR using ophthalmoscopy. Optical coherence tomography (OCT) reveals morphological changes predominantly in the outer retinal layers. Although there is no proof of an effective therapy, in the case presented here further progression could be stopped by a combination of antiviral and immunosuppressive therapy.

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