Acute Biliary Pancreatitis

İlhan, Mehmet; Alış, Halil

doi:10.5772/26272

Cited by 2 publications

(3 citation statements)

References 26 publications

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“…It can be initiated by several factors, including gallstones, alcohol, trauma, infections and hereditary factors. About 75% of pancreatitis is caused by gallstones or alcohol 1 . The overall mortality rate of acute pancreatitis was 3.8%, mortality rate of severe acute pancreatitis was high as 16.3% and mortality rate of moderately severe acute pancreatitis as 4.08% 2 .…”

Section: Introductionmentioning

confidence: 99%

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Risk Factors Associated With Worsening of Acute Pancreatitis.

Dhar

Shafi

Singh

et al. 2021

ijmsdr

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Background: The aim of the present study was to investigate risk factors for developing more severe pancreatitis, including moderately severe (MSAP) and severe acute pancreatitis (SAP), in patients admitted with mild acute pancreatitis (MAP). Material/Methods: This was a hospital based retrospective and prospective study conducted in the Department of Gastroentrology, SKIMS Soura,Srinagar, Kashmir for a period of 2 years w.e.f. September 2017 to September 2019 on patients of all age groups with clinical/Laboratory/imaging findings suggestive of acute pancreatitis. The protocol of the study was approved by the Institutional Ethical Committee. Patients admitted with MAP to our hospital were included and prospectively evaluated. Possible risk factors for developing MSAP or SAP were Evaluated. Results: Risk factors like BMI >25kg/m2 was observed in 61 (19.3%) patients with mild pancreatitis and 142 (42.5%) patients with moderate to severe pancreatitis. Waist circumference >100cm was observed in 23 (7.3%) and 129 (38.6%) patients of mild and moderate to severe pancreatitis. High blood sugar >200mg/dl was observed in 37 (11.7%) patients with mild pancreatitis and 152 (45.2%) patients with moderate to severe pancreatitis. 27 (8.5%) and 167 (50%) patients of mild and moderate to severe pancreatitis had hematocrit >44 whereas 13 (4.1%) patients with mild pancreatitis and 140 (41.9%) patients with moderate to severe pancreatitis had CRP >150mg/dl. This table concluded that there is statistically significant association between high BMI >25 Kg/m2, waist circumference >100 cm, high blood sugar >200 mg /dl, hematocrit >44, CRP >150 mg/d and worsening of AP. Conclusions: Significant risk factors for developing MSAP or SAP in patients admitted with MAP included BMI (≥25 kg/m2), APACHE-II (≥5), and blood glucose level on admission (>11.1 mmol/L). These factors should be used in the prediction of more severe pancreatitis in patients admitted with MAP. Keywords: Obesity, Pancreatitis, Risk Factors

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Section: Introductionmentioning

confidence: 99%

“…The general belief today is that pancreatitis begins with the activation of digestive enzymes inside acinar cells, which cause acinar cell injury. The risk factors in acute pancreatitis can be classified as 1…”

Section: Introductionmentioning

confidence: 99%

Risk Factors Associated With Worsening of Acute Pancreatitis.

Dhar

Shafi

Singh

et al. 2021

ijmsdr

View full text Add to dashboard Cite

show abstract

“…About 80% of pancreatitis is caused by gallstones or alcohol. 2 The underlying reason of gallstone disease and other conditions causing acute pancreatitis is ductal hypertension resulting from ongoing exocrine secretion into an obstructed pancreatic duct. Elevated intraductal pressure, due to ongoing exocrine secretion, causes rupture of the smaller ductuli and leakage of pancreatic juice into the parenchyma.…”

mentioning

confidence: 99%

Early versus late laparoscopic cholecystectomy in acute biliary pancreatitis: a prospective randomised study

et al. 2022

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Background: In patients with acute biliary pancreatitis, cholecystectomy is mandatory to prevent further biliary events, but the precise timing of cholecystectomy for mild to moderate disease remain a subject of ongoing debate. The aim of this study is to assess the outcomes of early versus delayed cholecystectomy. We hypothesize that early cholecystectomy as compared to delayed cholecystectomy reduces recurrent biliary events without a higher peri-operative complication rate.Methods: Patients with mild to moderate ABP were prospectively randomized to either an early cholecystectomy versus a delayed cholecystectomy group. Recurrent biliary events, peri-operative complications, conversion rate, length of surgery and total hospital length of stay between the two groups were evaluated.Results: A total of 70 patients were enrolled at tertiary care hospital in central India. Of them, 35were randomized to the early group and 35 patients to the delayed group using simple randomization technique. Conclusions: In mild to moderate ABP, early laparoscopic cholecystectomy reduces the risk of recurrent biliary events without an increase in operative difficulty or perioperative morbidity.

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Acute Biliary Pancreatitis

Cited by 2 publications

References 26 publications

Risk Factors Associated With Worsening of Acute Pancreatitis.

Risk Factors Associated With Worsening of Acute Pancreatitis.

Early versus late laparoscopic cholecystectomy in acute biliary pancreatitis: a prospective randomised study

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