Acute effects of aroclor® 1254 (PCB) onIctalurus punctatus (Catfish)

Hejtmancik, E.; Armour, Chérie; Lewis, D. H.

doi:10.1007/bf01684962

Cited by 9 publications

(1 citation statement)

References 5 publications

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“…In the present study, turtles with higher concentrations of OCs exhibited a decreased ratio of albumin to globulin. This response was previously observed in fish exposed to Aroclor 1254 (Camp et al 1974). In addition, changes in these protein classes were correlated with PCB and DDE concentrations in Caspian tern and herring gull chicks from the Great Lakes (Grasman et al 2000a).…”

Section: Discussionsupporting

confidence: 81%

Associations between Organochlorine Contaminant Concentrations and Clinical Health Parameters in Loggerhead Sea Turtles from North Carolina, USA

Keller

Kucklick

Stamper

et al. 2004

Environ Health Perspect

159

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Widespread and persistent organochlorine (OC) contaminants, such as polychlorinated biphenyls (PCBs) and pesticides, are known to have broad-ranging toxicities in wildlife. In this study we investigated, for the first time, their possible health effects on loggerhead sea turtles (Caretta caretta). Nonlethal fat biopsies and blood samples were collected from live turtles for OC contaminant analysis, and concentrations were compared with clinical health assessment data, including hematology, plasma chemistry, and body condition. Concentrations of total PCBs (ΣPCBs), ΣDDTs, Σchlordanes, dieldrin, and mirex were determined in 44 fat biopsies and 48 blood samples. Blood concentrations of Σchlordanes were negatively correlated with red blood cell counts, hemoglobin, and hematocrit, indicative of anemia. Positive correlations were observed between most classes of OC contaminants and white blood cell counts and between mirex and ΣTCDD-like PCB concentrations and the heterophil:lymphocyte ratio, suggesting modulation of the immune system. All classes of OCs in the blood except dieldrin were correlated positively with aspartate aminotransferase (AST) activity, indicating possible hepatocellular damage. Mirex and ΣTCDD-like PCB blood concentrations were negatively correlated with alkaline phosphatase (ALP) activity. Significant correlations to levels of certain OC contaminant classes also suggested possible alteration of protein (↑ blood urea nitrogen, ↓ albumin:globulin ratio), carbohydrate (↓ glucose), and ion (↑ sodium, ↓ magnesium) regulation. These correlations suggest that OC contaminants may be affecting the health of loggerhead sea turtles even though sea turtles accumulate lower concentrations of OCs compared with other wildlife.

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Section: Discussionsupporting

confidence: 81%