Acute effects of cigarette smoking on multifocal electroretinogram

Abstract

Cigarette smoking may stimulate the central retinal areas in the acute phase. This effect may be related with the stimulant effect of nicotine on neurotransmission, deleterious effects on retinal and/or choroidal circulation, carbon monoxide toxicity and nicotine withdrawal.

The Effect of Chronic Smoking on the Pupil and Photostress Recovery Time

“…We were not able to do macular pigment density measurement in this study; however, normal FTVs in smokers suggest that chronic smoking in adults might not be associated with decreased macular pigment density. Increased FTV immediately after photostress, considering our findings from electrodiagnostic studies [11,12,13] suggests chronic, subclinical toxicity in the macula of chronic smokers. On the other hand, rapid adaptation to photostress may be beneficial in performing duties under glare, such as driving in the night.…”

“…We previously showed that acute smoking significantly hastens the latency time from eye to visual cortex [11], and this is associated with abnormalities in the macula detected by pattern electroretinography [12] and multifocal electroretinography [13]. Electrocortical activation shown in the previous studies and decrements in ocular blood flow in the acute phase indicated that this effect is mediated via nicotine’s action on neuronal systems [11,12,13,14].…”

“…Electrocortical activation shown in the previous studies and decrements in ocular blood flow in the acute phase indicated that this effect is mediated via nicotine’s action on neuronal systems [11,12,13,14]. Non-calpain-mediated oxidant pathway-related toxicity has been shown in rat neurosensory retinal (R28) cells [14].…”

A Knowledge-Attitude-Practise (Kap) Study to Assess the Awareness About The Adverse Effect of Tobacco Smoking on Eyes Among Medical Students in A Rural Based Medical College.

“…They also reported an increased risk of bilateral advanced AMD in current smokers and heavy smokers. They strongly recommended promotion of smoking cessation advice among general population with particular emphasis on current smokers with unilateral ARMD 5 . Apart from ARMD, cataract which is the other leading cause of severe visual impairment is also accelerated by smoking tobacco 6 .…”

Tobacco smoking influences on eye diseases and vision

“…It was shown in recent years that acute exposure to cigarette smoking may stimulate the central retinal areas measured by the increase of P1 amplitudes of multifocal electroretinography (mfERG)4 and have stimulant effects of pattern visual-evoked potentials (PERG) 5. It was speculated that this effect might be related to the stimulant effect of nicotine on neurotransmission, deleterious effects on retinal and/or choroidal circulation, carbon monoxide toxicity and nicotine withdrawal 4…”