Acute effects of intradialytic aerobic exercise on solute removal, blood gases and oxidative stress in patients with chronic kidney disease

Abstract

The acute intradialytic aerobic exercise increased phosphorus serum concentration and decreased total antioxidant capacity, reversing hypoxemia resulting from hemodialysis. The intradialytic exercise did not change the blood acid-base balance and the removal of solutes.

The effects of intradialytic exercise on hemodialysis adequacy: A systematic review

“…Five of seven studies showed a statistically significant result or a large effect size for increased potassium clearance and/or reduced serum concentrations with intradialytic exercise.…”

“…Seven of the acute studies utilized a within‐subject crossover design, with six of the seven randomizing the treatment order. One acute study implemented a randomized controlled design . Four of the intervention studies performed a randomized controlled trial, one study utilized a within subject crossover design, and two studies observed pre and post changes in an intervention group without a control comparison arm (1 group intervention) …”

“…Eight studies investigated the effects of an acute bout of exercise on dialysis adequacy, 3,[13][14][15][16][17][18][19] whilst seven studies performed a chronic intradialytic intervention. 20,21 Seven of the acute studies utilized a within-subject crossover design, 3,14,15 with six of the seven randomizing the treatment order.…”

Intradialytic exercise with blood flow restriction: Something to add to hemodialysis adequacy? Findings from a crossover study

“…[5][6][7][8][9][10][11][12]18 Intradialytic exercise increases solutes removal by increasing cardiac output, which, combined with higher metabolic need for the exercising muscle, leads to muscle vasodilation. [5][6][7][8][9][10][11][12]18 Intradialytic exercise increases solutes removal by increasing cardiac output, which, combined with higher metabolic need for the exercising muscle, leads to muscle vasodilation.…”

“…There has already been some evidence that intradialytic exercise increases the amounts of phosphorus eliminated in dialysate, [5][6][7][8][9] as well as Kt/V-urea, 10-12 a parameter of HD adequacy. There has already been some evidence that intradialytic exercise increases the amounts of phosphorus eliminated in dialysate, [5][6][7][8][9] as well as Kt/V-urea, 10-12 a parameter of HD adequacy.…”