Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing

Huang, Jing; Deng, Furong; Wu, Shaowei; Zhao, Yan; Shima, Masayuki; Guo, Bin; Liu, Qichen; Guo, Xinbiao

doi:10.1007/s12199-016-0531-5

Cited by 27 publications

(16 citation statements)

References 26 publications

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“…Although there is strong evidence of a short-term association between outdoor air pollution and reduced pulmonary function for general population studies in adults, our model estimates did not support effects of ambient BC or PM2.5 on pre-bronchodilator function, or of indoor or ambient exposures on post-bronchodilator function (Chen et al. 2017; Huang et al. 2016; Lepeule et al.…”

Section: Discussioncontrasting

confidence: 69%

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Effects of Indoor and Ambient Black Carbon and PM2.5 on Pulmonary Function among Individuals with COPD

Hart

Grady²,

Laden

et al. 2018

Environ Health Perspect

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Background: Particulate matter (PM) air pollution has been associated with decreased pulmonary function, but the exposure–response relationship in chronic obstructive pulmonary disease (COPD) patients is uncertain, and most studies have only focused on exposures to ambient pollution. Objectives: We aimed to assess associations between pulmonary function and indoor and ambient PM ( ) and black carbon (BC). Methods: Between November 2012 and December 2014, 125 patients with COPD (mean age, 73.4 y) who were not currently smoking and without known indoor BC sources were recruited. Indoor BC and were measured in each home for a week in each season, up to four times a year, followed by in-person spirometry pre- and post-bronchodilator. Ambient exposures were available from a central site monitor. Multivariable adjusted mixed effects regression models were used to assess associations scaled per interquartile range (IQR) of exposure. Results: There were 367 study visits; the median (IQR) indoor BC and were 0.19 (0.22) and 6.67 (5.80) , respectively. Increasing indoor exposures to BC were associated with decreases in pre-bronchodilator forced expiratory volume in 1 s and forced vital capacity (FVC), and . For example, in multivariable adjusted models, each IQR increase in indoor BC from the weekly integrated filter was associated with a [95% confidence interval (CI): , ] decrease in pre-bronchodilator . Increases in indoor were associated with decreases in and FVC of smaller magnitude than those for indoor BC; however, the results were less precise. Ambient BC was not associated with pre-bronchodilator pulmonary function, ambient was only associated with decreases in FVC and increases in , and neither indoor nor ambient BC or were associated with post-bronchodilator pulmonary function. Conclusions: Low-level exposures to indoor BC and , but not ambient exposures, were consistently associated with decreases in pre-bronchodilator pulmonary function. There was no association between exposures and post-bronchodilator pulmonary function. https://doi.org/10.1289/EHP3668

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Section: Discussioncontrasting

confidence: 69%

“…Exposures to PM2.5 have also been consistently associated with decreases in pulmonary function in general population epidemiologic studies (Chen et al. 2017; Huang et al. 2016; Lepeule et al.…”

Section: Introductionmentioning

confidence: 97%

Effects of Indoor and Ambient Black Carbon and PM2.5 on Pulmonary Function among Individuals with COPD

Hart

Grady²,

Laden

et al. 2018

Environ Health Perspect

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“…Similar evidence has been found in other cities such as Seoul and New York . While the health effects of underground air pollution have received considerably less attention, several studies suggest that subway PM has the same or even greater adverse health effect than ambient PM …”

Section: Introductionsupporting

confidence: 68%

“…6 While the health effects of underground air pollution have received considerably less attention, several studies suggest that subway PM has the same or even greater adverse health effect than ambient PM. [7][8][9] A review of the "Environmental Burden of Disease in Europe" ranked noise as the second greatest environmental risk factor to health, contributing to 8% of the burden of disease ascribable to environmental factors. 10 Moreover, several studies indicated that subway noise levels exceed the recommended community exposure level (55 dB) 11,12 and might result in health impairments.…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular benefits of reducing personal exposure to traffic-related noise and particulate air pollution: A randomized crossover study in the Beijing subway system

et al. 2018

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To assess the cardiovascular benefits of protecting against particulate air pollution and noise, we conducted a randomized crossover study with 40 young healthy college students from March to May 2017 in the underground subway, Beijing. Participants each received 4 treatments (no intervention phase [NIP], respirator intervention phase [RIP], headphone intervention phase [HIP], respirator plus headphone intervention phase [RHIP]) in a randomized order during 4 different study periods with 2-week washout intervals. We measured personal exposure to particulate matter (PM), noise and electrocardiogram (ECG) parameters (heart rate variability (HRV), heart rate (HR) and ST segment changes), ambulatory blood pressure (BP) continuously for 4 hours to investigate the cardiovascular effects. Compared with NIP, most of the HRV parameters increased, especially high frequency (HF) [21.1% (95% CI: 15.7%, 26.9%), 18.2% (95% CI: 12.8%, 23.9%), and 35.5% (95% CI: 29.3%, 42.0%) in RIP, HIP, and RHIP, respectively], whereas ST segment elevation and HR decreased for all 3 modes of interventions. However, no significant differences were observed in BP among the 4 treatments. In summary, short-term wearing of a respirator and/or headphone may be an effective way to minimize cardiovascular risk induced by air pollution in the subway by improving autonomic nervous function.

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“…Among the sources of pollution in cities, pollutants emitted by the car have been identified as a major cause of air pollution. The major components of such emissions include carbon monoxide (CO), carbon dioxide, volatile organic compounds, nitrogen oxides, particulate matter, and the others [ 6 – 9 ]. CO is the primary component of emissions from light-duty vehicles, and comprises approximately 77% of all pollutants emitted in terms of concentration [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Decreased blood pressure associated with in-vehicle exposure to carbon monoxide in Korean volunteers

Lee

Bae

Yang

et al. 2017

Environ Health Prev Med

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BackgroundCarbon monoxide (CO) is one of the primary components of emissions from light-duty vehicles, and reportedly comprises 77% of all pollutants emitted in terms of concentration. Exposure to CO aggravates cardiovascular disease and causes other health disorders. The study was aimed to assess the negative effects by injecting different amounts of CO concentration directly to human volunteers boarding in the car.MethodsHuman volunteers were exposed to CO concentrations of 0, 33.2, and 72.4 ppm, respectively during the first test and 0, 30.3, and 48.8 ppm respectively during the second test while seated in the car. The volunteers were exposed to each concentration for approximately 45 min. After exposure, blood pressure measurement, blood collection (carboxyhemoglobin [COHb] analysis), medical interview, echocardiography test, and cognitive reaction test were performed.ResultIn patients who were exposed to a mean concentration of CO for 72.4 ± 1.4 ppm during the first exposure test and 48.8 ± 3.7 ppm during the second exposure test, the COHb level exceeded 2%. Moreover, the diastolic blood pressure was decreased while increasing in CO concentration after exposure. The medical interview findings showed that the degree of fatigue was increased and the degree of concentration was reduced when the exposed concentration of CO was increased.ConclusionAlthough the study had a limited sample size, we found that even a low concentration of CO flowing into a car could have a negative influence on human health, such as change of blood pressure and degree of fatigue.

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Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing

Cited by 27 publications

References 26 publications

Effects of Indoor and Ambient Black Carbon and PM2.5 on Pulmonary Function among Individuals with COPD

Effects of Indoor and Ambient Black Carbon and PM2.5 on Pulmonary Function among Individuals with COPD

Cardiovascular benefits of reducing personal exposure to traffic-related noise and particulate air pollution: A randomized crossover study in the Beijing subway system

Decreased blood pressure associated with in-vehicle exposure to carbon monoxide in Korean volunteers

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