Acute esophageal necrosis and liver pathology, a rare combination

Khan, Amir

doi:10.3748/wjg.v10.i16.2457

Cited by 19 publications

(20 citation statements)

References 19 publications

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“…Antimicrobials are indicated in select patients with signs of sepsis or immunocompromised states [8]. Endoscopy is diagnostic, and timing of follow up endoscopies needs to be dictated by patient's clinical status [9].…”

Section: Discussionmentioning

confidence: 99%

Acute esophageal necrosis: a case series of five patients presenting with “Black esophagus”

Singh¹,

Singh

Laya

2011

Indian J Gastroenterol

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Acute esophageal necrosis (AEN), also known as "Black esophagus", is a rare condition that typically presents as upper gastrointestinal hemorrhage. A retrospective chart analysis was conducted at two tertiary care hospitals over a three-year period (2005-2007) using a computerized inpatient database. Out of 9,179 upper endoscopies performed, five patients (0.05% prevalence) were found to have black esophagus. Their mean age was 44 years and the most common presentation was upper gastrointestinal bleeding. All five patients had comorbid conditions, most commonly coronary artery disease, diabetes mellitus, and renal insufficiency. Two patients died, but the cause of death was not related to AEN in either. In conclusion, AEN is usually seen in critically ill elderly patients with multiple comorbid conditions, particularly vascular disease, diabetes mellitus and azotemia.

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Section: Discussionmentioning

confidence: 99%

Acute esophageal necrosis: a case series of five patients presenting with “Black esophagus”

Singh¹,

Singh

Laya

2011

Indian J Gastroenterol

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“…The appearance of ANE has been associated with hypothermia [1], Peripheral arterial disease [8], Alcohol abuse [9], cirrhosis [10], Diabetic ketoacidosis [7], cholangiocarcinoma [11], malnutrition, nephrotic syndrome [12], DM, hypertension, and NSAID intake [7]. …”

Section: Discussionmentioning

confidence: 99%

Acute Necrotizing Esophagitis Followed by Duodenal Necrosis

Hierro

2011

Gastroenterol Res

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Acute Necrotizing Esophagitis is an uncommon pathology, characterized by endoscopic finding of diffuse black coloration in esophageal mucosa and histological presence of necrosis in patients with upper gastrointestinal bleeding. The first case of acute necrotizing esophagitis followed by duodenal necrosis, in 81 years old woman with a positive history of Type 2 Diabetes Mellitus, Hypertension, and usual intake of Nonsteroidal Anti-inflammatory drugs, is reported. Although its etiology remains unknown, the duodenal necrosis suggests that ischemia could be the main cause given that the branches off the celiac axis provide common blood supply to the distal esophageal and duodenal tissue. The massive gastroesophagic reflux and NSAID intake could be involved.

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“…It has also been referred to as acute necrotizing esophagitis or acute esophageal necrosis and gastrointestinal bleeding is the common clinical manifestation 3,5,6 . The differential diagnosis includes melanosis, pseudo‐melanosis, melanoma, acanthosis nigricans, and caustic substance (lye) ingestion 2,5 . Many of these conditions are suggested by history and histology.…”

Section: Discussionmentioning

confidence: 99%

“…Black esophagus is a rare observation during esophagogastroduodenoscopy (EGD) seen in approximately 0.2% of cases 1 . While the etiology remains unknown, it occurs in elderly patients and/or those with comorbid conditions, 2,3 particularly vascular disorders. It usually involves the distal third of the esophagus, which is less vascularized than the proximal two‐thirds 4 .…”

Section: Introductionmentioning

confidence: 99%

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Black Esophagus: A Case Series

Forman

Gopal

Huysman³

et al. 2007

Digestive Endoscopy

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Black esophagus is a rare endoscopic finding. While the etiology remains unknown, it occurs in elderly patients and/or those with comorbid conditions, particularly vascular disorders. It usually involves the distal third of the esophagus. The most common presenting symptom is acute esophageal bleeding. The natural history of the disease is that of spontaneous resolution. The differential diagnosis includes acute necrotizing esophagitis, melanosis, pseudo-melanosis, melanoma, acanthosis nigricans, and caustic substance (lye) ingestion. Some associated conditions include ischemia, prolonged hypotension, hyperglycemia, hypersensitivity to antibiotics, herpetic infection, aortic dissection, and anti-cardiolipin antibodies. The pathogenesis of black esophagus is not fully understood, but it is hypothesized that low systemic perfusion plays a dominant role. The present report describes three women diagnosed during esophagogastroduodenoscopy with black esophagus. Two of our patients presented with hypertensive emergencies, an association not reported in the literature. One of the patients described developed Gram-negative bacteremia after esophagogastroduodenoscopy, an unreported sequelae of black esophagus.

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Acute esophageal necrosis and liver pathology, a rare combination

Cited by 19 publications

References 19 publications

Acute esophageal necrosis: a case series of five patients presenting with “Black esophagus”

Acute esophageal necrosis: a case series of five patients presenting with “Black esophagus”

Acute Necrotizing Esophagitis Followed by Duodenal Necrosis

Black Esophagus: A Case Series

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