Acute esophageal necrosis: report of two cases and a review of the literature

Acute esophageal necrosis and liver pathology, a rare combination

“…Lacy et al [1] reported a 15% complication rate, whereas other case series have reported very low to none. Recurrence was less than 10% [6,24] and mortality ranged between 0-33% [1,6,25] . The prognosis depends on the patient's general status rather than the extent of local esophageal necrotic lesions.…”

“…Other conditions associated with this disease entity were prolonged hypertension [13] , ischemia [5,14] , hyperglycemia [1] , hypersensitivity to antibiotics [15] , herpetic infection [16] , gastric volvulus [17] , posterior mediastinal haematoma and aortic dissection [3,18] , anti-cardiolipin antibodies [19] and Steven Johnson syndrome [20] . In short, a multi-factorial etiology to absence of any disease (idiopathic) is possible.…”

“…The main reported complications of AEN were esophageal stenosis and stricture formation [1,2] . Lacy et al [1] reported a 15% complication rate, whereas other case series have reported very low to none.…”

“…It has been described only a few times in the past. Lacey et al in 1991 reported 25 cases [1] . A similar report by Benoit et al [2] in 1999 cited 27 cases after an extensive review of the literature.…”

Black Esophagus: An Unusual Finding During Routine Endoscopy

“…All of the patients were severely ill. A variety of mechanisms has been proposed to account for the development of this unusual condition, including prolonged hypotension [6], hyperglycemia [3], hypersensitivity to antibiotics [7], underlying malignancy [3], herpetic infection [4], and an association with gastric volvulus [5]. The case described here is unique because of the absence of any of the above conditions.…”