Acute generalized exanthematous pustulosis induced by ingestion of lacquer chicken

Park, Y.M.; Park, J.G.; Kang, Hyeon Hui; Houh, Dong; Byun, Dae Gyoo; Kim, J.W.

doi:10.1046/j.1365-2133.2000.03643.x

Cited by 22 publications

(20 citation statements)

References 3 publications

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“…Interestingly, chicken broth containing lacquers has been considered to be an alternative medicine for peptic ulcers and as a health food to prevent certain hypersensitivity reactions to lacquers in Korea. Park et al 12 already reported a series of cases of AGEP induced by lacquer chicken in Korean patients. Likewise, all of our patients developed AGEP shortly after ingestion of lacquer as lacquer chicken broth, and then the problem resolved soon after treatment.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathologic Manifestations of 36 Korean Patients with Acute Generalized Exanthematous Pustulosis: A Case Series and Review of the Literature

et al. 2010

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Background: Acute generalized exanthematous pustulosis (AGEP) is a rare and severe subtype of drug eruption, characterized by acute, extensive, non-follicular, sterile pustules on an erythematous background, accompanied by fever and leukocytosis. Objective: The purpose of this study was to characterize AGEP in Korean patients in terms of clinical, laboratory, and pathologic findings. Methods: Thirty-six patients (M:F=17:19) with AGEP were identified from an extensive review of medical records over a 15 year period. All patient cases were confirmed by biopsy and fulfilled the diagnostic criteria. Results: The patient ages ranged from 4∼80 years (37.6±19.4). The incubation period was 1∼23 days. The duration of disease was 5∼14 days. Neutrophilia (36/36), high CRP (14/36), and eosinophilia (30/36) were common laboratory findings. A history of drug administration existed in 23 of 36 patients; herbal medications, lacquers and radiocontrast media were the unique causative drugs. Spongioform subcorneal or intraepidermal pustules in the epidermis was observed in all patients. Thirty-six patients were subdivided into 2 groups: group A (n=23) was strongly associated with known agents; and group B (n=13) had no identified causative agents. There was no significant difference between the 2 groups. Conclusion: Our results demonstrate the characteristic features of AGEP in Korean patients as follows: lower identification of causative agents; herbal medications, lacquers, and radiocontrast media were the main causative agents; and no significant differences existed between the 2 groups. (Ann Dermatol 22(2) 163∼169, 2010)

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Section: Discussionmentioning

confidence: 99%

Clinicopathologic Manifestations of 36 Korean Patients with Acute Generalized Exanthematous Pustulosis: A Case Series and Review of the Literature

et al. 2010

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“…AGEP is mostly due to drugs [2]. Some viruses, mercury or poison ivy have also been reported to cause this eruption [1, 3]. The mechanism of this side effect is poorly understood.…”

Section: Introductionmentioning

confidence: 99%

Acute Generalized Exanthematous Pustulosis Associated with STI571 in a Patient with Chronic Myeloid Leukemia

et al. 2001

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The tyrosine kinase inhibitor STI571 is a novel promising class of anticancer drugs. We report a case of cutaneous adverse reactions to STI571 in a young woman with blast crisis of chronic myeloid leukemia. She had first typical acute generalized exanthematous pustulosis mimicking mercury rash and then urticarial eruption. We suggest that cell pathways mediated by some tyrosine kinases might be involved in the pathogenesis of these skin eruptions.

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“…AGEP very rarely occurs secondary to ingestion of lacquer chicken. To date, four cases have been reported by Park et al 3 . All the patients in their report developed AGEP within one to four days after ingestion of lacquer chicken, and with or without treatment, all the eruptions resolved within ten days.…”

Section: Discussionmentioning

confidence: 99%

“…A wide range of systemic drugs have been suspected of causing these reactions in more than 90% of cases 2 . Rarely, intake of lacquer chicken can be a cause of AGEP, and Park et al 3 reported four such cases. We present a case of AGEP induced by ingestion of lacquer chicken, which contains a known allergen, urushiol.…”

Section: Introductionmentioning

confidence: 99%

Acute Generalized Exanthematous Pustulosisafter Ingestion of Lacquer Chicken

Park

Kang

2008

Ann Dermatol

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Acute generalized exanthematous pustulosis induced by ingestion of lacquer chicken

Cited by 22 publications

References 3 publications

Clinicopathologic Manifestations of 36 Korean Patients with Acute Generalized Exanthematous Pustulosis: A Case Series and Review of the Literature

Clinicopathologic Manifestations of 36 Korean Patients with Acute Generalized Exanthematous Pustulosis: A Case Series and Review of the Literature

Acute Generalized Exanthematous Pustulosis Associated with STI571 in a Patient with Chronic Myeloid Leukemia

Acute Generalized Exanthematous Pustulosisafter Ingestion of Lacquer Chicken

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