Acute Imidacloprid Poisoning Caused Prolong Depression of Butyrylcholinesterase

Lin, Chih-Chuan; Li, Jen-Hou; Chiu, Te-Fa

doi:10.4172/2161-0495.1000261

Cited by 1 publication

(3 citation statements)

References 12 publications

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“…History, circumstantial evidence, and clinical features form the basis for clinical diagnosis of any poisoning including IMI. Currently, there is no specific diagnostic tool/marker available to diagnose IMI poisoning by laboratory tests 21 . Liquid chromatography/mass spectrometry, 10 gas chromatography/mass spectrometry, and high-performance liquid chromatography/photodiode array detector 22 could be used for screening and quantification of IMI compounds.…”

Section: Discussionmentioning

confidence: 99%

“…Currently, there is no specific diagnostic tool/marker available to diagnose IMI poisoning by laboratory tests. 21 Liquid chromatography/mass spectrometry, 10 gas chromatography/mass spectrometry, and high-performance liquid chromatography/ photodiode array detector 22 could be used for screening and quantification of IMI compounds. Biological samples, such as whole blood from the femoral vein, cerebrospinal fluid, vitreous humor, and urine, should be preserved at the time of autopsy.…”

Section: Discussionmentioning

confidence: 99%

“…Decreased level of the butyrylcholinesterase in case 1 should be cautiously interpreted as it may raise the suspicion of organophosphate poisoning. Decreased level of butyrylcholinesterase may also reportedly present in IMI poisoning 21 because of laboratory error, chronic exposure to organophosphate compound, ingestion of large-dose IMI, liver cirrhosis, malnutrition, and idiosyncratic reaction. 21 Because the quantity of ingested IMI was unknown in case 1, the possibility of large-dose IMI-induced depression of butyrylcholinesterase could not be ruled out.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Self-Poisoning With Safer Insecticide

Naveen¹,

Sahu²,

Padhi³

et al. 2021

Am J Forensic Med Pathol

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Imidacloprid (IMI) is a systemic insecticide that belongs to the neonicotinoid group of insecticides. It is highly effective against sucking, boring, and root-feeding insects. Besides, it has a favorable toxicological profile on humans. Currently, IMI is the largest selling insecticide in the world by replacing organophosphates and carbamates. It acts as nicotinic acetylcholine receptor agonist in the central nervous system of insects. To date, there is no specific antidote available for IMI poisoning. Despite a better safety profile on humans, severe toxicity from IMI poisoning is not uncommon. Here, we report a series of 4 cases who were admitted to our tertiary care center with a history of IMI poisoning.

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Section: Discussionmentioning

confidence: 99%