Acute iron poisoning in adult female

Skoczyńska, Anna; Kwiecinska, D; Kiełbiński, Marek; Łukaszewski, Marceli

doi:10.1177/0960327107071854

Cited by 19 publications

(23 citation statements)

References 14 publications

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“…In our case deferrioxamine treatment was not given because serum iron level of the patient was not higher than 500μg/dL. 1,3 The patient whom vital findings were stable was discharged after 48hours.…”

Section: Discussionmentioning

confidence: 86%

“…The liver is one of the organs most affected by cellular iron toxicity, but other organs such as the heart, kidneys, lungs, and the hematologic systems may also be impaired. 1,2 With both corrosive and cellular toxicity, the end result is significant metabolic acidosis, due to several factors. Hypoper fusion due to significant volume loss, vasodilatation, and negative inotropic effect of iron will result in lactic acidosis.…”

Section: Discussionmentioning

confidence: 99%

“…Acute iron poisoning can cause serious complications resulting in death. 1,2 The severity of poisoning depends on the amount of iron intake. If intake of elementary iron is below 20mg/kg, the risk of toxicity is low, decontamination and at least 6hours observation is recommended.…”

Section: Introductionmentioning

confidence: 99%

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Acute Iron Poisoning: A Case Report

Yeşiler¹

2018

MOJCR

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In adults, the common cause of iron poisoning is iron overload caused by large excess of iron supplement in take at suicidal attemps. When serum iron level exceeds the iron binding capacity of the body, free radicals occur, leading to lipid peroxidation and cellular membrane damage. In iron poisoning, most affected organs are liver, heart, kidney and lungs. Also hematologic system is affected negatively. Acute iron poisoning can cause serious complications resulting in death. The treatment scheme is determined by the type of iron preparation, time of intake, and the onset of symptoms. Initial treatment approaches mostly consist of supportive care and removal of iron with bowel irrigation. 1-3 Early treatment and close follow-up in intensive care unit are important for acute iron poisoning. In this case report, we examined the approach to a case of acute iron poisoning with moderated oseiron intake for suicide attempt.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

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Acute Iron Poisoning: A Case Report

Yeşiler¹

2018

MOJCR

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“…Serum demir düzeyi vücudun bağlama kapasitesini aştığında serbest radikaller oluşur ve lipid peroksidasyonu ile hücre yıkımı meydana gelir. Demir zehirlenmesinde karaciğer başta olmak üzere, kalp, böbrek, akciğerler ve hematolojik sistem olumsuz etkilenir (1)(2)(3).…”

Section: Gi Riflunclassified

Akut Demir Zehirlenmesine Yaklaşım: Olgu Sunumu

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2011

tybdd

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Yetişkinlerde demir zehirlenmesinin esas nedeni intihar girişimleri ve gebelik sırasında aşırı dozda demir alımıdır. İntoksikasyonun şiddeti alınan demir miktarına bağlıdır. Serum demir düzeyi vücudun bağlama kapasitesini aştığında serbest radikaller oluşur ve lipid peroksidasyonu ile hücre yıkımı meydana gelir. Demir zehirlenmesinde karaciğer başta olmak üzere, kalp, böbrek, akciğerler ve hematolojik sistem olumsuz etkilenir. Akut demir zehirlenmesi ölümle sonuçlanabilecek ciddi komplikasyonlara yol açabileceğinden klinik ve laboratuar takip ile birlikte erken tedavi önem taşımaktadır. Bu olgu sunumunda, suisid amacıyla yüksek doz demir alımına bağlı gelişen akut demir zehirlenmesine yaklaşımı inceledik. (Türk Yo €un Ba k›m Der ne €i Der gi si 2011; 9: 107-9) Anah tar Ke li me ler: Akut demir zehirlenmesi, yoğun bakım ÖZET SUMMARYIn adults, the main causes of iron poisoning are intake suicide attempts and an overdose of iron during pregnancy. The severity of intoxication depends on the amount of iron. When serum iron level exceeds the iron binding capacity of the body, free radicals occurs, leading to lipid peroxidation and cellular membrane damage. In iron poisoning, especially the liver, heart, kidney, lung, and hematologic systems are affected negatively. Acute iron poisoning can cause serious complications resulting in death. Clinical, laboratory observation and early treatment are important. In this case report, we examined to approach the acute iron poisoning with the occasion of high-dose iron intake for suicide attempt. (Journal of the Turkish Society Intensive Care 2011; 9: 107-9)

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“…Em humanos, a sua carência pode causar anemia ferropriva e outras disfunções. Mas em quantidades elevadas, o ferro pode ser tóxico (CORBETT, 1995;BALMADRID e BONO, 2009), já que quando metabolizado excessivamente, afeta quase todos os órgãos humanos, em função de sua toxicidade intracelular sistêmica, podendo aumentar a incidência de problemas cardía-cos e diabetes (ROBERTSON e TENENBEIN, 2006;SKOCZYNSKA et al, 2007). Devlin (2007) afirma que o acúmulo excessivo de ferro no fígado, no pâncreas e no coração pode levar a cirrose e tumores hepáticos, Diabetes mellitus e insuficiência cardíaca, respectivamente.…”

Section: Introductionunclassified