Acute Laryngeal Dystonic Reactions to Neuroleptics

Koek, Ralph J.; Pi, Edmond H.

doi:10.1016/s0033-3182(89)72240-4

Cited by 45 publications

(23 citation statements)

References 18 publications

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“…Male gender, rapid titration of dose, and use of highpotency agents probably increases the risk. Respiratory compromise from neuroleptics can be a frightening entity, with acute dystonia affecting the larynx or pharynx causing stridor and even acute airway closure [33]. Tardive respiratory dyskinesias can also be a life-threatening event.…”

Section: Tardive and Neuroleptic-induced Emergenciesmentioning

confidence: 99%

Treatment of Movement Disorder Emergencies

Frucht

2014

Neurotherapeutics

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Movement disorder emergencies are defined as clinical scenarios where a movement disorder develops over hours to days, and in which morbidity and even mortality can result from failure to appropriately diagnose and manage the patient. The last decade has seen increasing recognition of various movement disorder emergencies, including acute parkinsonism, neuroleptic malignant syndrome, respiratory compromise in multiple system atrophy, dystonic storm, oculogyric crisis, and hemiballism, among others. This article will review the major movement disorder emergencies encountered in the hospital and office, emphasizing practical management and treatment.

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Section: Tardive and Neuroleptic-induced Emergenciesmentioning

confidence: 99%

Treatment of Movement Disorder Emergencies

Frucht

2014

Neurotherapeutics

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“…Koek and Pi [68] reviewed nine cases of acute laryngeal dystonia (laryngospasm following exposure to neuroleptics) of which six patients were young men (under 30 years old), and all episodes of laryngospasm occurred within 8 days of initiating treatment. Most patients received only a modest dose, suggesting that there may be individuals with a heightened susceptibility to develop acute dystonia.…”

Section: Acute Laryngeal Dystoniamentioning

confidence: 99%

Movement disorder emergencies

Poston

Frucht

2008

J Neurol

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Movement disorder emergencies include any movement disorder which evolves over hours to days, in which failure to appropriately diagnose and manage can result in patient morbidity or mortality. It is crucial that doctors recognize these emergencies with accuracy and speed by obtaining the proper history and by being familiar with the phenomenology of frequently encountered movements. These disorders will be discussed based on the most common associated involuntary movement, either parkinsonism, dystonia, chorea, tics or myoclonus, and, when available, review the workup and treatment options based on the current literature.

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“…Flaherty and Lahmeyer [51] were the first to suggest that sudden death following treatment with phenothiazines might occur from acute laryngeal dystonia. Koek and Pi [52] reviewed nine cases of acute laryngeal dystonia (laryngospasm following exposure to neuroleptics). Six patients were young men (under the age of 30 years), and all episodes of laryngospasm occurred within 8 days of initiating treatment.…”

Section: Acute Laryngeal Dystoniamentioning

confidence: 99%

Movement disorder emergencies

Frucht

2005

Curr Neurol Neurosci Rep

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For the past 4 years, Dr. Stanley Fahn and I have given a course at the American Academy of Neurology annual meeting on the topic of movement disorder emergencies. The purpose of this review article is to summarize the topic and to present it to readers of this journal. The text of this article has appeared in nearly the same form as the Academy syllabus accompanying our course. It is being presented here so that readers of the journal may review the material.

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Acute Laryngeal Dystonic Reactions to Neuroleptics

Cited by 45 publications

References 18 publications

Treatment of Movement Disorder Emergencies

Treatment of Movement Disorder Emergencies

Movement disorder emergencies

Movement disorder emergencies

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