Acute Macular Neuroretinopathy

Bos, P. J. M.; Deutman, August F.

doi:10.1016/0002-9394(75)90387-6

Cited by 243 publications

(172 citation statements)

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“…2-4 It was subsequently described with multifocal inner choroidopathy, or pseudo presumed ocular histoplasmosis syndrome, 5 , 6 and acute macular neuroretinopathy. 7 We describe 7 patients who presented to Moorfields Eye Hospital between December 1989 and April 1993 who developed visual loss not explained by fundus find ings associated with multifocal fundus lesions resembling punctate inner choroidopathy.…”

mentioning

confidence: 99%

Acute zonal occult outer retinopathy (AZOOR) associated with multifocal choroidopathy

Holz

Kim

Schwartz

et al. 1994

Eye

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confidence: 99%

Acute zonal occult outer retinopathy (AZOOR) associated with multifocal choroidopathy

Holz

Kim

Schwartz

et al. 1994

Eye

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“…Acute pigment epi thelitis [1]. acute multifocal placoid pigment epitheliopathy [2] and acute macular retino pathy [10] have been suggested as being in flammatory lesions, the etiology and patho genesis of which, however, has not been established. Clinical observations [11] point an infectious process and viruses have been claimed to be the causative agents [12].…”

Section: Discussionmentioning

confidence: 99%

Virus-Induced Pigment Epithelitis in Rhesus Monkeys

Krey¹,

Stitz

Ludwig

1982

Ophthalmologica

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“…A cute macular neuroretinopathy was first discribed by Bos and Deutmann in 1975 and is a rare uni-or bilateral maculopathy of unknown etiology involving mainly young women between the ages of 20 and 30 years. Most patients experience sudden onset of paracentral scotomas with preserved good visual acuity, often with a preceding flu-like disease (Bos & Deutmann 1975;Miller et al 1989).…”

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confidence: 99%

“…Most patients experience sudden onset of paracentral scotomas with preserved good visual acuity, often with a preceding flu-like disease (Bos & Deutmann 1975;Miller et al 1989). Ophthalmoscopy shows wedgeshaped, red-brown lesions arranged radially in the macula.…”

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Optical coherence tomography (OCT) in acute macular neuroretinopathy

Feigl

Haas

2000

Acta Ophthalmologica Scandinavica

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ABSTRACT.Purpose: To evaluate the value of ocular coherence tomography (OCT) concerning diagnosis and pathogenesis of acute macular neuroretinopathy. Methods: A 33-year old woman complained of sudden onset of central scotomas in her right eye because of acute macular neuroretinopathy. We performed a direct ophthalmoscopy, a visual field testing, a fluorescein angiography (FA) a multifocal ERG (mf-ERG) and an OCT. Results: We found typical paracentral scotoma in visual field testing, a normal FA and mf-ERG in her right eye. In OCT there was a band of higher reflectivity (115 mm) overlying an intact band corresponding to the retinal pigment epithelium (RPE)/ choriocapillaris complex. Retinal thickness was within the normal range. Conclusion: OCT can be an additional valuable tool in acute macular neuroretinopathy as it is a disease with discrete pathology and often normal results in other diagnostic tests. A cute macular neuroretinopathy was first discribed by Bos and Deutmann in 1975 and is a rare uni-or bilateral maculopathy of unknown etiology involving mainly young women between the ages of 20 and 30 years. Most patients experience sudden onset of paracentral scotomas with preserved good visual acuity, often with a preceding flu-like disease (Bos & Deutmann 1975;Miller et al. 1989). Ophthalmoscopy shows wedgeshaped, red-brown lesions arranged radially in the macula. The lesions are suggested to be located in the outer retina, FA and standard electroretinography (Sieving et al. 1984) typically are normal, whereas Amsler grid and visual fields reveal parafoveal scotomas. Visual deficit does not improve as persistance of maculopathy and scotomas have been described up to 9 years (Desai et al.1993) and a benefit of any medical treatment (e.g steroids) has not been proven to date. Case ReportA 33-year-old female patient complained about sudden visual disturbances with central, greyish, swirling scotomas on her right eye. A week before she had suffered from a flu-like disease with fever, swelling of the left submandibular lymph nodes, and pain in her joints. Other than taking oral antibiotics after the onset of visual problems, she did not receive any treatment.Visual acuity was 20/20 on her right eye; on her left eye she had a decreased visual acuity (20/100) because of squinting as a child and amblyopia. Amsler grid examination showed metamorphopsia in the temporal superior area on her right eye. Direct ophthalmoscopy revealed red-brown lesions (Fig. 1) in the macula area and visual field testing (Octopus M2, Interzeag, Switzerland) showed paracentral scotomas (Fig. 2) while the results on her left eye were within the normal range. First order Kernels of mf-ERG (Reti scan, Roland Consult, Wiesbaden, Germany) were normal

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Acute Macular Neuroretinopathy

Cited by 243 publications

References 5 publications

Acute zonal occult outer retinopathy (AZOOR) associated with multifocal choroidopathy

Acute zonal occult outer retinopathy (AZOOR) associated with multifocal choroidopathy

Virus-Induced Pigment Epithelitis in Rhesus Monkeys

Optical coherence tomography (OCT) in acute macular neuroretinopathy

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