Acute myocardial infarction: susceptibility-weighted cardiac MRI for the detection of reperfusion haemorrhage at 1.5 T

Durighel, Giuliana; Tokarczuk, Pawel; Karsa, Anita; Gordon, Fabiana; Cook, Stuart A.; O’Regan, Declan P

doi:10.1016/j.crad.2015.12.008

Cited by 5 publications

(7 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The weighted mean T 2 * values at 1.5 T in myocardial infarction (MI) patients was 28.5 ± 6.8 ms and 34.7 ± 3.7 ms in controls [39][40][41][42][43][44][45][46][47][48][49] (Table 1, Fig. 2).…”

Section: Myocardial Infarctionmentioning

confidence: 99%

“…4). Most studies performed CMR in ST-elevation myocardial infarction (STEMI) patients post percutaneous coronary intervention (PCI) in the acute phase [39][40][41][42][43][44][46][47][48][49][50][51]. Some studies performed follow-up in these patient groups [42-44, 47, 49, 50] and Mohammadzadeh et al [45] was the only study including non-STEMI (NSTEMI) patients.…”

Section: Myocardial Infarctionmentioning

confidence: 99%

See 1 more Smart Citation

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Snel

Boomen

Hernández

et al. 2020

Journal of Cardiovascular Magnetic Resonance

View full text Add to dashboard Cite

Background: The clinical application of cardiovascular magnetic resonance (CMR) T 2 and T 2 * mapping is currently limited as ranges for healthy and cardiac diseases are poorly defined. In this meta-analysis we aimed to determine the weighted mean of T 2 and T 2 * mapping values in patients with myocardial infarction (MI), heart transplantation, non-ischemic cardiomyopathies (NICM) and hypertension, and the standardized mean difference (SMD) of each population with healthy controls. Additionally, the variation of mapping outcomes between studies was investigated. Methods: The PRISMA guidelines were followed after literature searches on PubMed and Embase. Studies reporting CMR T 2 or T 2 * values measured in patients were included. The SMD was calculated using a random effects model and a meta-regression analysis was performed for populations with sufficient published data. Results: One hundred fifty-four studies, including 13,804 patient and 4392 control measurements, were included. T 2 values were higher in patients with MI, heart transplantation, sarcoidosis, systemic lupus erythematosus, amyloidosis, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM) and myocarditis (

show abstract

Section: Myocardial Infarctionmentioning

confidence: 99%

Section: Myocardial Infarctionmentioning

confidence: 99%

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Snel

Boomen

Hernández

et al. 2020

Journal of Cardiovascular Magnetic Resonance

View full text Add to dashboard Cite

show abstract

“…However, we did find a difference in the T 1Core and T 2Core between those with early MVO with IMH and early MVO without IMH and this needs to be confirmed in future studies. We did not acquire data on black blood T 2 ‐STIR images or susceptibility‐weighted cardiac MRI (which has been shown to improve the detection of IMH at 1.5 T and 3T for comparison. The reduction in T 1 and T 2 using SSFP readouts could have been due to a combination of both the on‐resonance and off‐resonance signals from the paramagnetic components of the IMH and this was not elucidated in this study.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic performance of T₁ and T₂ mapping to detect intramyocardial hemorrhage in reperfused ST‐segment elevation myocardial infarction (STEMI) patients

Bulluck

Rosmini

Abdel‐Gadir

et al. 2017

Magnetic Resonance Imaging

View full text Add to dashboard Cite

PurposeTo investigate the performance of T 1 and T 2 mapping to detect intramyocardial hemorrhage (IMH) in ST‐segment elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PPCI).Materials and MethodsFifty STEMI patients were prospectively recruited between August 2013 and July 2014 following informed consent. Forty‐eight patients completed a 1.5T cardiac magnetic resonance imaging (MRI) with native T 1, T 2, and T2* maps at 4 ± 2 days. Receiver operating characteristic (ROC) analyses were performed to assess the performance of T 1 and T 2 to detect IMH.ResultsThe mean age was 59 ± 13 years old and 88% (24/48) were male. In all, 39 patients had interpretable T2* maps and 26/39 (67%) of the patients had IMH ( T2* <20 msec on T2* maps). Both T 1 and T 2 values of the hypointense core within the area‐at‐risk (AAR) performed equally well to detect IMH (T 1 maps AUC 0.86 [95% confidence interval [CI] 0.72–0.99] versus T 2 maps AUC 0.86 [95% CI 0.74–0.99]; P = 0.94). Using the binary assessment of presence or absence of a hypointense core on the maps, the diagnostic performance of T 1 and T 2 remained equally good (T 1 AUC 0.87 [95% CI 0.73–1.00] versus T 2 AUC 0.85 [95% CI 0.71–0.99]; P = 0.90) with good sensitivity and specificity (T 1: 88% and 85% and T 2: 85% and 85%, respectively).ConclusionThe presence of a hypointense core on the T 1 and T 2 maps can detect IMH equally well and with good sensitivity and specificity in reperfused STEMI patients and could be used as an alternative when T2* images are not acquired or are not interpretable. Level of Evidence: 2 Technical Efficacy: Stage 2J. MAGN. RESON. IMAGING 2017;46:877–886

show abstract

“…In our study, we designed different extend MI from 9.5% to 46.9%. This infarction extent was bigger than in former studies [2,7,[9][10][11][12][13][14][15][16][17][18][19][20]; the range of these studies was not comprehensive to reveal the relationship between IMH and MI. Some areas in our study were smaller than the other study, this suggested that IMH can be found in small MI sizes.…”

Section: Discussionmentioning

confidence: 56%

Myocardial Infarction as An Independent Predictor of Intramyocardial Hemorrhage in Acute Reperfused Myocardial Ischemic Rats

Xia¹,

Tong²,

Zhang³

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: In the previous studies, hemorrhage occurred only with the largest infarctions and studies confirmed a moderate correlation between the extent of necrosis and hemorrhage, but the extent of infarction size of these studies was limited. This study was to find the correlations between intramyocardial hemorrhage (IMH), myocardial infarction (MI), and myocardial edema (ME) from days 2 to 7 in a 7.0T MR scanner.Methods: The different degrees of myocardial ischemia were induced by occluding different sections of the proximal left anterior descending coronary artery (1–3 mm under the left auricle). T2*-mapping, T2-mapping and late gadolinium enhancement (LGE) sequences were performed on a 7.0T MR system at day 2 and 7. T2*- and T2-maps were calculated using a custom-made software. All areas were expressed as a percentage of the whole myocardial tissue of the left ventricle. The rats were divided into two groups based on the T2* results; MI with IMH was referred to as the +IMH group, while MI without IMH was referred to as the –IMH group.Results: The final experimental sample consisted of 25 rats in the +IMH group and 10 rats in the –IMH group. For the +IMH group. On day 2, There was a significant positive correlation between IMH size and MI size (r = 0.677, P<0.01), and a positive correlation between IMH size and ME size (r = 0.552, P<0.01). On day 7, There was a significant positive correlation between IMH size and MI size (r = 0.711, P<0.01), while no correlation was found between IMH size and ME size (r = 0.429, P = 0.097). Conclusions: Infarction size prior to reperfusion is a critical factor in determining whether a MI is hemorrhagic or non-hemorrhagic in rats.

show abstract

Acute myocardial infarction: susceptibility-weighted cardiac MRI for the detection of reperfusion haemorrhage at 1.5 T

Cited by 5 publications

References 29 publications

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Diagnostic performance of T₁ and T₂ mapping to detect intramyocardial hemorrhage in reperfused ST‐segment elevation myocardial infarction (STEMI) patients

Myocardial Infarction as An Independent Predictor of Intramyocardial Hemorrhage in Acute Reperfused Myocardial Ischemic Rats

Contact Info

Product

Resources

About

Acute myocardial infarction: susceptibility-weighted cardiac MRI for the detection of reperfusion haemorrhage at 1.5 T

Cited by 5 publications

References 29 publications

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Cardiovascular magnetic resonance native T2 and T2* quantitative values for cardiomyopathies and heart transplantations: a systematic review and meta-analysis

Diagnostic performance of T1 and T2 mapping to detect intramyocardial hemorrhage in reperfused ST‐segment elevation myocardial infarction (STEMI) patients

Myocardial Infarction as An Independent Predictor of Intramyocardial Hemorrhage in Acute Reperfused Myocardial Ischemic Rats

Contact Info

Product

Resources

About

Diagnostic performance of T₁ and T₂ mapping to detect intramyocardial hemorrhage in reperfused ST‐segment elevation myocardial infarction (STEMI) patients