Acute phase protein response in Alpine ibex with sarcoptic mange

Rahman, Md. Mizanur; Lecchi, Cristina; Fraquelli, C.; Sartorelli, P.; Ceciliani, Fabrizio

doi:10.1016/j.vetpar.2009.12.001

Cited by 50 publications

(49 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No other reports of APP concentrations in rodents affected by scabies have been found in literature. However, in a study performed in Alpine ibexes with sarcoptic mange, the authors found a greater than 10-fold increase for ASG and between a twofold and fivefold increase for Hp (Rahman et al, 2010), indicating that scabies induces an acute phase response in animals.…”

Section: Acute Phase Response In Animals With Scabiesmentioning

confidence: 92%

Acute Phase Protein Response in the Capybara (Hydrochoerus Hydrochaeris)

Bernal

Feser

Martı́nez-Subiela

et al. 2011

Journal of Wildlife Diseases

View full text Add to dashboard Cite

ABSTRACT:We evaluated the acute phase protein response in capybaras (Hydrochoerus hydrochaeris). Three animal groups were used: 1) healthy animals (n530), 2) a group in which experimental inflammation with turpentine was induced (n56), and 3) a group affected with sarcoptic scabies (n514) in which 10 animals were treated with ivermectin. Haptoglobin (Hp), acid-soluble glycoprotein (ASG) and albumin were analyzed in all animals. In those treated with turpentine, Hp reached its maximum value at 2 wk with a 2.7-fold increase, whereas ASG increased 1.75-fold and albumin decreased 0.87-fold 1 wk after the induction of inflammation. Capybaras affected with sarcoptic scabies presented increases in Hp and ASG of 4.98-and 3.18-fold, respectively, and a 0.87-fold decrease in albumin, compared with healthy animals. Haptoglobin and ASG can be considered as moderate, positive acute phase proteins in capybaras because they showed less than 10-fold increases after an inflammatory process and reached their peak concentrations 1 wk after the induction of inflammation. Conversely, albumin can be considered a negative acute phase protein in capybaras because it showed a reduction in concentration after inflammatory stimulus.

show abstract

Section: Acute Phase Response In Animals With Scabiesmentioning

confidence: 92%

Acute Phase Protein Response in the Capybara (Hydrochoerus Hydrochaeris)

Bernal

Feser

Martı́nez-Subiela

et al. 2011

Journal of Wildlife Diseases

View full text Add to dashboard Cite

show abstract

“…The measure of APPs has been shown to not imply any advantage against the traditional markers observed for the diagnosis of pregnancy toxemia (González et al, 2011). Moreover, an increase of several APPs has been observed in the Alpine ibex with sarcoptic mange (Rahman et al, 2010), which probably would act in the same way in domestic goats.…”

Section: Introductionmentioning

confidence: 99%

Clinicobiochemical investigations of gangrenous mastitis in does: immunological responses and oxidative stress biomarkers

El-Deeb

2013

J. Zhejiang Univ. Sci. B

View full text Add to dashboard Cite

Abstract:A total of 50 does were used to determine selected hematological and biochemical parameters with special references to oxidative stress markers, acute phase protein profiles, and proinflammatory cytokines in healthy and gangrenous mastitis affected does. Animals were divided into two equal groups represented as clinically healthy (control) and diseased groups, respectively. The bacteriological examination of milk samples from diseased does revealed many types of bacterial infection. The isolated bacteria were Staphylococcus aureus (N=23/25), Escherichia coli (N=11/25), and Clostridium perfringens (N=4/25). There was a significant increase in the levels of β-hydroxybutyrate, non-esterified free fatty acids, triglyceride, low density lipoprotein cholesterol (LDL-C), aspartate aminotransferase, and alanine aminotransferase and a significant reduction in the levels of glucose, cholesterol, and high density lipoprotein cholesterol (HDL-C) in does with gangrenous mastitis compared to healthy does. Moreover, there was a significant increase in the levels of malondialdehyde and uric acid with a significant decrease in the levels of reduced glutathione, super oxide dismutase, and catalase in does with gangrenous mastitis compared to healthy does. In addition, there was a significant increase in the haptoglobin, serum amyloid A, fibrinogen, interleukin 6 (IL-6), IL-1β, and tumor necrosis factor-α (TNF-α) in does with gangrenous mastitis compared to healthy ones. Conclusively, oxidative stress biomarkers, acute phase proteins, and proinflammatory cytokines play an essential task as biomarkers for gangrenous mastitis in does. Mastitis may be considered as one of the ketotic stressors in does after parturition.

show abstract

“…In this species SAA and AGP acted as major APPs, whereas Hp and ceruloplasmin acted as moderate APPs, and it has been suggested that APPs could be used for the identification of subclinically infected animals and thus reduce the possibility that these animals are introduced in healthy populations [258].…”

mentioning

confidence: 99%