Acute Physiology and Chronic Health Evaluation (APACHE II) and Glasgow Coma Scores as predictors of outcome from intensive care after cardiac arrest

Niskanen, Minna; Kari, A.; Nikki, P.; Iisalo, E; Kaukinen, L.; Rauhala, V.; Saarela, E; Halinen, Matti

doi:10.1097/00003246-199112000-00005

Cited by 96 publications

(40 citation statements)

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“…6,8,9 Postarrest factors such as high Acute Physiology and Chronic Health Evaluation II or low Glasgow Coma Scale scores are associated with death after initially successful resuscitation. 10 However, most of these studies were conducted within a single center, contained small numbers of arrests, or used data from unblinded and retrospective medical record review. Therefore, it is not surprising that some of the studies have conflicting results.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, it is not surprising that some of the studies have conflicting results. Several studies 8,[10][11][12] have combined various prearrest, arrest, and postarrest factors into clinical decision rules for predicting survival following cardiac arrest. However, because the probability of survival from inhospital cardiac arrest in most studies is less than 20%, a decision rule will not change management unless it can confidently predict the likelihood of survival to be nil.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Derivation of a Clinical Decision Rule for the Discontinuation of In-Hospital Cardiac Arrest Resuscitations

Walraven¹,

Forster²,

Stiell³

1999

Arch Intern Med

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Derivation of a Clinical Decision Rule for the Discontinuation of In-Hospital Cardiac Arrest Resuscitations

Walraven¹,

Forster²,

Stiell³

1999

Arch Intern Med

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“…Data relating to clinical phenotype, risk factors, diagnostic and therapeutic interventions were noted and analyzed subsequently. Disease severity was assessed by Acute Physiology and Chronic Health Evaluation (APACHE) 17 scoring system and available contrast-enhanced computed tomography scan reports (if any).…”

Section: Methodsmentioning

confidence: 99%

Demographic profile of Acute Pancreatitis in Eastern India: A Single Centre Experience

et al. 2017

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Background: Little is known about the etiological risk factors of acute pancreatitis (AP) in Eastern India. Aims and Objective: The aim of this study is to assess current trends etiology of AP in Eastern India. Materials and Methods: A retrospective study with cross-sectional design was undertaken based on available medical records of patients admit between January 2014 and January 2017 with physician-assigned diagnoses of AP at KPC Medical College & Hospital, Kolkata (n = 234). Multivariate analyses were done to identify risk factors, and distribution was compared on the basis gender. Groups were selected on the basis of a working diagnosis. A stratified comparison was done in 3 commonest etiology groups identified: ‘alcohol’, ‘non-alcohol’ and ‘idiopathic’.Results: The commonest etiology was attributed to alcohol (29.4%), idiopathic cause (20.5%), and obstructive cause (14.5%). Prevalence of AP was higher with alcoholism in men (37% vs. 10.8%; p < 00.1), however, other causes like idiopathic cause (12.3% vs. 37.8%), duct obstruction (1.2% vs. 43.2%), obesity (6.1% vs. 24.3%), and hypertriglyceridemia (6.1% vs. 14.8%) were higher among females ( p < 0.001 for all comparisons). Compared to non-alcoholics, patients with idiopathic AP were more likely to be overweight ( p = 0.019) and have T2 DM ( p = 0.021). Moreover, impact assessment of T2 DM status further revealed that the risk of AP was even greater with obesity (Odds Ratio [OR] 1.37; 95% Confidence Interval [CI] 0.57 – 3.26; p = 0.047) and smoking (OR 1.72; 95% CI 1.0 – 2.97; p = 0.049). Eighteen cases (7.7%) of ‘severe’ AP were identified, mostly due to: trauma in 6 (2.5%), idiopathic in 6 (2.5%), gallstones in 4 (1.7%), and alcoholism in 2 (0.8%).Conclusion: Alcohol intake is the predominant etiological risk factor for acute pancreatitis in Eastern India. Gender and type 2 diabetes mellitus are important contributory determinants.Asian Journal of Medical Sciences Vol.8(6) 2017 24-29

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“…The SAPS II score was higher in patients with poor neurological outcome or those who died during their ICU stay than in the [27,28]. Conversely, the highest extracerebral SOFA score at 72 h after CA was independently associated with in-hospital mortality [8].…”

Section: Discussionmentioning

confidence: 89%

APACHE II Score Immediately after Cardiac Arrest as a Predictor of Good Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients Receiving Targeted Temperature Management

Kim¹,

Kim²,

Lee³

et al. 2018

Acute Crit Care

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Background: We used data from a large international database to assess the incidence and impact of extracerebral organ dysfunction on prognosis of patients admitted after cardiac arrest (CA). Methods: This was a sub-analysis of the Intensive Care Over Nations (ICON) database, which contains data from all adult patients admitted to one of 730 participating intensive care units (ICUs) in 84 countries from 8-18 May 2012, except admissions for routine postoperative surveillance. For this analysis, patients admitted after CA (defined as those with "post-anoxic coma" or "cardiac arrest" as the reason for ICU admission) were included. Data were collected daily in the ICU for a maximum of 28 days; patients were followed up for outcome data until death, hospital discharge, or a maximum of 60 days in-hospital. Favorable neurological outcome was defined as alive at hospital discharge with a last available neurological Sequential Organ Failure Assessment (SOFA) subscore of 0-2. Results: Among the 469 patients admitted after CA, 250 (53 %) had had out-of-hospital CA; 210 (45 %) patients died in the ICU and 357 (76 %) had an unfavorable neurological outcome. Non-survivors had a higher incidence of renal (43 vs. 16 %), cardiovascular (56 vs. 45 %), and respiratory (62 vs. 48 %) failure on admission and during the ICU stay than survivors (all p < 0.05). Similar results were found for patients with unfavorable vs. favorable neurological outcomes. In multivariable analysis, independent predictors of ICU mortality were renal failure on admission, high admission Simplified Acute Physiology Score (SAPS) II, high maximum serum lactate levels within the first 24 h after ICU admission, and development of sepsis. Independent predictors of unfavorable neurological outcome were mechanical ventilation on admission, high admission SAPS II score, and neurological dysfunction on admission. Conclusions: In this multicenter cohort, extracerebral organ dysfunction was common in CA patients. Renal failure on admission was the only extracerebral organ dysfunction independently associated with higher ICU mortality.

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Acute Physiology and Chronic Health Evaluation (APACHE II) and Glasgow Coma Scores as predictors of outcome from intensive care after cardiac arrest

Cited by 96 publications

References 0 publications

Derivation of a Clinical Decision Rule for the Discontinuation of In-Hospital Cardiac Arrest Resuscitations

Derivation of a Clinical Decision Rule for the Discontinuation of In-Hospital Cardiac Arrest Resuscitations

Demographic profile of Acute Pancreatitis in Eastern India: A Single Centre Experience

APACHE II Score Immediately after Cardiac Arrest as a Predictor of Good Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients Receiving Targeted Temperature Management

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