Acute pulmonary embolism leading to cavitation and large pulmonary abscess: A rare complication of pulmonary infarction

Koroscil, Matthew; Hauser, Timothy

doi:10.1016/j.rmcr.2016.12.001

Cited by 14 publications

(10 citation statements)

References 4 publications

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“…By contrast, pulmonary cavitary lesions are usually associated with mycobacterial diseases, fungal or parasitic infections, malignancies or autoimmune disorders [ 16 , 17 ]. Although the exact origin of the giant lung cavitation in our patient was not confirmed, diffuse alveolar damage, intra-alveolar haemorrhage and parenchymal necrosis associated with COVID-19 pneumonia can be explanatory factors [ 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Giant cavity pulmonary lesion and pneumothorax following COVID-19 pneumonia

Jafari¹,

Cegolon²,

Masghsoudi³

et al. 2021

Radiology Case Reports

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Cavitary lung formation with spontaneous pneumothorax has been rarely reported as a complication of COVID-19 pneumonia. We report a rare case of a 38 years-old male patient affected by COVID-19 pneumonia, exceptionally complicated by a simultaneous giant cavity in the right upper lung and a small right pneumothorax in the right hemithorax. Whilst pneumothorax emphysema, giant bullae and pneumothorax with alveolar rupture are known to potentially develop in COVID-19 patients as a result of high-flow O 2 support, the exact origin of the giant lung cavitation in our patient could be not confirmed. Cavitary lesions – featured by high mortality rate - are reportedly associated with lung infarctions and can be the aftermaths of pulmonary embolism, a rather common sequela of COVID-19 pneumonia. Radiological imaging is critical to support clinical decision making in the management of COVID-19 pneumonia, since not only it can visualize and stage the disease, but it can also detect and monitor the eventual onset of complications over time, even following patient discharge from hospital.

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Section: Discussionmentioning

confidence: 99%

Simultaneous Giant cavity pulmonary lesion and pneumothorax following COVID-19 pneumonia

Jafari¹,

Cegolon²,

Masghsoudi³

et al. 2021

Radiology Case Reports

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“…Risk factors for destructive changes in the lung tissue against infarct pneumonia are a large infarct zone (>4 cm), older age, presence of heart failure or chronic lung disease. The probability of cavity formation is increased when infarction zone is infected or PE occurs against an infectious disease, often caused by gram-negative flora [7 , 13 , 14] . In the presented clinical case, there was a combination of 2 risk factors for cavitation in PE: multiple massive zones of pulmonary parenchyma infarction (>4 cm) and concomitant Salmonella sepsis.…”

Section: Discussionmentioning

confidence: 99%

Salmonella sepsis in a patient with TLR4 gene polymorphisms

Strutynskaya¹,

Карнаушкина

Tyurin

et al. 2020

Radiology Case Reports

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Non-typhoid Salmonella gastroenteritis is one of the most common forms of intestinal infections among the population of developed countries and generalized forms of infection are rare. We present a case of 67-year-old woman with salmonaella sepsis, deep venous thrombosis, and septic thromboembolism of pulmonary artery complicated with development of necrotizing pneumonia. Generalization of the infectious process was mediated by the presence of polymorphisms in the TLR4 gene. Development of pulmonary infarction is infrequent. Even rarer is a formation of cavities in infarcted lung tissue, usually in the background of the infectious disease. A combination of 2 rare conditions in 1 patient demonstrates the need of multidisciplinary approach in treatment of severe and atypical forms of infectious diseases to evaluate the primary etiology of such state. The article will discuss various aspects of lung tissue damage caused by Salmonella and give a brief overview of the literature on this topic.

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“…Treatment of septic emboli involves underlying infection/source control in combination with antimicrobial therapy [ 1 , 11 ]. Complications of septic emboli include mycotic pulmonary aneurysms treated with coil embolization, vascular obstruction treated with thrombectomy, and abscess/infarct of the lung lobes treated with surgical drainage and/or resection of the infarcted area [ [10] , [11] , [12] , [13] ].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary artery intravascular abscess: A rare complication of incomplete infective endocarditis treatment in the setting of injection drug use

Gupta

Banach

Chirch

2018

IDCases

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Infective endocarditis (IE) is a serious complication of injection drug use. Right-sided IE encompasses 5–10% of all IE cases, with the majority involving the tricuspid valve (TV). The predominant causal organism is Staphylococcus aureus. Most cases of right-sided IE can be successfully treated with antimicrobials, but approximately 5–16% require eventual surgical intervention. We report the case of a 36-year-old female with active injection drug use who developed methicillin-sensitive Staphylococcus aureus IE of the tricuspid valve. Associated with poor adherence to medical therapy as a consequence of opioid addiction, she developed septic emboli to the lungs and an intravascular abscess in the left main pulmonary artery. These long-term potentially fatal, sequelae of incompletely treated IE require surgical intervention, as medical therapy is unlikely to be sufficient. Surgical management may involve TV replacement, pulmonary artery resection, and pneumonectomy. Prevention of these complications may have been achieved by concurrent opioid addiction therapy. An intravascular pulmonary artery abscess is a novel complication of advanced IE that has not been previously reported. This complication likely arose due to incomplete IE treatment as a consequence of opioid addiction, highlighting the need for concurrent addiction management. Intravenous antimicrobial therapy is likely not adequate, and surgical intervention, including pulmonary artery resection and pneumonectomy may be necessary.

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Acute pulmonary embolism leading to cavitation and large pulmonary abscess: A rare complication of pulmonary infarction

Cited by 14 publications

References 4 publications

Simultaneous Giant cavity pulmonary lesion and pneumothorax following COVID-19 pneumonia

Simultaneous Giant cavity pulmonary lesion and pneumothorax following COVID-19 pneumonia

Salmonella sepsis in a patient with TLR4 gene polymorphisms

Pulmonary artery intravascular abscess: A rare complication of incomplete infective endocarditis treatment in the setting of injection drug use

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