Acute Renal Failure Associated with Elevated Plasma Oncotic Pressure

The Use of Hydroxyethyl Starch 200/0,5 as Plasma Subtitutes Is Safe in Hypovolemic Patients as Indicated in Changes of N-Acetyl--Glucosaminidase and Creatinin Serum Parameters

“…When there is an increase in oncotic pressure due to the addition of a colloid, glomerular filtration will be disrupted. It can happen to all compounds that are osmotically active and hard to be filtered (Moran & Kapsner 1987). Therefore, the provision of an amount of crystalloid fluids will prevent urine hyperviscosity from colloidal application (Kumle et al 1999).…”

The Ratio of the Blood Urea Nitrogen/Creatinine Index in Patients with Acute Renal Failure is Decreased due to Dextran or Mannitol

“…Hemodialysis or plasma exchange is recommended to avoid fatal ARF in response to these reagents (2,5,6,8). This report presents 2 cases of ARF; one caused by dextran and another by mannitol.…”

Choice of a Synthetic Colloid for Surgery

“…Severe (life-threatening) anaphylactic reactions with the different kinds of HES preparations may also occur 37 but appear to be rare 36 . Renal dysfunction has been reported with the use of some synthetic colloids (e.g dextrans, HES) 38,39 . The mechanism most likely to cause renal dysfunction is the induction of hyperviscosity by (repeated) infusion of hyperoncotic colloids in dehydrated patients (e.g.…”

“…The mechanism most likely to cause renal dysfunction is the induction of hyperviscosity by (repeated) infusion of hyperoncotic colloids in dehydrated patients (e.g. 10% HES, 10% dextran) 38 . There is no convincing evidence that colloids induce renal problems in the normally hydrated surgical patient 50 .…”