Acute swelling of the limbs: magnetic resonance pictorial review of fascial and muscle signal changes

Revelon, Geraldine; Rahmouni, Alain; Jazaerli, N.; Godeau, Bertrand; Chosidow, Olivier; Authier, Jerome; Mathieu, Didier; Roujeau, Jean‐Claude; Vasile, N

doi:10.1016/s0720-048x(98)00119-3

Cited by 60 publications

(34 citation statements)

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“…MRI plays an important role in the detection of skeletal muscle lesions that change muscle size, shape or signal intensity [5,6]. Review of medical records has shown that MR images can be used to effectively localise muscle lesions in rhabdomyolysis and assess extent [4,[7][8][9][10][11][12].…”

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Skeletal muscle evaluation by MRI in a rabbit model of acute ischaemia

Zhang¹,

Wang²,

Guan³

et al. 2013

BJR

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Objective: To assess rhabdomyolysisassociated skeletal muscle changes induced by complete ischaemia in rabbits using MRI.Methods: Acute ischaemia was induced in the right hind limb of 34 New Zealand white rabbits by arterial ligation. MRI of vastus lateralis was carried out pre-operatively and every hour post-operatively up to 7 h. T 1 weighted images, T 2 weighted images with fat suppression, T 2 maps and diffusion tensor scans were obtained. The correlation of MRI findings with histopathological changes in biopsies of vastus lateralis was examined.Results: Histopathology demonstrated early cellular oedema 1 h post ischaemia and irreversible injuries by 7 h, including loss of striation and broken muscle fibres. T 2 weighted images with fat suppression showed inhomogeneous high signal intensity of vastus lateralis, which progressively increased from 2 h following ischaemia. The T 2 relaxation rate of ischaemic vastus lateralis was significantly greater than normal muscle (p,0.001) and demonstrated a linear increase with time following ischaemia. A similar linear increase was also found in the ischaemic vastus lateralis apparent diffusion coefficient (ADC) 1-5 h post ischaemia (p50.006). Both the T 2 ADC and fractional anisotropy (FA) were significantly higher on the ischaemic side 7 h post ischaemia (for T 2 , p50.02; for ADC, p50.004). Conclusion:Muscle oedema is detectable on MR images and is reflected well by T 2 , ADC and FA values. MRI may have value in clinical evaluation of rhabdomyolysis. Advances in knowledge:Ischaemic changes detected by MRI may have value in the diagnosis of rhabdomyolysis.

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confidence: 99%

Skeletal muscle evaluation by MRI in a rabbit model of acute ischaemia

Zhang¹,

Wang²,

Guan³

et al. 2013

BJR

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“…In DM, increased short tau inversion recovery (STIR) or fat-suppressed, T2-weighted signal intensity can be used to localize muscle inflammation and thereby improve the yield of diagnostic biopsy, as well as aid in the assessment of disease activity and damage (2,3). In addition, anecdotal reports suggest that MRI may also be helpful in noninvasively defining the extent of several inflammatory or edematous cutaneous, subcutaneous, and fascial conditions, including systemic sclerosis, panniculitis, graft-versus-host disease, polyarteritis nodosa, and necrotizing fasciitis (4)(5)(6)(7). Increased subcutaneous T2-weighted MRI signal intensity of unknown clinical significance has been observed in 4 adult DM patients (6).…”

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confidence: 99%

Magnetic resonance imaging detection of occult skin and subcutaneous abnormalities in juvenile dermatomyositis: Implications for diagnosis and therapy

Kimball

Summers

Turner

et al. 2000

Arthritis & Rheumatism

136

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“…MRI is not considered to have a critical role in the diagnosis of rhabdomyolysis due to the non-specific and overlapping image findings with other muscular injuries and myopathy. [16][17][18][19][20][21][22] Likewise, rhabdomyolysis is usually diagnosed on the basis of typical clinical symptoms, history and a laboratory finding of elevated serum CK levels. 1,9 Especially compartment syndrome can be characterized with similar clinical and radiological finding, such as pain, swelling, necrosis and muscular oedema.…”

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confidence: 99%