Adamantinoma of the capitate bone

Diepeveen, W. P.; Hjort, G. H.; Pock-Steen, O. Ch.

doi:10.3109/00016926009171687

Cited by 20 publications

(5 citation statements)

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“…Statistically, the tumor remains unusually prevalent in the tibia, but all other major limb bones have been involved, and involvement of several short bones rarely has been reported [ 28 ]. Other bones that are involved, in order of decreasing frequency, include the humerus [ 29 ], ulna [ 30 ], femur [ 31 ], fibula [ 8 ], radius [ 32 ], innominate bones [ 33 ], ribs [ 34 ], spine[ 35 ] and rarely small bones of the hand and foot [ 36 ]. There have been only six cases of spinal adamantinoma reported [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

Adamantinoma: A clinicopathological review and update

et al. 2008

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Adamantinoma is a primary low-grade, malignant bone tumor that is predominantly located in the mid-portion of the tibia. The etiology of the tumor is still a matter of debate. The initial symptoms of adamantinoma are often indolent and nonspecific and depend on location and extent of the disease. Histologically, classic adamantinoma is a biphasic tumor characterized by epithelial and osteofibrous components that may be intermingled with each other in various proportions and differentiating patterns. To assure the histological diagnosis, pathologists should employ immunohistochemistry for demonstrating the sometimes sparse epithelial cell nests when the radiological features are suggestive of adamantinoma. There is paucity of compiled data over adamantinoma in the literature, hence authors tried to make a comprehensive review which must be of use to beginners and trained pathologists. Our objective is to further define the clinicoradiologic features and pathologic spectra of adamantinoma.

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Section: Introductionmentioning

confidence: 99%

Adamantinoma: A clinicopathological review and update

et al. 2008

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“…The long bones, particularly the tibia (80-85% of cases), are the tumor's primary site [3]. Other bones that are occasionally affected, in decreasing order of frequency, include the humerus, ulna, femur, fibula, radius, innominate bone, rib, spine, and rarely small bones of the hand and foot [11].…”

Section: Discussionmentioning

confidence: 99%

Adamantinoma Metastasis to the Pelvis and Ovaries: A Case Report and Literature Review

Amin,

Azzam,

AlBatati

et al. 2023

Cureus

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Adamantinoma, constituting a minute fraction of primary bone tumors, poses a diagnostic challenge due to its ambiguous histogenesis. This report outlines a distinctive case involving a 27-year-old female with a history of right tibial adamantinoma, presenting with bilateral pulmonary emboli and metastasis to the ovaries and pelvic lymph nodes. Following en bloc resection five years earlier, the patient underwent debulking surgery with hyperthermic intraperitoneal chemotherapy (HIPIC) and intraoperative radiotherapy (IORT) as a palliative measure. The procedure achieved substantial pelvic tumor reduction, and subsequent follow-ups indicated a favorable postoperative trajectory. This case underscores the rarity of adamantinoma metastasis to the ovaries and pelvis, being the first reported instance, shedding light on the challenges and potential benefits of a multimodal palliative approach. Further research is warranted to refine treatment strategies for metastatic adamantinoma and enhance patient outcomes.

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“…There are reports of all other major limb bones having been involved [ 17 ]. Other bones that are involved, in order of decreasing frequency are humerus, ulna, femur, fibula, radius, innominate bone, ribs, spine, and rarely small bones of the hand and foot [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. Rarely, adamantinoma can exclusively arise from the pretibial soft tissues without bony involvement [ 12 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Ewing’s-like Adamantinoma of Tibia Managed by Limb Salvage Surgery Using Long Segment Ilizarov Bone Transport: A Case Report and Review of Literature

Kumar¹,

Pai²,

Rajasubramanya³

2021

JOCR

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Introduction: Adamantinoma is a rare low-grade malignant tumor in young adults. Recent advances in molecular techniques have shown different variants with discordance between genotype and phenotype. This poses a challenge in diagnosis and management. Ewing’s-like adamantinoma is one such variant. The appropriate treatment protocol for this dedifferentiated tumor remains to be established. Here, we present a rare case of Ewing’s-like Adamantinoma treated with limb salvage surgery using three step Ilizarov technique with good results. Case Report: A 38-year-old lady presented at our OPD complaining of recent onset pain and gradual increase in size over a long standing swelling in the right lower tibia. Radiologically was diagnosed as Ewing’s but was not responsive to chemotherapy. A Tru-Cut biopsy showed histological picture of dedifferentiated adamantinoma. Immunohistochemistry showed CD99 positivity. FISH revealed (11;22) translocation confirming Ewing’s-like adamantinoma. She was managed with wide excision followed by staged Ilizarov distraction-osteogenesis and bone transport to correct the 13 cm discrepancy in bone length. There have been no signs of recurrence on post-resection follow-up of 2 years. Patient attained full range of knee and ankle movements. Conclusion: The controversy as to what constitutes the difference between adamantinoma-like Ewing’s and Ewing’s-like adamantinoma persists despite technological advances. The appropriate treatment protocol remains to be established. Ilizarov three step techniques provide a feasible alternative to amputation while circumventing the difficulties of large bone reconstruction in the distal tibia. Keywords: Adamantinoma, Ewing’s-like, Ilizarov, bone transport, dedifferentiated, malignant bone tumor.

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Adamantinoma of the capitate bone

Cited by 20 publications

References 0 publications

Adamantinoma: A clinicopathological review and update

Adamantinoma: A clinicopathological review and update

Adamantinoma Metastasis to the Pelvis and Ovaries: A Case Report and Literature Review

A Rare Case of Ewing’s-like Adamantinoma of Tibia Managed by Limb Salvage Surgery Using Long Segment Ilizarov Bone Transport: A Case Report and Review of Literature

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