Mining-induced seismicity is a reflection of rock geomechanical evolution of geological environment in the natural and man-made systems and in the mining-technical systems. In order to predict and prevent mining-induced seismicity, it is necessary to research geodynamics and stress state of intact rock mass, to determine possible deformations and additional stresses as a result of large-scale rock extraction, conditions of accumulated energy release. For that a geodynamical monitoring is required on every stage of deposit development and a closing. The report considers principal influencing factors of preparation and occurrence of mining-induced earthquakes. Also it estimates precursors and indicators of rock mass breaking point, and experience concerning prediction and prevention of mining-induced seismicity in the Khibiny apatite mines in the Murmansk region, which is the largest mining province.