Abstract. With the improvement of the level of medical information, the major hospitals have the appropriate medical information system (Hospital Information System, HIS) to manage clinical medical data. However, because of the difference of HIS, the structure of clinical medical data is also different, which seriously affects the transmission, compatibility and use of clinical data, that making the data incomplete or can't be effectively used. In this paper, we use the Fast Healthcare Interoperability Resources (FHIR) standard to standardize the exchange of clinical medical data, and build a data sharing platform with multi agent platform, so that the clinical medical data can be integrated by Agent for clinical decisions making.