Abstract-The next generation of navigation and positioning systems must provide greater accuracy and reliability in a range of challenging environments to meet the needs of a variety of mission-critical applications. No single navigation technology is robust enough to meet these requirements on its own, so a multisensor solution is required. Although many new navigation and positioning methods have been developed in recent years, little has been done to bring them together into a robust, reliable, and cost-effective integrated system. To achieve this, four key challenges must be met: complexity, context, ambiguity, and environmental data handling. This paper addresses each of these challenges. It describes the problems, discusses possible approaches, and proposes a program of research and standardization activities to solve them. The discussion is illustrated with results from research into urban GNSS positioning, GNSS shadow matching, environmental feature matching, and context detection.