Adaptive value of PGM polymorphism in laboratory populations of<i>Drosophila melanogaster</i>

Carfagna, M.; Fucci, Laura; Gaudio, Luciano; Pontecorvo, Giovanni; Rubino, Roberta

doi:10.1017/s0016672300019881

Cited by 15 publications

(6 citation statements)

References 32 publications

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“…The fact that this equilibrium applies at 18°C, 25°C and 29°C (Oakeshott, 1979;Carfagna et al, 1980) is also consistent with the geographic homogeneity of Pgm gene frequencies and their lack of consistent association with Tmax, but it contrasts with biochemical evidence indicating differences between the in vitro thermostabilities of respective Pgm allozymes. The thermostabilities of the Pgm12° and Pgm1'°° products appear to be greater than those of Pgm°70, although there are also indications of electrophoretically cryptic thermostability variants within Pgm oo (Trippa et al, 1978b;Fucci et al, 1979).…”

Section: Resultssupporting

confidence: 66%

Latitudinal relationships of esterase-6 and phosphoglucomutase gene frequencies in Drosophila melanogaster

et al. 1981

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SUMMARYGeographic variation in Esterase-6 (Est-6) and Phosphoglucomutase (Pgm) gene frequencies in Australasian populations ot Drosophila melanogaster are compared with analogous data collated from 16 previous reports tor North America and Europe/Asia. A large-scale latitudinal dine is found on all three zoogeographic zones for Est-6 and overall, Est-61°°f requency increases from about 20 per cent around 20° latitude to about 80 per cent approaching 50°l atitude. In contrast, there is no consistent evidence for a latitudinal dine in Pgm gene frequencies in any of the three zones, with Pgm1°° frequency generally about 85 per cent and Pgm 1•20 and Pgm°7° frequencies each between 5 per cent and 10 per cent. The consistent Est-6 dines are attributed to latitudinal selection gradients but no consistent correlations are found between Est-6 gene frequencies and maximum or minimum temperature or rainfall which might be associated with these gradients. The directions of the Est-6 dines in tact run counter to expectations based on the in Vitro thermostabilities of the respective allozymes.

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Section: Resultssupporting

confidence: 66%

Latitudinal relationships of esterase-6 and phosphoglucomutase gene frequencies in Drosophila melanogaster

et al. 1981

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“…Two patterns of results often obtained are the rapid elimination of the inversions from the populations and the restabilisation of the enzyme allele frequencies around values characteristic of the original wild-caught populations (e.g., Lewontin, 1958;Inoue, 1979;Carfagna et a!., 1980;PalabostCharles, 1982). Moreover, essentially the same results are often obtained in all the environments tested, despite the imposition of some relatively severe stresses, including , in relation to the enzymes, regimes which should impinge directly on the functions of the specific enzymes tested (e.g., extremes of substrate concentration; Zera et aL, 1983 for a review).…”

Section: Introductionmentioning

confidence: 99%

Chromosome inversion polymorphisms inDrosophila melanogaster IV. Inversion and Adh allele frequency changes under selection for different development times

1987

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Replicate lines from two wild-caught populations of D. melanogaster were selected for fast, intermediate or slow development times. After 36 generations of selection, the average time to the first emergence of adults was about half a day less in lines selected for fast development than it was in the other lines. Polymorphisms for Adh and six chromosome inversions were monitored during the course of selection. Average Adh F allele frequencies become higher over the 36 generations in lines selected for fast development than in other lines. Collating this result with earlier reports, an association with development time has now been found for three enzyme polymorphisms in laboratory D. melanogaster populations selected for rapid development. Allele frequencies at all three loci show latitudinal dines in natural populations, as does development time, and for each of the three polymorphisms the allele associated with rapid development in the laboratory selection lines is also associated with rapid development in the latitudinal dines. This suggests that development time selection may contribute to the latitudinal dines for the enzyme polmorphisms. The frequencies of four inversions showing latitudinal dines generally decreased during the experiment, while two inversions not showing latitudinal dines generally persisted or increased in frequency. Only one inversion, In(3R)Mo, showed clear differences in response among different development time regimes and this inversion does not show a latitudinal dine. There was thus no evidence that geographic patterns in inversion frequencies are the result of development time selection.

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“…Adaptive differences have been found for a regulatory gene that controls PGM1 expression in the liver of rainbow trout, with faster developmental rates found for individuals that possess increased expression of PGM1 (Allendorf et al 1983). PGM polymorphisms in Drosophila melanogaster may be subject to balancing selection (Carfagna et al 1980;Oakshott et al 1985) and subsequent work has shown this gene to be evolving in an adaptive manner (Verrelli and Eanes 2000).…”

Section: Discussionmentioning

confidence: 96%

Analysis of F ST outliers at allozyme loci in Pacific salmon: implications for natural selection

Aguilar

2006

Environ Biol Fish

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Natural selection has been invoked to explain the observed geographic distribution of allozyme allele frequencies for a number of teleost species. The effects of selection on allozyme loci in three species of Pacific salmon were tested. A simulation-based approach to estimate the null distribution of population differentiation (F ST ) and test for F ST outliers was used. This approach showed that a majority of allozyme loci conform to neutral expectations predicted by the simulation model, with relatively few F ST outliers found. No consistent F ST outlier loci were found across species. Analysis of population sub-groups based on geography and genetic identity reduced the number of outlier loci for some species, indicating that large geographic groups may include genetically divergent populations and/or that there is geographic heterogeneity in selection pressure upon allozyme loci. Two outlier allozyme loci found in this analysis, lactate dehydrogenase-B and malic enzyme, have been shown to be influenced by selection in other teleost species. This approach is also useful in identifying allozyme loci (or other genetic markers) that meet assumptions for population genetic study.

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Adaptive value of PGM polymorphism in laboratory populations ofDrosophila melanogaster

Cited by 15 publications

References 32 publications

Latitudinal relationships of esterase-6 and phosphoglucomutase gene frequencies in Drosophila melanogaster

Latitudinal relationships of esterase-6 and phosphoglucomutase gene frequencies in Drosophila melanogaster

Chromosome inversion polymorphisms inDrosophila melanogaster IV. Inversion and Adh allele frequency changes under selection for different development times

Analysis of F ST outliers at allozyme loci in Pacific salmon: implications for natural selection

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