Addiction and Liver Disease

Ali, Akmat; Yeasmin, F; Nag, MN

doi:10.3329/medtoday.v25i2.17926

Cited by 2 publications

(2 citation statements)

References 66 publications

(60 reference statements)

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“…Alcohol consumption is one of the leading risk factors for the burden of disease globally and has greatly reduced the level of public health in the world [1]. According to the World Health Organization, the annual global average alcohol consumption is 8 L per person aged 15 years and over in the United States, while the European countries consume the most alcohol in the world (11.3 L per person) [2]. In Iran, the production and consumption of alcoholic beverages are prohibited, so they are produced or consumed secretly; thus, it is too difficult to measure the exact amount of the alcohol consumed.…”

Section: Introductionmentioning

confidence: 99%

Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data

et al. 2022

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Objectives Opium use, cigarette smoking, and alcohol consumption are serious health problems in many countries including Iran. The present study aimed to examine the association between the opium use, cigarette smoking and alcohol consumption with liver enzyme levels in Southern Iran. This analytical cross-sectional study was conducted in 2020. The entire population of the Fasa Persian cohort study in the southern region of Iran was selected as the sample. Accordingly, 10,145 people participated in the study. Results Results indicated that there was a significant relationship between cigarette smoking and alcohol consumption with liver enzymes (AST, ALT, and ALP). There was also a significant relationship between inhaled opium and liver enzymes, but oral opium revealed no significant relationship with the activity of liver enzymes. Accordingly, policymakers of the health care system are recommended to hold educational programs to improve the health literacy level of the society and take effective preventative strategies in reducing the use of these substances.

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Section: Introductionmentioning

confidence: 99%

Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data

et al. 2022

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“…It is well known that the addiction to heroin is related to a lot of short-term and long-term effects on the health of drug abusers. The main part of the long-term effects are related with the use of contaminated heroin, infected needles, syringes, spoons (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17). The heroin addicted subjects are the main risk group for infection with hepatitis C virus (HCV).…”

Section: Introductionmentioning

confidence: 99%

HCV AND DRUG ABUSERS – morphological changes (Liver biopsy in CHC and heroin abuse)

Lubomirova¹,

Marinova²,

Ivanova³

et al. 2018

MedInform

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The aim of the study was to evaluate the morphological changes in the liver biopsies from patients with chronic hepatitis C (CHC) and heroin abuse (HA). Material and methods: In the study were included 10 patients with CHC and HA (9 m, 1 f, mean age 24,2±3,26 y) and 36 patients (25 m, 9 f) with no HA and CHC (n=22, mean age 32,68 ±11,41y) or chronic hepatitis B (CHB, n=14, mean age 24,00±3,66 y). The diagnosis of chronic hepatitis was put according to standard criteria and liver biopsy was done in all cases. The grading of activity and staging of fibrosis by METAVIR, the presence of steatosis and depletion of glycogen content was evaluated after using HE, V. Gieson, Gomori and PAS stains. Results: In the group of HA patients with CHC were found more often moderate grade of inflammation (A2, 60%) and clinically significant stage of fibrosis (F2, 70%) while in the both groups of non-HA patients with CHC or CHB the prevalences of mild grade of activity (A1, 59% and 50%, respectively) and early stage of fibrosis (F1, 59% and 71%) were predominant. No significant differences were found in the comparison of HA patients with CHC and non-HA control groups regarding the presence of steatosis and decrease of glycogen contents in hepatocytes. In conclusion, our study showed that in liver biopsies of patients with CHC and heroin abuse there were more severe morphological changes including grading and staging of chronic hepatitis compared to the cases with CHC or CHB without history of drug abuse.

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Addiction and Liver Disease

Abstract: Abstract

Cited by 2 publications

References 66 publications

Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data

Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data

HCV AND DRUG ABUSERS – morphological changes (Liver biopsy in CHC and heroin abuse)

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