Additional Targeted Biopsy in Clinically Suspected Prostate Cancer: Prospective Randomized Comparison between Contrast-Enhanced Ultrasound and Sonoelastography Guidance

Koh, Jieun; Jung, Dae Chul; Oh, Young-Jin; Yoo, Moon Gyu; Noh, Songmi; Han, Kyunghwa; Rha, Koon Ho; Choi, Young Deuk; Hong, Sung Joon

doi:10.1016/j.ultrasmedbio.2015.06.024

Cited by 15 publications

(11 citation statements)

References 18 publications

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“…Several studies have shown that CEUS can improve the ability of ultrasound to detect and characterize PCa [7,8] and thus might improve cancer detection by biopsy as well as reduce the number of biopsy cores needed for diagnosis confirmation [9]. Recent studies have shown an improved PCa detection rate when CEUS is applied for US-guided prostate biopsy in comparison to systematic biopsies without CEUS [10,11]. One of the first contrast agents used for prostate ultrasound was sulfur hexafluoride (Sono-Vue ® , Bracco, Milan), enabling real-time low mechanical index (MI) CEUS [12].…”

Section: Introductionmentioning

confidence: 99%

Contrast-Enhanced Ultrasound (CEUS) and Quantitative Perfusion Analysis in Patients with Suspicion for Prostate Cancer

et al. 2018

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Section: Introductionmentioning

confidence: 99%

Contrast-Enhanced Ultrasound (CEUS) and Quantitative Perfusion Analysis in Patients with Suspicion for Prostate Cancer

et al. 2018

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“…Koh et al compared CEUS guided biopsy and sonoelastography guided biopsy. Despite the small cohort, the authors concluded that elastography may improve systematic biopsy results [14].…”

Section: Multiparametric Ultrasonographymentioning

confidence: 99%

Elastography in prostate gland imaging and prostate cancer detection

Tyloch

Adamowicz

et al. 2018

Med Ultrason

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Transrectal prostate biopsies under ultrasonography guidance remain the gold standard for the detection of prostate cancer (PCa). Transrectal ultrasonography (TRUS), however, has a limited sensitivity in PCa detection. Prostate elastography (TRES) increases the sensitivity of a TRUS examination. Therefore, the aim of this review is to discuss the usefulness of TRES in prostate gland imaging for the diagnosis and management of prostate cancer based on published literature. The advantages of transrectal elastography were analysed in the context of better diagnostic performance provided by this method. TRES provides additional information for the detection and biopsy guidance concerning prostate cancer, enabling a significant reduction in the number of biopsies.

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“…Tumor angiogenesis in PCA produces increased microvascular density which can be measured by CEUS. Suspicious areas in the prostate are asymmetric and have rapid or relatively increased contrast enhancement [46].…”

Section: Contrast-enhanced Ultrasoundmentioning

confidence: 99%

“…Li et al performed a large meta-analysis of 16 studies including 2624 patients assessing CEUS in PCA and found a pooled sensitivity and specificity of 70% and 74% [47]. However, one study found no significant difference in PCA detection rate based on core number between CEUS targeted-biopsy (18.8%) and SBx (18.3%) in a relatively small population of 26 patients [46]. In contrast, a recent large prospective study with 1024 patients found CEUS targeted-biopsy improved detection of clinically significant PCA compared to Sbx (28.7% vs 25.3% p = 0.000) [45].…”

Section: Contrast-enhanced Ultrasoundmentioning

confidence: 99%

Prostate Cancer Detection and Diagnosis: Role of Ultrasound with MRI Correlates

2019

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Purpose of Review Prostate cancer (PCA) detection and diagnosis has rapidly changed in recent years, with medical imaging playing an instrumental component. Multiparametric magnetic resonance imaging (MRI) has led to an alternative diagnostic pathway for patient triage and diagnosis. Ultrasound (US) is already essential to this pathway, and development of new US technologies ensures it will assume an even more important role. Recent Findings Conventional US is widely used for anatomic guidance during prostate biopsy, but has low PCA detection rates. Ultrasound elastography and contrastenhanced US are promising for improving PCA detection, have been utilized in addition to traditional systemic biopsy, and provide complementary information to MRI. Summary Here we summarize the current clinical use and newest developments in prostate US. We also present their MRI correlates with the vision that the two modalities will be used closely together in the future to improve PCA care. Keywords Prostate cancer Á Ultrasound Á Ultrasound elastography Á MRI Á Detection Á Diagnosis This article is part of the Topical Collection on Ultrasound.

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Additional Targeted Biopsy in Clinically Suspected Prostate Cancer: Prospective Randomized Comparison between Contrast-Enhanced Ultrasound and Sonoelastography Guidance

Cited by 15 publications

References 18 publications

Contrast-Enhanced Ultrasound (CEUS) and Quantitative Perfusion Analysis in Patients with Suspicion for Prostate Cancer

Contrast-Enhanced Ultrasound (CEUS) and Quantitative Perfusion Analysis in Patients with Suspicion for Prostate Cancer

Elastography in prostate gland imaging and prostate cancer detection

Prostate Cancer Detection and Diagnosis: Role of Ultrasound with MRI Correlates

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