Additive manufacturing in biomedical field: a critical review on fabrication method, materials used, applications, challenges, and future prospects

Wazeer, Adil; Das, Apurba; Sinha, Arijit; SU, Ziyi; Karmakar, Amit

doi:10.1007/s40964-022-00362-y

Cited by 18 publications

(3 citation statements)

References 188 publications

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“…FDM has risen in popularity among additive manufacturing techniques because of its accessibility and material adaptability. This technique has been used over the years to generate a variety of materials for application in the aerospace [52], medical [53], and automotive industries, including plastics, powder, ceramics, and composites [54]. This procedure involves layering a partially built object with semisolid filament material that has been extruded through a heated nozzle.…”

Section: Fabrication and Testingmentioning

confidence: 99%

A Decision-Making Carbon Reinforced Material Selection Model for Composite Polymers in Pipeline Applications

Mustafa

Raja²,

Alasadi

et al. 2023

Advances in Polymer Technology

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Pipes are manufactured primarily through the extrusion process. One of the material extrusion processes in recent digital manufacturing is additive manufacturing’s fusion deposition modeling. Pipes are made from various materials such as metal and plastic/polymers, and the main challenge has been in selecting the pipe material for the customized application. For the creation of water-passing tubes, this research has chosen appropriate carbon-reinforced polymers that can be used with filament made of polyether ether ketone (PEEK) and polyethylene terephthalate glycol (PETG). For this goal, the analytical hierarchy process, also known as the AHP, is used to choose the best material based on factors such as cost, temperature resistance, printing speed, and mechanical properties of the material. The results revealed that PEEK-CF is a better material for the customized impeller application than PETG-CF. The PEEK-CF obtains the higher priority value of 0.6363, and the PETG-CF obtains 0.2791. This decision-making technique can be used to select other comparable customized applications.

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Section: Fabrication and Testingmentioning

confidence: 99%

A Decision-Making Carbon Reinforced Material Selection Model for Composite Polymers in Pipeline Applications

Mustafa

Raja²,

Alasadi

et al. 2023

Advances in Polymer Technology

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“…However, AM processing in medical applications can cause damage to mechanical properties, resulting in undesirable transformations and distortion 4 . In dentistry, additive manufacturing offers a variety of material options like polymers, ceramics, and alloys, and can be used to produce splints, orthodontic appliances, and surgical guides 5 .…”

Section: Introductionmentioning

confidence: 99%

Effects of washing agents on the mechanical and biocompatibility properties of water-washable 3D printing crown and bridge resin

Liu,

Jin,

Lim

et al. 2024

Sci Rep

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Three-dimensional (3D) printing, otherwise known as additive manufacturing in a non-technical context, is becoming increasingly popular in the field of dentistry. As an essential step in the 3D printing process, postwashing with organic solvents can damage the printed resin polymer and possibly pose a risk to human health. The development of water-washable dental resins means that water can be used as a washing agent. However, the effects of washing agents and washing times on the mechanical and biocompatibility properties of water-washable resins remain unclear. This study investigated the impact of different washing agents (water, detergent, and alcohol) and washing time points (5, 10, 20, and 30 min) on the flexural strength, Vickers hardness, surface characterization, degree of conversion, biocompatibility, and monomer elution of 3D printed samples. Using water for long-term washing better preserved the mechanical properties, caused a smooth surface, and improved the degree of conversion, with 20 min of washing with water achieving the same biological performance as organic solvents. Water is an applicable agent option for washing the 3D printing water-washable temporary crown and bridge resin in the postwashing process. This advancement facilitates the development of other water-washable intraoral resins and the optimization of clinical standard washing guidelines.

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“…Therefore, to give a base for large-scale production, it is essential to identify or develop new cost-effective biocompatible and sterilizable materials [80] that are able to assure accuracy, precision and high quality during device development and after postprocessing/finishing procedures [81][82][83]. However, research and development studies in the medical sector [84,85] must be addressed to meet all of the governance requirements [86].…”

Section: Introductionmentioning

confidence: 99%

The Upper Limb Orthosis in the Rehabilitation of Stroke Patients: The Role of 3D Printing

Demeco,

Foresti,

Frizziero

et al. 2023

Bioengineering

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Stroke represents the third cause of long-term disability in the world. About 80% of stroke patients have an impairment of bio-motor functions and over half fail to regain arm functionality, resulting in motor movement control disorder with serious loss in terms of social independence. Therefore, rehabilitation plays a key role in the reduction of patient disabilities, and 3D printing (3DP) has showed interesting improvements in related fields, thanks to the possibility to produce customized, eco-sustainable and cost-effective orthoses. This study investigated the clinical use of 3DP orthosis in rehabilitation compared to the traditional ones, focusing on the correlation between 3DP technology, therapy and outcomes. We screened 138 articles from PubMed, Scopus and Web of Science, selecting the 10 articles fulfilling the inclusion criteria, which were subsequently examined for the systematic review. The results showed that 3DP provides substantial advantages in terms of upper limb orthosis designed on the patient’s needs. Moreover, seven research activities used biodegradable/recyclable materials, underlining the great potential of validated 3DP solutions in a clinical rehabilitation setting. The aim of this study was to highlight how 3DP could overcome the limitations of standard medical devices in order to support clinicians, bioengineers and innovation managers during the implementation of Healthcare 4.0.

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Additive manufacturing in biomedical field: a critical review on fabrication method, materials used, applications, challenges, and future prospects

Cited by 18 publications

References 188 publications

A Decision-Making Carbon Reinforced Material Selection Model for Composite Polymers in Pipeline Applications

A Decision-Making Carbon Reinforced Material Selection Model for Composite Polymers in Pipeline Applications

Effects of washing agents on the mechanical and biocompatibility properties of water-washable 3D printing crown and bridge resin

The Upper Limb Orthosis in the Rehabilitation of Stroke Patients: The Role of 3D Printing

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