Adenocarcinoma arising in an ectopic mediastinal pancreas

Ectopic pancreas in a giant mediastinal cyst

“…Following radical resection, prognosis is favorable. In the reported cases, no signs of recurrence were found during follow‐up (up to 8 years), except for a single case with pancreatic adenocarcinoma arising in the ectopic pancreas, with sternal metastases 6 months after primary resection .…”

“…Alternatively, isolated ectopic pancreas without anatomical or vascular connections to the normal pancreas is extremely rare. To the best of our knowledge, only 20 cases have been reported previously since the first description of this entity in the literature by Shillitoe and Wilson . Clinical presentation is variable, with atypical chest pain and dyspnea most frequently reported.…”

“…These lesions are almost exclusively found in the anterior part of the mediastinum, are mostly cystic in nature and are generally benign. However, adenocarcinoma arising from a mediastinal ectopic pancreas has been reported . Differential diagnoses of anterior mediastinal cystic lesions include thymic cyst, cystic teratoma, lymphangioma, pericardial and bronchogenic cyst .…”

“…Regarding surgical approach, most of the documented cases have been operated through a median sternotomy, although resection through thoracotomy has also been reported. Especially in cases with large cysts, dense adhesions can often be found with involvement of adjacent mediastinal structures , sometimes necessitating additional surgical resection. Following radical resection, prognosis is favorable.…”

Therapeutic Management of Submucosal Gastric Tumors: A Series of Six Cases with Ectopic Pancreas in the Stomach and Description of a Novel Endoscopic Full-Thickness Resection Technique of the Gastric Wall

“…The highest incidence of ectopic pancreas occurs in the 4 th , 5 th and 6 th decade, 2-3 times more frequently in males [4,5]. The condition is usually asymptomatic and may become clinically evident when complicated by pancreatitis [6], malignancy [7,8], obstruction [9], ulceration and bleeding [10,11]. Pre-interventional diagnosis of submucosal tumors, especially of heterotopic pancreas is considered difficult, even in experienced hands.…”