Adenoid Cystic Carcinoma of Buccal Mucosa: A Rare Case Report

Abstract

Adenoid cystic carcinoma is a malignant neoplasm most commonly originating in salivary glands of head and neck region. Among intra oral adenoid cystic carcinoma, buccal mucosa is among the rarest sites. We report a case of adenoid cystic of buccal mucosa in a 40-year old female. We have discussed the clinical features, histopathology, diagnosis and treatment along with a brief review of the relevant literature. Although the buccal mucosa is an uncommon site for adenoid cystic carcinoma, the relatively indolent growth pattern of this case and its location which is rather atypical for this type of salivary gland malignancy primarily warrants the necessity behind reporting of this case. Secondly, adenoid cystic carcinoma should be considered in the differential diagnosis of mass of buccal mucosa. It is important to identify such cases rather early and surgical removal with adequate margins is the treatment of choice.

Adenoid cystic carcinoma of the vagina

“…Among intraoral ACC, the buccal mucosa was among the rarest sites. [14] In the present case, ACC of the vagina is also very rare. Literatures were searched, but a similar case report could not be found.…”

Adenoid Cystic Carcinoma of Buccal Mucosa: A Rare Presentation

“…Malignant neoplasms of the salivary glands in the head and neck are relatively rare, accounting for only less than 7% of all neoplasms, of which about 10% are Adenoid Cystic Carcinomas [1,2]. ACC was first described by Theodor Bilroth in 1856, as cylindromas, in his histological studies where he described it as long amorphous compartments called "cylinders".…”

“…ACC was first described by Theodor Bilroth in 1856, as cylindromas, in his histological studies where he described it as long amorphous compartments called "cylinders". It is only recently that the tumor has been renamed as adenoid cystic carcinoma (ACC) (Kaiser) [1]. ACCs are mostly reported in the minor salivary glands, and less frequently in the major salivary glands.…”

“…Salivary gland neoplasms comprise a diverse group of tumors with varied histological characteristics and clinical behavior patterns. Salivary gland neoplasms show infiltrative behavior and late loco-regional recurrence and distant metastasis, these mandate a proper diagnosis and treatment [1].…”

Adenoid Cystic Carcinoma of Tongue: A Case Report & Review of Literature

“…Salivary gland neoplasms constitute a diverse group of tumors, exhibiting different histological characteristics and variable clinical behavior pattern 7 . Although almost 40 histological types of SGTs exist, some are exceedingly rare 8 .Histopathologically, AdCC is identified as a tumor with biphasic differentiation of epithelial and myoepithelial cell (MEC), which often shows mixed patterns of cribriform, tubular and solid types 9 .…”