Adenoidal Hypertrophy and Allergic Rhinitis: Is There an Inverse Relationship?

Ameli, Franco; Brocchetti, Fabio; Tosca, Maria Angela; Signori, Alessio; Ciprandi, Giorgio

doi:10.2500/ajra.2013.27.3854

Cited by 52 publications

(54 citation statements)

References 56 publications

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“…In the larynx, a correlation between increased endolaryngeal mucous with positive atopic skin prick testing has been reported as well as an increase in endolaryngeal mucous in two patients exposed to transoral allergen stimulation . There has been little published on nasopharyngeal findings in atopic disease other than in regard to the adenoid pad, as mentioned above . One study demonstrated increased interleukin 4 (IL‐4), number of eosinophils, and decreased neutrophils in biopsies taken of the torus tubarius in atopic patients .…”

Section: Discussionmentioning

confidence: 99%

“…10 A study comparing skin prick testing to endoscopic findings did not correlate this association, 12 and another study demonstrated poor reliability of endoscopy for findings of mucosal inflammation. 13 In pediatric patients, endoscopic nasal findings predictive of allergic rhinitis included inferior turbinate and middle turbinate contact, whereas turbinate color was not predictive of allergic rhinitis, 14,15 and an inverse relationship between adenoid hypertrophy and allergic disease has been demonstrated in the pediatric population. 12,15 Several studies have demonstrated the elevated prevalence of allergic rhinitis in patients with chronic rhinosinusitis.…”

Section: Discussionmentioning

confidence: 99%

“…13 In pediatric patients, endoscopic nasal findings predictive of allergic rhinitis included inferior turbinate and middle turbinate contact, whereas turbinate color was not predictive of allergic rhinitis, 14,15 and an inverse relationship between adenoid hypertrophy and allergic disease has been demonstrated in the pediatric population. 12,15 Several studies have demonstrated the elevated prevalence of allergic rhinitis in patients with chronic rhinosinusitis. One study out of Korea demonstrated a Fig.…”

Section: Discussionmentioning

confidence: 99%

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Predictive findings of allergic disease in fiberoptic nasolaryngoscopy

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Predictive findings of allergic disease in fiberoptic nasolaryngoscopy

et al. 2014

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“…The cost of associated loss of productivity is estimated at between $2–3 billion [5, 6]. Apart from being a ‘nuisance disease’ leading to a significant decrease quality of life [7], AR can be comorbid with other respiratory and non-respiratory disorders such as asthma [8], chronic otitis media [9], rhinosinusitis [10], turbinate hypertrophy [11], secondary obstructive sleep apnea, and sleep difficulties [12]. Evidence suggests that AR often occurs co-morbidly with mood disorders, such as depression [13], and suicidal behaviors [14].…”

Section: Introductionmentioning

confidence: 99%

Mental Health in Allergic Rhinitis: Depression and Suicidal Behavior

Amritwar

Lowry

Brenner³

et al. 2017

Curr Treat Options Allergy

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Opinion Statement A high proportion of suicides visit their medical provider in the month prior to death, but depression, suicidal thoughts, and substance use are seldom addressed. For the clinicians routinely treating a substantial patient population with allergic diseases, there are additional concerns, as allergy has been linked with both depression and suicidal behavior. While psychotropic medications may affect diagnosis of allergies, medications used to treat allergies impact mood and behavior. Thus, we present an overview of the overlap of allergic rhinitis with depression and suicidal behavior in adults, based on clinical and epidemiological data, and our research and clinical experience. In summary, we suggest: 1) inquiring among patients with allergies about personal and family history of depression, substance use disorders, suicidal ideation and attempts 2) increased mindfulness regarding the potential effects of allergy medications on mood and behavior; and 3) for people identified with certain types of depression or increased suicide risk, a systematic multilevel collaborative approach. While for practical reasons the majority of patients with depression will continue to be treated by general or family practitioners, the allergy-treating provider should always consider integrated care for bipolar, psychotic or suicidal depression and incomplete remission, or relapsing and highly recurrent course. While awaiting results of much needed basic and clinical research to guide clinical approach for patients with comorbid allergic rhinitis and depression, the simple steps recommended here are expected to improved clinical outcomes in depression, including, on a large scale, reduced premature deaths by suicide.

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“…The complete description of the procedure was previously described in detail (7). Briefly, the nasal fossa was evaluated in 3 steps that allowed to investigate the following anatomical structures according to Lang's description (8): i) the inferior turbinate and its relationship with the inferior meatus, the inferior part of the septum, the aspect of the mucosa and the presence of secretion, and the rhinopharynx; ii) the maxillary line (which begins superiorly at the middle turbinate attachment corresponding at the aggernasi area), the olfactory tract when possible, the middle turbinate and its contacts with septum or uncinate process; iii) the uncinate process, the middle meatus and the half posterior of the nasal septum, the ethmoidalis bulla and its mucosal contacts, and the spheno-ethmoidal recess; this step was possible only when the space inside the nasal fossa was adequate, otherwise after local decongestion.…”

Section: Study Proceduresmentioning

confidence: 99%

Salso-Sulphide Thermal Water in the Prevention of Recurrent Respiratory Infections in Children

Varricchio¹,

Giuliano²,

Capasso³

et al. 2013

Int J Immunopathol Pharmacol

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Recurrent respiratory infections (RRI) represent a social problem for both the pharmaco-economic impact and the burden on the family. Thermal water is popularly well accepted. However, there is no scientific evidence of its preventive activity on recurrent respiratory tract infections (RRI). Therefore, the purpose of this study was to evaluate the effects of Agnano thermal water nasal irrigation on RRI prevention in children. A total of 107 children (70 males, mean age 4.5±1.2 years) with RRI were enrolled in the study. At baseline, children were randomly assigned to the treatment with: A) inhaled crenotherapy with salso-sulphide water or B) isotonic saline (NaCl 0.9%). Inhaled therapy was performed using nasal washing by Rino-jet (ASEMA srl, Milan, Italy) b.i.d. for 12 days. Nasal washing lasted 2 minutes per nostril. Immediately before washing, children inhaled 1 l of water by stream inhalation per 2 minutes. Crenotherapy was capable of significantly reducing: the number of respiratory infections, nasal symptoms, neutrophil and bacteria count, turbinate and adenoidal hypertrophy, presence of biofilm, and blockage of ostiomeatal complex (OCM). In conclusion, this study provides the first evidence that Agnano crenotherapy may be capable of preventing RRI in children as it exerts some positive effects, such as reduction of nasal obstruction, OCM blockage, biofilm, and inflammatory events.

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Adenoidal Hypertrophy and Allergic Rhinitis: Is There an Inverse Relationship?

Abstract: This real-life study shows that large adenoids may be associated with absence of allergy, whereas large turbinates may be associated with small adenoids.

Cited by 52 publications

References 56 publications

Predictive findings of allergic disease in fiberoptic nasolaryngoscopy

Predictive findings of allergic disease in fiberoptic nasolaryngoscopy

Mental Health in Allergic Rhinitis: Depression and Suicidal Behavior

Salso-Sulphide Thermal Water in the Prevention of Recurrent Respiratory Infections in Children

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