Adenomatoid tumor of adrenal gland. Case report and review of the literature

Füredi, Gábor; Szilágyi, Anna; Bencsik, Zsuzsa; Altorjay, Áron

doi:10.1556/oh.2007.28113

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Depending on the anatomic site its name differs: pleura (lining the lungs and chest wall), peritoneum (lining the abdominal organs and wall), pericardium (lining the heart) and tunica vaginalis (lining the testes). Adenomatoid tumors usually occur in the genital tract of both sexes and less frequently in heart, 2 mediastinum, 3‐5 pancreas, 6 liver, 7‐12 pleura, 13 mesocolon, 14 omentum, 14‐16 lymph node, 17 peritoneum, 9,18 intestinal mesentery, 19 adrenal glands, 20‐55 and skin 56 . Most tumors are discovered incidentally.…”

Section: Discussionmentioning

confidence: 99%

Adenomatoid tumor of the skin: Differential diagnosis of an umbilical erythematous plaque

et al. 2020

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Adenomatoid tumors are benign tumors of mesothelial origin that are usually encountered in the genital tract. Although they have been observed in other organs, the skin appears to be a very rare location, with only one case reported in the literature to our knowledge. We report a second case of an adenomatoid tumor, arising in the umbilicus of a 44-year-old woman. The patient presented with an 8-month-old erythematous and firm plaque under the umbilicus. A skin biopsy showed numerous microcystic spaces dissecting a fibrous stroma and lined by flattened to cuboidal cells with focal intraluminal papillary formation. This little-known diagnosis constitutes a diagnostic pitfall for dermatopathologists and dermatologists, and could be misdiagnosed as other benign or malignant entities. Through this case report, a practical approach and diagnostic keys have been devised to avoid misdiagnosis and overtreatment.

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Section: Discussionmentioning

confidence: 99%

Adenomatoid tumor of the skin: Differential diagnosis of an umbilical erythematous plaque

et al. 2020

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Adenomatoid Tumor of the Adrenal Gland: Differential Diagnosis Using Immunohistochemistry

Burel‐Vandenbos

Cardot‐Leccia

Haudebourg

et al. 2009

Methods of Cancer Diagnosis, Therapy, and Prognosis

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Cystic Lymphangioma-like Adenomatoid Tumor of the Adrenal Gland: Case Presentation and Review of the Literature

Bisceglia¹,

Carosi²,

Scillitani

et al. 2009

Advances in Anatomic Pathology

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Adenomatoid tumors (AT) are usually found in the genital tract of both sexes. They are very rarely located in extragenital sites, and are exceedingly rare in the adrenal. AT of the adrenal gland (AT-AG) are nonfunctioning, usually discovered incidentally and confused on imaging with other more common adrenal neoplasms. The overwhelming majority occur in males. Thirty-four cases have been reported so far, more often presenting grossly as solid tumors, rarely as solid with cystic areas, and 5 cases were almost entirely cystic. At histology they can be either circumscribed or locally infiltrative, and may pose diagnostic difficulties when the pathologist relies on morphology alone or is challenged on frozen section. On light microscopy the diagnosis may be very difficult if the tumor is rich in vacuolated cells, mimicking metastatic signet ring-cell adenocarcinoma. Immunophenotyping and/or electron microscopy are paramount in helping to ascertain their mesothelial lineage. Lymphangioma is the main histologic mimic of solid-cystic and cystic AT-AG, but lymphangioma is immunopositive for endothelial markers and negative for cytokeratins and mesothelial markers. Ultrastructural analysis has been performed in 10 published cases of AT-AG, in all of which the classical microvilli of coelomic type were always observed. In brief we report herein the sixth case of cystic lymphangioma-like AT, which was incidentally discovered during clinical follow-up in a 39-year-old man undergoing cancer staging and surveillance after surgery. The adrenal tumor was 5.5 cm in size and was fully investigated immunohistochemically and ultrastructurally. A complete review of the literature is also presented.

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Adenomatoid tumor of adrenal gland. Case report and review of the literature

Cited by 3 publications

References 9 publications

Adenomatoid tumor of the skin: Differential diagnosis of an umbilical erythematous plaque

Adenomatoid tumor of the skin: Differential diagnosis of an umbilical erythematous plaque

Adenomatoid Tumor of the Adrenal Gland: Differential Diagnosis Using Immunohistochemistry

Cystic Lymphangioma-like Adenomatoid Tumor of the Adrenal Gland: Case Presentation and Review of the Literature

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