Adenomyomatosis of the Gallbladder: Another Cause for a “Hot” Gallbladder on <sup>18</sup>F-FDG PET

Maldjian, Pierre D.; Ghesani, Nasrin; Ahmed, Shahida; Liu, Yiyan

doi:10.2214/ajr.05.1284

Cited by 51 publications

(23 citation statements)

References 7 publications

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“…There have been reports of increased uptake of fluorine-18 fluorodeoxyglucose (FDG) within areas of adenomyomatosis at PET, a potential source of false-positive results when characterizing gallbladder lesions(28). Inflammatory Polyps.-Inflammatory polyps represent 10% of all gallbladder polyps in surgi-…”

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confidence: 99%

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Mellnick¹,

Menias

Sandrasegaran³

et al. 2015

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Gallbladder polyps are seen on as many as 7% of gallbladder ultrasonographic images. The differential diagnosis for a polypoid gallbladder mass is wide and includes pseudotumors, as well as benign and malignant tumors. Tumefactive sludge may be mistaken for a gallbladder polyp. Pseudotumors include cholesterol polyps, adenomyomatosis, and inflammatory polyps, and they occur in that order of frequency. The most common benign and malignant tumors are adenomas and primary adenocarcinoma, respectively. Polyp size, shape, and other ancillary imaging findings, such as a wide base, wall thickening, and coexistent gallstones, are pertinent items to report when gallbladder polyps are discovered. These findings, as well as patient age and risk factors for gallbladder cancer, guide clinical decision making. Symptomatic polyps without other cause for symptoms, an age over 50 years, and the presence of gallstones are generally considered indications for cholecystectomy. Incidentally noted pedunculated polyps smaller than 5 mm generally do not require follow-up. Polyps that are 6-10 mm require follow-up, although neither the frequency nor the length of follow-up has been established. Polyps that are larger than 10 mm are typically excised, although lower size thresholds for cholecystectomy may be considered for patients with increased risk for gallbladder carcinoma, such as patients with primary sclerosing cholangitis.

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Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Mellnick¹,

Menias

Sandrasegaran³

et al. 2015

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“…Limitations of the method are chronic inflammatory conditions related to adenomyomatosis with increased glucose metabolism which can lead to falsepositive FDG PET findings. 13 In these cases FDG PET is recommended after reduction of the serum level of C-reactive protein. 14 According to treatment algorithm developed by Pellino et al symptomatic patients with GBA should undergo surgery.…”

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confidence: 99%

Segmental type of gallbladder adenomyomatosis – Case report and literature review

Michalak

Milewski

Żurada

et al. 2015

Polish Annals of Medicine

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“…In these cases, it appears that differentiating gallbladder cancer from benign gallbladder diseases which also exhibit wall thickness with long-term and/or extreme inflammation is very difficult. There are also some case reports of false positive FDG-PET imaging in patients with adenomyomatosis without malignant tumors [18,19]. Maldijian et al [19] reported that the differential diagnosis of adenomyomatosis from gallbladder carcinoma was difficult due to a high SUVmax value (4.7) in the wall of the gallbladder.…”

Section: Discussionmentioning

confidence: 99%

“…There are also some case reports of false positive FDG-PET imaging in patients with adenomyomatosis without malignant tumors [18,19]. Maldijian et al [19] reported that the differential diagnosis of adenomyomatosis from gallbladder carcinoma was difficult due to a high SUVmax value (4.7) in the wall of the gallbladder. However, recently a study has been reported describing better results due to improved FDG-PET sensitivity, in which FDG-PET was performed in dual time-point (early and delayed period after 18 F-FDG injection) for differential diagnosis in patients with gallbladder disease [20].…”

Section: Discussionmentioning

confidence: 99%

Successful Diagnosis of Gallbladder Carcinoma Coexisting with Adenomyomatosis by 18F-FDG-PET—Report of a Case

Suzuki

Watada

Mitsui

et al. 2010

J Gastrointest Canc

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Adenomyomatosis of the Gallbladder: Another Cause for a “Hot” Gallbladder on ¹⁸F-FDG PET

Cited by 51 publications

References 7 publications

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Segmental type of gallbladder adenomyomatosis – Case report and literature review

Successful Diagnosis of Gallbladder Carcinoma Coexisting with Adenomyomatosis by 18F-FDG-PET—Report of a Case

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Adenomyomatosis of the Gallbladder: Another Cause for a “Hot” Gallbladder on 18F-FDG PET

Cited by 51 publications

References 7 publications

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Segmental type of gallbladder adenomyomatosis – Case report and literature review

Successful Diagnosis of Gallbladder Carcinoma Coexisting with Adenomyomatosis by 18F-FDG-PET—Report of a Case

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Adenomyomatosis of the Gallbladder: Another Cause for a “Hot” Gallbladder on ¹⁸F-FDG PET