Adenosquamous Carcinoma of the Penis Associated with Balanitis Xerotica Obliterans

Penile warty mucoepidermoid carcinoma with features of stratified mucin‐producing intra‐epithelial lesion and invasive stratified mucin‐producing carcinoma

“…In the 2016 World Health Organisation (WHO) classification of penile cancers, primary penile mucinous tumours with or without glands were considered adenosquamous, and the mucoepidermoid terminology was a synonym. Previously reported penile ASCs have shown glandular differentiation . ASC of other organs, such as those in the hypopharynx, larynx, trachea, gallbladder, extrahepatic bile ducts, pancreas, uterine cervix, vagina, vulva and prostate, manifest with glandular differentiation.…”

Advances in the pathology of penile carcinomas

“…About a dozen cases have been reported [16,[29][30][31][32][33][34]. The tumor originates in the glans central/perimeatal region and has a tendency for deep infiltration.…”

Adenosquamous Carcinoma of the Penis

“…Although radiotherapy has been used with success in selected cases of SCC, 1 it is probably not indicated for adenosquamous carcinoma due to the relative radioresistance of the glandular elements. 2 To date, chemotherapy has been initiated in only 1 case, 4 but the patient died within 2 weeks from septic complications.…”

“…Rarely, it may occur in the penis. [2][3][4][5] The squamous epithelium of penile skin is the site of origin of most primary penile tumors.…”

“…A review of the English language literature revealed that only 6 cases have been described since the first report of adenosquamous carcinoma of the penis by Jamieson et al in 1986. [2][3][4][5] …”