Adequacy of hemodialysis in Nepalese patients undergoing  maintenance hemodialysis

P, Sultania; Ps, Acharya; Sharma, Swati

doi:10.31729/jnma.179

Cited by 6 publications

(6 citation statements)

References 7 publications

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“…In this study majority of our patients were above 50 years of age which is similar to MHD population in this subcontinent. 8 The average age of MHD patients in Europe is 60, Japan 58 and in USA 60 years which is higher than current study. 9 This may be due to better socioeconomic condition, increased life expectancy and longer survival on dialysis.…”

Section: Discussioncontrasting

confidence: 65%

Quality of Life of Patients on Maintenance Hemodialysis in Relation to Hemoglobin Level: A Multicenter Study from a Developing Country

Saha

Masur²,

Choudhury

et al. 2017

Birdem Med J

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Background: Anemia is common in patients with end stage renal disease (ESRD) and is associated with impaired quality of life (QOL). This study was done to evaluate the QOL of ESRD patients on maintenance hemodialysis (MHD) with different levels of hemoglobin (Hb).Methods: This cross-sectional study was conducted from January to December 2013 on 135 adult ESRD patients on MHD for ?4 months, at hemodialysis units of three tertiary care hospitals in Dhaka, Bangladesh. The patients were divided into three groups based on Hb levels (Group 1: Hb <9 gm/dl, n=45, 33%; Group 2: Hb 9-11 gm/dl, n=53, 39% and Group 3: Hb >11 gm/dl, n=37, 28%), provided their Hb levels were stable [ie. maintained with erythropoietin (EPO) or blood transfusion (BT) or both] over the previous four months. Subjects were interviewed by principal investigator using Kidney Disease Quality of Life Short Form Tool (KDQOL-SF-36 version 1.3) consisting of two domains with 38 questions with each item put on a 0 to 100 range, higher scores indicating better QOL.Results: The mean age was 50+12 years with male predominance (male:female = 1.5:1). Mean duration of hemodialysis was 12±11.8 months (range 9 to 66 months). The average QOL score was 50. Comparison of QOL parameters between the three groups showed that symptoms/problems, effects of kidney disease, burden of kidney disease, cognitive function, quality of social interaction and sleep in the kidney disease specific domain as well as pain, emotional well-being, social function and energy/fatigue scale scores in the general health related domain were significantly higher in the group 2 and group 3 than group 1 patients (each with p<0.001). Comparison of QOL parameters between anemia correction measures like EPO (n=65, 48.2%), BT (n=42, 31.1%) or both (n=28, 20.7%) showed that the group receiving EPO alone had better QOL [symptom/ problem (p 0.043), burden of kidney disease (p 0.000), sexual function (p 0.000), pain (p 0.008) and energy/ fatigue (p 0.036)] compared to those getting BT or even BT plus EPO.Conclusion: Patients were found to have better QOL with higher Hb levels. The overall QOL can be improved significantly by correction of anemia.Birdem Med J 2017; 7(3): 198-204

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Section: Discussioncontrasting

confidence: 65%

Quality of Life of Patients on Maintenance Hemodialysis in Relation to Hemoglobin Level: A Multicenter Study from a Developing Country

Saha

Masur²,

Choudhury

et al. 2017

Birdem Med J

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“…HD is the most commonly used treatment option for this stage [2] a method that removes large amounts of uremic toxins with expected improvement of quality of life. However, hemodialysis, in itself, can lead to significant changes in patients' lifestyle and may possibly impair its quality [3]. This may be due to hemodialysis related complications as muscle cramps, pruritus, anorexia and access problems.…”

Section: Discussionmentioning

confidence: 99%

“…End stage renal disease (ESRD) is an increasing issue worldwide impairing patients Qol [1]. Hemodialysis (HD) is the mostly used for treatment [2] leading to overt changes in patients' lives [3,4].…”

Section: Introductionmentioning

confidence: 99%

Is health-related quality of life associated with adequacy of hemodialysis in chronic kidney disease patients?

et al. 2021

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Introduction Monitoring Health Related Quality of Life (HRQoL) in different stages of chronic kidney disease is advised by all nephrology societies. We aimed to study the relation between quality of life and dialysis adequacy. Methods One hundred patients (51% males), on regular hemodialysis 3/week for > 6 months in two hospitals were included. Single pool Kt/V was used to assess dialysis adequacy. Patients were grouped into 3 divisions according to Kt/v: Group A > 1.5 (n = 24), group B 1.2–1.5 (n = 54) and group C < 1.2 (n = 22). KDQOL-SF™ questionnaire was used to study quality of life in our groups. Group C was reassessed after 3 months of improving Kt/v. Results Mean values were: Kt/V (1.48 ± 0.41), Cognitive Function (84.27 ± 9.96), Work status (30.00 ± 33.33), Energy (45.70 ± 13.89), Physical Function and Role limitations due to physical function (45.30 ± 12.39 and 31.25 ± 19.26, respectively). Group A had significantly higher scores of KDQOL-SF except Role limitations due to Physical Function. All subscales improved in group C after Kt/v improvement except 3 subscales, namely, work status, patient satisfaction and role limitation due to physical and emotional functions. Conclusion Inadequate HD badly affects quality of life and improving adequacy refines many components of quality of life.

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“…In this study mean age of patients were Mean ± SD (53.37 ± 13.43) years (Table-1). Similarly Sultania et al of Nepal in their study showed that the mean age of the patients was 49±24 years 12 . One hundred (72.99%) patients were on 2 sessions (8 hours) per week hemodialysis group (Fig.…”

Section: Discussionmentioning

confidence: 70%

Assessment of Hemodialysis Adequacy in Patients with End Stage Renal Disease in a Military Hospital of Dhaka, Bangladesh

Rasul¹,

Rahman²,

Nessa³

et al. 2019

J. Bangladesh Coll. Phys.

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Introduction: The burden of kidney disease patients requiring renal replacement therapy is increasing day by day. Hemodialysis (HD) constitutes the most common form of renal replacement therapy (RRT) worldwide. Determining the adequacy of hemodialysis, Urea kinetic modeling (UKM) is an important tool for this. The aim of this study was to determine hemodialysis adequacy by UKM. Material & Methods: A total 137 patients were sampled in dialysis center of Combined Military Hospital (CMH) Dhaka. This was a cross sectional study. Data were collected from predialysis, postdialysis and next predialysis blood sample. Mean of adequacy parameters like single pool Kt/V (spKt/V), urea reduction ratio (URR), time average concentration of urea (TACurea) and normalized protein catabolic rate (NPCR) were calculated and compared between twice and thrice per week hemodialysis groups. Also compared adequacy variables between groups who achieved cutoff values and who did not achieve it. Results: One hundred (72.99%) patients were on 8 hours/week and 37 (27%) were on 12 hours/week hemodialysis session. Only 21(21%) and 16(43%) could achieve spKt/V cut off value among 8 hour and 12 hours group respectively. Eighty (58.39%) patients had URR < 65% in this study. Blood flow e+250 ml/ min group had significantly better dialysis adequacy than blood flow <250ml/min group, URR (81.31± 10.21 vs. 54.51 ± 11.52 and p-value <0.001), spKt/V (1.99 ± 0.41 vs. 1.41 ± 0.31 pvalue< 0.001) Thrice weekly hemodialysis group achieved better adequacy than twice weekly group. Conclusion: Frequency and blood flow of dialysis are strongly associated with adequacy of hemodialysis as evidenced by spKt/V and URR value. So to achieve hemodialysis adequacy, increasing the frequency of dialysis from two to three sessions per week is recommended. J Bangladesh Coll Phys Surg 2019; 37(4): 169-174

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Adequacy of hemodialysis in Nepalese patients undergoing maintenance hemodialysis

Cited by 6 publications

References 7 publications

Quality of Life of Patients on Maintenance Hemodialysis in Relation to Hemoglobin Level: A Multicenter Study from a Developing Country

Quality of Life of Patients on Maintenance Hemodialysis in Relation to Hemoglobin Level: A Multicenter Study from a Developing Country

Is health-related quality of life associated with adequacy of hemodialysis in chronic kidney disease patients?

Assessment of Hemodialysis Adequacy in Patients with End Stage Renal Disease in a Military Hospital of Dhaka, Bangladesh

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