Adequacy of Peritoneal Dialysis, Including Fluid Balance

Burkart, John M.; Bargman, Joanne M.

doi:10.1007/978-0-387-78940-8_16

Cited by 5 publications

(5 citation statements)

References 153 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dialysis adequacy (as total Kt/V per week) was determined for each patient based on blood urea concentration, 24-hour urine volume, urine urea concentration, 24-hour dialysate drain volume, dialysate urea concentration, weight, height, and age, using a Kt/V calculator (19). The peritoneal equilibration tests (PET) for glucose, creatinine and urea were performed for each patient based on a 2-L 4.25% dextrose dwell with dialysate samples at 0 and 4 hours and a blood sample during the dwell period.…”

Section: Methodsmentioning

confidence: 99%

Effects of Ginger on Serum Lipids and Lipoproteins in Peritoneal Dialysis Patients: A Randomized Controlled Trial

et al. 2016

View full text Add to dashboard Cite

♦ Background: In peritoneal dialysis (PD) patients, one of the major risk factors for cardiovascular disease is lipid abnormalities. This study was designed to investigate the effects of ginger supplementation on serum lipids and lipoproteins in PD patients. ♦ Methods: In this randomized, double-blind, placebo-controlled trial, 36 PD patients were randomly assigned to either the ginger or the placebo group. The patients in the ginger group received 1,000 mg ginger daily for 10 weeks, while the placebo group received corresponding placebos. At baseline and at the end of week 10, 7 mL of blood were obtained from each patient after a 12-to 14-hour fast, and serum concentrations of triglyceride, total cholesterol, low density lipoprotein-cholesterol (LDL-C), high density lipoproteincholesterol (HDL-C), and lipoprotein (a) [Lp (a)] were measured. ♦ Results: Serum triglyceride concentration decreased significantly up to 15% in the ginger group at the end of week 10 compared with baseline (p < 0.01), and the reduction was significant in comparison with the placebo group (p < 0.05). There were no significant differences between the 2 groups in mean changes of serum total cholesterol, LDL-C, HDL-C, and Lp (a). ♦ Conclusion: This study indicates that daily administration of 1,000 mg ginger reduces serum triglyceride concentration, which is a risk factor for cardiovascular disease, in PD patients.

show abstract

Section: Methodsmentioning

confidence: 99%

Effects of Ginger on Serum Lipids and Lipoproteins in Peritoneal Dialysis Patients: A Randomized Controlled Trial

et al. 2016

View full text Add to dashboard Cite

show abstract

“…The peritoneal membrane is more porous than the HD membrane, and PD has longer dialysis time (to 24 h of a day and 7 days a week) than intermittent HD. These two factors are associated with favorable removal of middle molecules ( 25 ). Various factors, associated with middle molecule removal such as the proportions of large size pore or vascularity within the peritoneal membrane, are associated with PPL among PD patients.…”

Section: Discussionmentioning

confidence: 99%

“…They introduced the middle molecule hypothesis, which explains the favorable removal of middle molecules during PD. Middle molecules, which weigh around 0.5-60 kD, are more effectively removed by convection combined with water removal than diffusion, which is dependent upon the difference in the molecule's concentration, and are removed in a time-dependent manner (24)(25)(26). The peritoneal membrane is more porous than the HD membrane, and PD has longer dialysis time (to 24 h of a day and 7 days a week) than intermittent HD.…”

Section: Discussionmentioning

confidence: 99%

Peritoneal Protein Loss Is Not Associated With Sarcopenia in Peritoneal Dialysis Patients

2021

View full text Add to dashboard Cite

Introduction: Maintenance of a peritoneal membrane is essential for maintaining long-term peritoneal dialysis (PD). Peritoneal protein loss (PPL) is basically the loss of an essential nutrient, which may lead to malnutrition. We aimed to evaluate the association between PPL and sarcopenia in PD patients.Methods: We conducted a cross-sectional study from September 2017 to November 2020 on all PD patients (n = 199). Finally, the patients were divided into tertiles based on the PPL level as follows: low, middle, and high. PPL (mg/day), appendicular lean mass (ALM) using dual-energy X-ray absorptiometry, and handgrip strength (HGS) were evaluated. Sarcopenia was defined using cut-off values from the Asian Working Group for Sarcopenia.Results: The median PPL (interquartile range, interval) in the low, middle, and high tertiles were 4,229 (904, 1,706–5,111), 6,160 (760, 5,118–7,119), and 8,543 (2,284, 7,145–24,406) mg/day, respectively. HGS in the low, middle, and high tertiles was 23.4 ± 9.2, 23.8 ± 8.9, and 23.6 ± 8.3 kg, respectively (P = 0.967). The ALM index in the low, middle, and high tertiles was 6.0 ± 1.3, 6.0 ± 1.2, and 6.5 ± 1.1 kg/m2, respectively (P = 0.061). Multivariate analyses did not reveal significant differences in HGS and ALM index in among tertiles. The proportions of patients with sarcopenia in the low, middle, and high tertiles was 24 (36.4%), 19 (28.4%), and 21 (31.8%), respectively (P = 0.612).Conclusion: The present study showed that PPL is not independently associated with muscle mass, strength, and sarcopenia in PD patients.

show abstract

“…Dialysis adequacy (as total Kt/V per week) was determined for each patient based on blood urea concentration, 24-hr urine volume, urine urea concentration, 24-hr dialysate drain volume, dialysate urea concentration, weight, height, and age, using a Kt/V calculator (Burkart & Bargman, 2009). The peritoneal equilibration test for glucose was performed for each patient based on a 2-L 4.25% dextrose dwell with dialysate samples at 0 and 4 hr and the calculation of the ratio of dialysate glucose concentration at time 4 to dialysate glucose level at time zero (D4/D0).…”

Section: Measurementsmentioning

confidence: 99%

Effects of soy isoflavones on serum systemic and vascular inflammation markers and oxidative stress in peritoneal dialysis patients: A randomized controlled trial

Yari

Tabibi²,

Najafi

et al. 2020

Phytotherapy Research

View full text Add to dashboard Cite

Cardiovascular disease (CVD) is common in peritoneal dialysis (PD) patients. This study was designed to investigate the effects of isoflavones on systemic and vascular inflammation markers and oxidative stress in PD patients. In this randomized clinical trial, 40 PD patients were randomly assigned to either the isoflavone or the placebo group. The isoflavone group received 100 mg soy isoflavones daily for 8 weeks, whereas the placebo group received corresponding placebos. At baseline and the end of eighth week, serum high sensitive C-reactive protein (hs-CRP), intercellular adhesion molecule type 1 (ICAM-1), vascular cell adhesion molecule type 1 (VCAM-1), E-selectin, and malondialdehyde were measured. Serum VCAM-1 decreased significantly in the isoflavone group at the end of Week 8 compared to baseline (p = .01), whereas no significant change was observed in the placebo group. Serum ICAM-1 decreased significantly in the isoflavone (p = .01) and placebo (p = .01) group compared to baseline. However, the reduction of ICAM-1 was significantly higher in the isoflavone group than in the placebo group (p = .02). There were no significant differences between the two groups in mean changes of serum E-selectin, malondialdehyde, and hs-CRP. This study indicates that isoflavones reduce serum VCAM-1 and ICAM-1, which are two CVD risk factors, in PD patients.

show abstract

Adequacy of Peritoneal Dialysis, Including Fluid Balance

Cited by 5 publications

References 153 publications

Effects of Ginger on Serum Lipids and Lipoproteins in Peritoneal Dialysis Patients: A Randomized Controlled Trial

Effects of Ginger on Serum Lipids and Lipoproteins in Peritoneal Dialysis Patients: A Randomized Controlled Trial

Peritoneal Protein Loss Is Not Associated With Sarcopenia in Peritoneal Dialysis Patients

Effects of soy isoflavones on serum systemic and vascular inflammation markers and oxidative stress in peritoneal dialysis patients: A randomized controlled trial

Contact Info

Product

Resources

About