Adherence to Mediterranean diet and 10‐year incidence (2002–2012) of diabetes: correlations with inflammatory and oxidative stress biomarkers in the ATTICA cohort study

Koloverou, Efi; Panagiotakos, D.; Pitsavos, Christos; Chrysοhoou, Christina; Georgousopoulou, Ekavi; Grekas, A.; Christou, A.; Chatzigeorgiou, Michael; Skoumas, Ioannis; Tousoulis, Dimitrios; Stefanadis, Christodoulos

doi:10.1002/dmrr.2672

Cited by 108 publications

(90 citation statements)

References 38 publications

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“…A recent analysis of the 10-year results of the ATTICA cohort study revealed that the risk of diabetes decreased by 49% and 62%, respectively, with medium and high adherence to the Mediterranean diet in the general nondiabetic population [6]. The present results show that the protective effect of the Mediterranean diet is even stronger in subjects with prediabetes, suggesting that this dietary pattern is protective over the entire spectrum of non-diabetic subjects including subjects with prediabetes.…”

Section: Level Of Adherence To the Mediterranean Dietsupporting

confidence: 57%

“…The antidiabetic effect of the Mediterranean diet in the non-diabetic population of the ATTICA cohort was mediated by attenuation of inflammation and enhancement of total antioxidant capacity [6].…”

Section: Level Of Adherence To the Mediterranean Dietmentioning

confidence: 92%

“…Recently, the 10-year results of the ATTICA cohort study revealed that medium and high adherence to the Mediterranean diet played a positive role in primary prevention of diabetes, mediated by attenuation of inflammation and increased total antioxidant capacity [6]. However, the effect of the Mediterranean diet on the prevention of diabetes and CVD has not been specifically studied in subjects with prediabetes.…”

Section: Introductionmentioning

confidence: 99%

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Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

et al. 2016

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■ AbstractBACKGROUND: Prediabetes has been related to an increased risk of developing diabetes and cardiovascular disease (CVD). AIM: The aim of the present study was to examine the effect of the Mediterranean diet on diabetes and CVD risk in subjects with impaired fasting glucose (IFG, i.e. fasting plasma glucose 100-125 mg/dl). METHODS: During 2001-2002, 3042 men and women (>18y) were enrolled for the study. The participants showed no clinical evidence of CVD or any other chronic disease, and were living in the greater Athens (Greece) area. In 2011 and 2012, the 10-year follow-up examinations were performed, including a working sample of n = 1875 participants without diabetes at baseline. Adherence to the Mediterranean diet at baseline evaluation was assessed using the MedDietScore (range 0-55). RE-SULTS: The prediabetic subjects (n = 343) had a significantly higher incidence of diabetes (25% vs. 10%, p < 0.001) and CVD (17.8% vs. 12.3%, p = 0.007) compared with subjects with normal glucose values. A significant trend towards lower diabetes and CVD incidence was observed with medium and high adherence to the Mediterranean diet compared with low adherence (p < 0.001). High adherence to the Mediterranean diet (>35/55 score) was associated with lower 10-year incidence of diabetes and CVD. In multiple logistic regression models, participants with high levels of adherence to the Mediterranean diet were significantly less affected by diabetes and CVD than those with low adherence levels. CONCLUSION: High adherence to the Mediterranean diet is associated with a low risk of developing diabetes and CVD in prediabetic subjects.

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Section: Level Of Adherence To the Mediterranean Dietsupporting

confidence: 57%

Section: Level Of Adherence To the Mediterranean Dietmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

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Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

et al. 2016

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“…400 BC), the concept of "food as medicine and medicine as food" has been followed and practiced among the different Western cultures. In the last few decades, several studies have shown that the Mediterranean diet can improve human health [1][2][3], particularly in relation to: a lower prevalence of cardiovascular disease [4][5][6][7][8][9], a possible effect on body weight and obesity regulation [10][11][12], a lower risk of type-2 diabetes mellitus [13][14][15], and to longevity improvement [2,16].…”

Section: Introductionmentioning

confidence: 99%

Gathering an edible wild plant: food or medicine? A case study on wild edibles and functional foods in Granada, Spain

2017

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A study on wild edible resources has been performed in the western part of Granada Province (Spain) using ethnobotanical methods. We document and analyze knowledge concerning wild edible plants and mushrooms and their folk medicinal uses in the study area. Several botanical features and use characteristics have been analyzed for the species included, with special attention to their medicinal uses, highlighting a large number of edible-medicinal species. Local importance of the medicinal uses for these resources has been confirmed. Up to 135 species are gathered from the wild in the study area, from which 46 can be considered folk functional foods. In addition, 45 crop plants with uncommon edible or medicinal uses are included, 29 of these being considered functional foods as well. Therefore, a total of 75 plant species are used as edible medicines which serve to treat 36 different conditions. The local concept of food and medicine regarding wild plant resources seems not to be well established. Studies on the pharmacological properties of these foods are needed in order to establish their real or potential benefits for the treated affections.

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“…Diet is considered a milestone in diabetes primary prevention, with various dietary patterns being effective in preventing diabetes development [2][3][4]. Medical nutrition therapy (MNT) after diabetes diagnosis is of major importance.…”

Section: The Role Of Medical Nutrition Therapy In Diabetes Managementmentioning

confidence: 99%

Macronutrient Composition and Management of Non-Insulin-Dependent Diabetes Mellitus (NIDDM): A New Paradigm for Individualized Nutritional Therapy in Diabetes Patients

Koloverou

Panagiotakos

2016

Rev Diabet Stud

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■ AbstractMedical nutrition therapy constitutes an important lifestyle intervention in diabetes management. Several nutrition patterns have been effective in improving diabetes control, but there has been a debate about the optimal macronutrient composition in diabetes meal planning. For many years, the recommended diets for persons with and without diabetes were similar, i.e. heart-healthy and low in fat. For almost three decades, carbohydrates have been lauded, lipids demonized, and proteins considered of little importance. However, in the past few years, this concept has been questioned and reassessed. Modern nutritional recommendations for people with diabetes are headed towards individualization, but lack specific guidelines. Nutritional algorithms may help nutritionists in diabetes meal planning. This review aims to discuss: 1) the effects of the three major macronutrients (carbohydrates, proteins, and lipids) on glucose levels, 2) current recommendations for macronutrient intake for people with diabetes, and 3) specific parameters that need to be taken into consideration when determining the macronutrient composition for a person with diabetes, for example body mass index, degree of insulin resistance, HbA1c value, and lipid profile (especially triglycerides and HDL cholesterol). These aspects are analyzed in the context of the results of recent studies, especially randomized controlled trials (RCTs). Finally, we introduce an individualized nutritional concept that proposes carbohydrate over lipid restriction, substitution of SFAs with MUFAs and PUFAs, and adequate intake of dietary fiber, which are key factors in optimizing diabetes management.

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Adherence to Mediterranean diet and 10‐year incidence (2002–2012) of diabetes: correlations with inflammatory and oxidative stress biomarkers in the ATTICA cohort study

Cited by 108 publications

References 38 publications

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study

Gathering an edible wild plant: food or medicine? A case study on wild edibles and functional foods in Granada, Spain

Macronutrient Composition and Management of Non-Insulin-Dependent Diabetes Mellitus (NIDDM): A New Paradigm for Individualized Nutritional Therapy in Diabetes Patients

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