Adherence to the Mediterranean Diet in Relation to Ischemic Stroke Nonfatal Events in Nonhypercholesterolemic and Hypercholesterolemic Participants

Kastorini, Christina-Maria; Milionis, Haralampos; Kantas, D.; Bika, Eftychia; Nikolaou, Vassilios S.; Vemmos, Konstantinos; Goudevenos, John; Panagiotakos, Demosthenes B.

doi:10.1177/0003319711427392

Cited by 14 publications

(10 citation statements)

References 33 publications

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“…Some epidemiological studies have also examined the association between a MDS and the risk of stroke. Among these, some (31,38,39) found an inverse association, while others did not (17,40) . Moreover, a recent paper has found an inverse association between adherence to a Mediterranean-like diet and total cerebrovascular disease (41) .…”

Section: Discussionmentioning

confidence: 97%

The Mediterranean diet in relation to mortality and CVD: a Danish cohort study

et al. 2013

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The aim of the present study was to determine whether the Mediterranean Diet Score (MDS) is associated with reduced total mortality, cardiovascular incidence and mortality in a Danish population. Analyses were performed on 1849 men and women sampled during the 1982 -83 Danish MONICA (MONItoring trends and determinants of Cardiovascular disease) population study, whose diet was assessed by means of a validated 7 d food record. The adherence to a Mediterranean dietary pattern was calculated by three different scores: one based on a classification excluding ingredients from mixed dishes and recipes (score 1); another based on a classification including ingredients (score 2); the last one based on a variant of the latter including wine instead of alcohol intake (score 3). The association between these scores and, respectively, total mortality, cardiovascular incidence and mortality was tested by a Cox proportional hazards model adjusted for several potential confounders of the association. Generally, all three scores were inversely associated with the endpoints, although associations with score 1 did not reach statistical significance. Score 2 was inversely associated with total mortality (hazard ratio 0·94; 95 % CI 0·88, 0·99). This association was confirmed for total cardiovascular as well as myocardial infarction (MI) incidence and mortality, but not for stroke. Score 3 was slightly more associated with the same outcomes. All associations were also resistant to adjustment for covariates related to potential CVD pathways, such as blood lipids, blood pressure and weight change after 11 years of follow-up. In a Danish cohort, the MDS was inversely associated with total mortality and with cardiovascular and MI incidence and mortality, but not with stroke incidence or mortality.

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Section: Discussionmentioning

confidence: 97%

The Mediterranean diet in relation to mortality and CVD: a Danish cohort study

et al. 2013

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“…In addition, the EPIC (European Investigation into Cancer and Nutrition) provided important evidence, based on analyses on large numbers of subjects [57]. Along these new approaches, several other concepts have emerged such as the protective role of the Mediterranean diet on renal function [58] and on the levels of serum uric acid [59], on weight control [60], on metabolic syndrome [61] and on developing ischaemic stroke [62]. Moreover, the study of the Mediterranean diet stimulated important comparative procedures between the a priori and the a posteriori approach for the definition of dietary patterns [63].…”

Section: Discussionmentioning

confidence: 99%

How the Seven Countries Study contributed to the definition and development of the Mediterranean diet concept: A 50-year journey

Menotti

Puddu

2015

Nutrition, Metabolism and Cardiovascular Diseases

111

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“…In relation to CVD, there are several studies analyzing the effects of a priori 264 defined MDP, that found a cardio-protective effect of this DP [23,24]. However, different 265 28 country-specific DP have been described in Mediterranean populations and these results 266 should be interpreted with caution.…”

Section: Discussion 224mentioning

confidence: 99%