Adjunctive use of essential oils following scaling and root planing –a randomized clinical trial

Abstract

BackgroundHitherto no study has been published on the effect of the adjunctive administration of essential oils following scaling and root planing (SRP). This study describes the effect of a mouthrinse consisting of essential oils (Cymbopogon flexuosus, Thymus zygis and Rosmarinus officinalis) following SRP by clinical and microbiological variables in patients with generalized moderate chronic periodontitis.MethodsForty-six patients (aged 40–65 years) with moderate chronic periodontitis were randomized in a double-blind study and rinsed their oral cavity following SRP with an essential oil mouthrinse (n = 23) or placebo (n = 23) for 14 days. Probing depth (PD), attachment level (AL), bleeding on probing (BOP) and modified sulcus bleeding index (SBI) were recorded at baseline and after 3 and 6 months. Subgingival plaque was taken for assessment of major bacteria associated with periodontitis.ResultsAL, PD, BOP and SBI were significantly improved in both groups after three (p < 0.001) and 6 months (p ≤ 0.015). AL improved significantly better in the test than in the control group after 3 and 6 months (p < 0.001), so did PD after three months in the tendency (p = 0.1). BOP improved better in the test group after 3 months (p = 0.065). Numbers of Treponema denticola (p = 0.044) and Fusobacterium nucleatum (p = 0.029) decreased more in the test than in the control group after 3 months, those of Tannerella forsythia after 6 months (p = 0.039). Prevotella micra (p < 0.001, p = 0.035) and Campylobacter rectus (p = 0.002 , p = 0.012) decreased significantly in both groups after 3 months.ConclusionsThe adjunctive use of a mouthrinse containing essential oils following SRP has a positive effect on clinical variables and on bacterial levels in the subgingival biofilm.Trial registration332-12-24092012, DRKS 00009387, German Clinical Trials Register, Freiburg i. Br., 16.09.2015Electronic supplementary materialThe online version of this article (doi:10.1186/s12906-016-1117-x) contains supplementary material, which is available to authorized users.

Efficacy of an All-Natural Polyherbal Mouthwash in Patients With Periodontitis: A Single-Blind Randomized Controlled Trial

“…A recent study investigated whether the adjunctive use of a mouthwash containing three natural essential oils ( Cymbopogon flexuosus oil, Thymus Zygis oil, Rosmarinus officinalis ) following sub-gingival debridement and scaling and root planning (SRP) could improve the clinical results regarding changes of the clinical parameters of PD, CAL and bleeding on probing (BoP) (Azad et al, 2016). Significant improvements of AL, PD, and BoP occurred in both groups after 3 months ( p < 0.001); PD and BoP being significantly lower in the TG.…”

Developing natural products as potential anti-biofilm agents

“…Mouthwash containing essential oil might also be more effective in killing dental bacteria. A randomized-controlled clinical trials involving patients with moderate chronic periodontitis indicated that combined using mouthwash with essential oil from Cymbopogon flexuosus , Thymus zygis and Rosmarinus officinalis had anti-biofilm potential in the subgingiva in patients with good tolerability [ 94 ]. As indicated in a randomized double-blind trail, mouthrinses consist of Lemongrass oil reduced oral malodour for 8-day treatment, which might due to its selectively anti-microbial effect against Aggregatibacter actinomycetemcomitans ATCC43718 and Porphyromonas gingivalis W50 [ 95 ].…”

Clinical Assessment of Rosemary-based Toothpaste (Rosmarinus officinalis Linn.): A Randomized Controlled Double-blind Study

“…(rosemary), which is widely used in food, cosmetics, spices and flavoring in many countries. A number of authors have conducted clinical trials to assess the effectiveness of toothpastes containing herbs, as well as, there are reports in the scientific literature of researches with mouthwashes which contained the rosemary in its composition (5,(18)(19)(20). However, the present study is the first to perform clinical analysis on rosemary using oral health indices and a defined therapeutic dose of the plant extract.…”

“…Natural products are a valuable and unexplored source of potentially effective antimicrobials, with low levels of toxicity. Recent advances in analytical technology, particularly those related to phytotherapy, have created a new era of anti-plaque therapies and natural products (17,18). In this sense, plant extracts and their compounds appear as na alternative for the treatment of periodontal diseases in view of the fact that pharmacological research evoked the antibacterial and anti-inflammatory activities of rosemary.…”