Adjuvant Radiotherapy in Breast Cancer: The Treatment of Lymph Node Areas

Arriagada, R.; Lê, Monique G.

doi:10.1080/028418600750013041

Cited by 25 publications

(14 citation statements)

References 93 publications

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“…The rationale of supraclavicular irradiation is that the addition of such adjuvant treatment would improve the survival of patients (19)(20)(21). In our series the main site of relapse and death predictor for patients with PAN was not SFR but DM.…”

Section: Discussionmentioning

confidence: 81%

Outcome After Conservative Surgery and Breast Irradiation in 5,717 Patients With Breast Cancer: Implications for Supraclavicular Nodal Irradiation

Livi¹,

Scotti²,

Saieva³

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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Section: Discussionmentioning

confidence: 81%

Outcome After Conservative Surgery and Breast Irradiation in 5,717 Patients With Breast Cancer: Implications for Supraclavicular Nodal Irradiation

Livi¹,

Scotti²,

Saieva³

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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“…The reappraisal of internal mammary node metastases as a prognostic factor and the results of recent publications of trials of postmastectomy irradiation have aroused discussion about adopting routine elective IMN irradiation despite potential serious cardiac morbidity (4)(5)(6).…”

mentioning

confidence: 99%

Patient Preference for Dissection of Sentinel Nodes Outside Level I-II of the Axilla

2002

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In this study patients' and female doctors' opinions about harvesting sentinel nodes outside the axilla are evaluated and patients' ability to understand the concept of sentinel node biopsy is investigated. Information leaflets and questionnaires were mailed to 100 patients with breast cancer who had undergone sentinel node biopsy and to 300 female doctors. Seventy-three (73%) patients and 148 (49%) female doctors returned the questionnaire. Fifty-eight (79%) breast cancer patients and 71 (48%) female doctors wanted harvesting to be done in order to determine whether the nodes were involved. Sixty-six (90%) patients and 128 (86%) female doctors wanted the procedure if it changed the treatment. Sixty (82%) patients understood the outcome of the sentinel node procedure. Patients with breast cancer seem to value the information gained by harvesting sentinel nodes outside the axilla and want the procedure if there is even the slightest possibility that it might change the adjuvant treatment.

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“…This result concedes with that of Arriagada et al, Voogd et al, Le and Vinh -Hung et al who also found that the recurrence rate raises as the number of positively involved axillary lymph nodes increases. [22][23][24][25] Considering the correlation between extracapsular extension of the positively involved axillary lymph nodes and risk of recurrence, patients with the presence of extracapsular extension carried about twice the risk of recurrence of those without extracapsular extension (20% in the former versus 9% in the latter). Similar results were found by Tulay et al who also found that extracapsular extension had significant prognostic value in predicting the recurrence in Ca breast.…”

Section: Discussionmentioning

confidence: 99%

The predictors and the prognostic significance of axillary lymph nodes involvement in breast cancer

et al. 2019

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Background: Breast cancer is the most common cancer among women worldwide. The presence of axillary lymph node metastases in breast cancer is an important factor in assessing prognosis and determines management after surgery. The study aimed at identification of the factors that predict axillary lymph node involvement in CA breast. Addressing the prognostic effect of axillary lymph node involvement in turn of predicting the recurrence of CA breast.Methods: This is a prospective review of one hundred cases of Ca breast who have underwent modified radical mastectomy and axillary clearance at Al-Karama Teaching Hospital during the period from January 2014 to December 2018.Results: Positive axillary involvement was found in (74/100, 74%). The highest occurrence of positive axilla was found in (less than 30 and 30-39 years) age groups (27/74, 36%) with the outer quadrants (upper and lower) constituting the majority (50/74, 68%). Positive axillary involvement was mostly notified in tumor grade T4 (39/74, 53%) and in poorly differentiated lesions (47/74, 64%). The highest recurrence rate was found in patients with positive axillary metastases (12/74, 16%), nodal involvement of ten or more nodes (9/41, 22%), nodes with extracapsular extension (10/51, 20%) and in patients who have not taken and/or completed their chemo-radiation sessions (9/11, 82%).Conclusions: Positive axillary lymph node involvement was seen mostly in: young age patients, outer quadrant lesions, tumors with skin involvement, and poorly differentiated lesions.

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Adjuvant Radiotherapy in Breast Cancer: The Treatment of Lymph Node Areas

Cited by 25 publications

References 93 publications

Outcome After Conservative Surgery and Breast Irradiation in 5,717 Patients With Breast Cancer: Implications for Supraclavicular Nodal Irradiation

Outcome After Conservative Surgery and Breast Irradiation in 5,717 Patients With Breast Cancer: Implications for Supraclavicular Nodal Irradiation

Patient Preference for Dissection of Sentinel Nodes Outside Level I-II of the Axilla

The predictors and the prognostic significance of axillary lymph nodes involvement in breast cancer

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