Administration of mushroom extract to broiler chickens for bifidobacteria enhancement and Salmonella reduction

Willis, W. L.; King, Kerryn; Iskhuemhen, O. S.; Ibrahim, Salam A.

doi:10.3382/japr.2008-00101

Cited by 25 publications

(20 citation statements)

References 18 publications

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“…Previous studies have reported the addition of probiotics promoted the intestinal health by improving the intestinal bacterial community and the tight junction of the intestines ( Bäumler and Sperandio, 2016 ). Increasing the abundance of Lactobacillus and Bifidobacteria in the gut can inhibit Salmonella infection ( Willis et al., 2009 ; Olnood et al., 2015 ). The energy level of the diet is associated with the Lactobacillus abundance in the gut ( Chen et al., 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Highly nutritious diet resists Salmonella Typhimurium infections by improving intestinal microbiota and morphology in broiler chickens

Yang

Dong

et al. 2020

Poultry Science

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Salmonella Typhimurium ( S. Typhimurium) infection in broiler chickens threatens public health and livestock production. In this study, we explored the effects of highly nutritious (crude protein 21.8%, metabolizable energy 3.16 Mcal/kg) and lowly nutritious (crude protein 18.1%, metabolizable energy 2.98 Mcal/kg) diets on S. Typhimurium infection by altering the intestinal morphology and environment in broiler chickens. The highly nutritious diet significantly increased the body weight gain and reduced feed conversion ratio on day 1 to 21 ( P < 0.01). The highly nutritious diets promoted the intestinal villus height, crypt depth, and their ratio to improve the intestinal epithelial maturation ( P < 0.05). Highly nutritious diets significantly increased the expression of claudin-1, occludin, and NF-κB genes in the intestinal epithelium on the days of 14 and 21 ( P < 0.05). S. Typhimurium activated the expression of TLR4 , MyD88 , and NF-κB genes to cause an inflammatory response. The S. Typhimurium can increase the activity of myeloperoxidase, which cause an inflammatory response. The S. Typhimurium significantly reduced the diversity indexes of the ileal microbiota ( P < 0.05), increased the abundance of Cyanobacteria which can synthesize toxins. The highly nutritious diet group challenged with S. Typhimurium can increase the abundance of Lactobacillus in the ileum, which lead to improved intestinal health ( P < 0.05). It is concluded that increasing the nutritional level of dietary is beneficial to improve the resistance to S. Typhimurium infection by altering the intestinal bacterial community.

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Section: Introductionmentioning

confidence: 99%

Highly nutritious diet resists Salmonella Typhimurium infections by improving intestinal microbiota and morphology in broiler chickens

Yang

Dong

et al. 2020

Poultry Science

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“…The Salmonella infection in broiler chickens mainly causes intestinal health problems that seriously reduce growth performance and increases the spread of drug-resistant genes [5]. The increase of beneficial microorganisms in the intestines, such as Lactobacillus and Bifidobacteria, can against the Salmonella infections [6]. Therefore, changing the composition of gut microbes can be used as a strategy to resist the challenge of Salmonella and improve the growth performance of animals [7].…”

Section: Introductionmentioning

confidence: 99%

“…Studies have shown that Salmonella infection in broiler chicken caused intestinal immune responses and improved the inflammation-related gene expressions of IFNγ , IL-12 , and IL-18 [14]. The resistance to Salmonella can be improved by regulating the intestinal bacteria [6]. A large number of previous studies have focused on the therapeutic effect of antibiotics against S. typhimurium infection [15,16].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

Yang

Dong

et al. 2019

Microorganisms

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The composition of the bacterial community affects the intestinal health and growth performance of broiler chickens. The main purpose of this study was to explore the effects of flavomycin and colistin sulfate on the resistance to Salmonella typhimurium infection, ileal bacteria and intestinal health. In total, 396 1-day-old broiler chickens were randomly divided into six groups. Two groups were fed each one of the diets—the control diet (CON), the flavomycin at 10 mg/kg diet (AntiG+), and the colistin sulfate at 40 mg/kg diet (AntiG−), for 5 days. Then, one of each of the two groups was challenged with S. typhimurium on the 8th day; these were named CONS, AntiG+S and AntiG−S, respectively. The results showed that S. typhimurium significantly reduced the feed intake and body weight gain, and increased the feed conversion ratio (p < 0.05). It also increased the inflammatory expressions of NF-κB and MyD88 genes (p < 0.05); and reduced the expressions of claudin-1, occludin and mucin-2 (p < 0.05) tight junction genes in the intestines. S. typhimurium significantly reduced ileal bacterial diversity indexes of observed-species, chao1 and Shannon (p < 0.05). Compared with AntiG+S group, AntiG−S group increased the body weight gain of broiler chickens (p < 0.05), reduced the expression of inflammatory genes (p < 0.05) and intestinal permeability to fluorescein isothiocyanate (p < 0.05). AntiG-S group also improved the ileal bacterial diversity indexes of observed-species and Shannon (p < 0.05). There were many significant correlations between intestinal bacteria, intestinal gene expressions and intestinal morphology (p < 0.05). This study indicated that pre-constructed AntiG− bacteria could against a S. typhimurium infection by inhibiting the expressions of intestinal inflammation genes and increasing the diversity of intestinal bacteria.

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“…Lactobacillus). On the other hand, Willis et al (2009) found that herb polysaccharides had effects similar to those of prebiotic.…”

Section: Statisticsmentioning

confidence: 88%

The effects of different levels of Aloe vera gel on ileum microflora population and immune response in broilers: a comparison to antibiotic effects

Darabighane

Zarei

Shahneh

2012

Journal of Applied Animal Research

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The purpose of the present research is to study the effects of different levels of Aloe vera gel on microflora population, humoral and cellular immune response, and relative weight of lymphoid organs compared to the effects brought about by antibiotic. The groups included the control group (basal diet) as well as three groups with different levels of Aloe vera gel (added to basal diet at 1.5%, 2% and 2.5%), and finally a group with basal diet supplemented by 15 ppm virginiamycin antibiotic. Regarding ileum microflora, the increase in Aloe vera gel in the feed resulted in significant reduction in the number of E. coli colonies and significant increase in the number of Lactobacillus colonies compared to the control and antibiotic groups. As far as humoral immunity is concerned, Newcastle disease virus antibody titre on the 24th and 38th day was the highest in 2.5% and 2% Aloe vera gel groups, respectively. In addition, sheep red blood cells antibody titre reached its highest level in the 2.5% Aloe vera gel group on the days 24, 28, 34 and 38. The differences among the groups regarding sheep red blood cells antibody titre were significant on the days 24, 28 and 34, while no significant differences were observed on the 38th day. Regarding the cellular immunity, the highest response was obtained by injecting phytohemagglutinin-P and the highest relative weight of spleen and bursa of Fabricius was found in the 2.5% Aloe vera gel group. The findings of the study suggest reduction in number of E. coli colonies and increase in number of Lactobacillus colonies as a result of increased Aloe vera gel in the feed. Furthermore, the 2.5% Aloe vera gel group resulted in significantly higher levels of humoral and cellular immunity, as well as relatively greater weight of lymphoid organs, which suggests that Aloe vera gel can be a proper replacement for the virginiamycin antibiotic.

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Administration of mushroom extract to broiler chickens for bifidobacteria enhancement and Salmonella reduction

Cited by 25 publications

References 18 publications

Highly nutritious diet resists Salmonella Typhimurium infections by improving intestinal microbiota and morphology in broiler chickens

Highly nutritious diet resists Salmonella Typhimurium infections by improving intestinal microbiota and morphology in broiler chickens

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

The effects of different levels of Aloe vera gel on ileum microflora population and immune response in broilers: a comparison to antibiotic effects

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